1Define poison:
A substance that is harmful when ingested.
2Define toxin:
An harmful poison or venom or plant or animal origin.
3Define toxicant:
A harmful poison or venom of either organic or inorganic origin.
4Define xenobiotic:
Substance that is foreign to the body
5Define endobiotic:
Substance that is not foreign to the body and can be found
6What are the requirements to produce a toxic effect?
Substance must get to the target site, high enough concentration, long enough amount of time exposed.
7What do LD, TD, LC and TC all mean
Lethal dose, Toxic dose, Lethal concentration, Toxic concentration.
8What does LD50 mean?
50% of animals died when exposed to that amount of dosage.
9Give example of exposure sites...
GI tract, lungs, skin
10What are the 3 main routes of exposure?
Inhalation, Ingestion and Dermal.
11What are the 2 kinds of exposure, explain them...
Acute and Chronic, Short term or one time exposure vs long term exposure.
12Explain Threshold concept...
The maximum exposure when toxic effects will not occur to the exposed individual.