Endocrine Glands

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1
What are the differences between endocrine and exocrine glands?
Endocrine glands secrete hormones via the bloodstream to their target organs whereas exocrine glands secrete directly to their target organs; Endocrine secretions is a delayed response wheres exocrine secretions are a rapid response
2
What are some examples of endocrine glands?
Pancreas, thyroid, parathyroid, adrenal gland and pituitary gland
3
What are some example of exocrine glands?
Mammary glands, sebaceous glands, sweat glands
4
What is the cavernous sinus?
Large venous sinus located on either side of the sella turcica
5
What is the bony structure that houses the pituitary gland at the base of the skull?
Sella turcica
6
The sella turcica is a part of which bone of the skull?
Sphenoid
7
What are the functions of the cavernous sinsu?
Thermoregulation - due to close proximity of the internal carotid artery; Venous blood drainage of the brain, eye and face; Neurovascular conduit - houses some cranial nerves; Pathway for infection spread via danger triangle
8
What is cavernous sinus fistula?
An abnormal connection between the internal carotid artery and the cavernous sinus which can lead to increased pressure within the sinus whoch presents with symptoms such as vomitting and nausea
9
What cranial nerves are located in the cavernous sinus?
III,IV,VI and V2 and V3
10
Which cranial nerve is located next to the internal carotid artery in the cavernous sinus rather than the lateral wall?
Abducens - CN VI
11
Where is the hypothalamus located?
Below the thalamus and above the pituitary gland
12
What structure is known as the pituitary stalk and connects the hypothalamus to the pituitary gland?
Infundibulum
13
What is the function of the hypothalamus?
Has portal vessels which regulate the anterior lobe and hypothalamic axons which connect directly to the posterior lobe
14
What is the function of the pituitary gland?
Control secretions of many hormones involved in metabolism, reproduction, stress responses and growth
15
What is secreted from the posterior lobe of the hypothalamus?
ADH; Oxytocin
16
What is the blood supply of the pituitary gland?
Hypophyseal arteries
17
What is the nerve supply to the pituitary gland?
Hypothalamo hypophyseal tract
18
What is secreted from the anterior lobe of the pituitary gland?
FSH; LH; TSH; Prolactin; GH; ATCH
19
Describe the anterior pituitary gland ad hypothalamus relation ship.
Connected via the hypophyseal portal system - blood vessel connect them
20
Describe the posterior pituitary gland and hypothalamus reltionship.
Connected by the neurophysis - nerve fibres connect them
21
What is the hypophyseal portal system?
Pathway through which hormones from the hypothalamus reach the anterior pituitary
22
What is Cushing’s syndrome?
When too much cortisol is secreted
23
How does Cushing’s syndrome present?
Round moon face; Hump back; Stretch marks; Thin hair; Thin brusises
24
What is Cushing’s Disease?
A subset of Cushing’s syndrome caused by too much ATCH secretion
25
A pituitary ademona where could lead to bitemporal hemianipoia?
In the optic chiasm
26
What does the adrena cortex secrete?
Aldosterone; Cortisol; Androgens
27
What does the adrenal medulla secrete?
Noradrenaline; Adrenaline
28
What nucleus in the hypothalamus is responsible for ADH secretion?
Supraoptic nucleus
29
What nucleus in the hypothalamus is responsible for Oxytocin secretion?
Paraventricular nucleus
30
Where are the adrenal glands located?
Superior poles of the kidneys
31
What is the shape of the left and right adrenal glands?
The right adrenal gland has a pyrimidal shape; The left adrenal gland has a crescent shape
32
What is the function of the adrenal glands?
Secrete hormones in response to stress and metabolism
33
What are the two central regions of the adrenal glands?
Adrenal medulla and adrenal cortex
34
What are the three zones of the adrenal cortex?
Zone of fasciculata; Zone of glomerulosa; Zone of reticularis
35
What is the function of adrenal capsule?
Anchors the adrenal gland to the surrounding tissues; Acts as a barrier between the gland and the surrounding fat and fascia
36
What is the hilum of the adrenal glands?
Points of exit of the veins and lympathics which are located within the capsule
37
What cells in the adrenal medulla secrete catecholamines?
Chromaffin cells
38
What hormones is secreted from the zona glomerulosa?
Aldosterone and other mineralocorticoids
39
What hormone is scereted from the zona fasciculata?
Cortisol and other glucocorticoids
40
What hormone is secreted frome the zona reticularis?
Androgens
41
Describe the nerve supply to the adrenal glands?
Mainly from the coeliac plexus and the thoracic splanchnic nerves
42
What arteries supply the adrenal glands?
Superior suprarenal arteries from the inferior phrenic artery; Middle suprarenal artery from the SMA; Inferior suprarenal artery from the renal artery
43
Where does lymphatics from the kidney drain into?
Lumbar lymph nodes
44
Where does the left and right suprarenal vein drain into?
Right drains into the IVC; Left drains into the left renal vein
45
What are the infrahyoid muscles and what are their functions?
Sternohyoid, omohyoid, thyrohyoid and sternothyroid; Depress hyoid
46
What is the pretracheal fascia?
Connects the STRAP muscles and the thyroid together
47
What is the function of the thyroid gland?
It produces hormones T4,T3 and calcitonin that regulate metabolism, growth and calcium balance
48
What is the shape of the thyroid gland?
Butterfly shape
49
What is the nerve supply to the thyroid?
C5 to T1
50
Describe the special features of the thyroid.
Has a pyrimidal lobe which may extend upwards from the isthmus; Has a capsule which surrounds the gland; Isthmus is a band of tissue connecting the two lobes together
51
What is the nerve supply of the thyroid?
Cervical ganglia and vagus nerve
52
What hormones does the thyroid produce?
T3,T4 and calcitonin
53
What is the ligament of berry?
Ligament which connects the throid to the trachea
54
What is the significance of the ligament of berry and tubercle of zuckerandi
Surgical landmark for protecting the recurrent laryngeal nerve
55
What is the tubercle of zuckerandi?
Posterior projection of the lateral lobes of the thyroid galnd
56
Describe the blood supply to the thyroid.
Superior thyroid artery - branch of the external carotid; Thyroid ima artery - branch of the brachiocephalic trunk; Inferior thyroid artery - branch of the thyrocervical trunk
57
Wheres does the superior and middle thyroid veins drain into?
Inferior vena cava
58
Where does the inferior thyroid vein drain into?
Branchiocephalic vein
59
What is a thyroglossal cycst?
An abnormal cysts that forms in the foramen caecum that moves with the tongue
60
What is goitre?
Enalrgement of the thyroid which moves with swallowing
61
What is the function of the parathyroid gland?
Produces parathryoid hormone needed in regulation of calcium
62
How many parathyroid glands are there?
FOUR
63
Where are the parathyroid glands found in relation to the thyroid?
Found on the posterior side of the thyroid
64
Describe the primary arterial supply to the parathyroid glands.
Inferior thyroid artery
65
Describe the collateral supply to the parathyroid glands.
Superior thyroid artery; Very rarely the thyroid ima artery
66
Describe the nerve supply to the parathyroid glands.
Vagus nerve for parasymtpathetic; Cervical ganglia
67
What is the function of the pancreas?
Endocrine and exocrine organ which secretes hormones and enzymes
68
What vertebral level is the pancreas located at?
L1/L2
69
What are the four parts of the pancreas?
Head; Neck; Body; Tail
70
What is the uncinate process of the pancreas?
A hook-shaped projection of the pancreatic head that extends posterior to the superior mesenteric vessels
71
What is the function of the sphincter of oddi?
Prevents backflow of substances back into the pancreatic or common bile duct
72
What is the ampulla of vater?
Connection of thertr the main pancreatic duct and the common bile duct meet
73
Describe the blood supply to the pancreas.
Body and Tail is supplied by the splenic artery; Head is supplied by a branch of the gastroduodenal artery
74
What vein drains the pancreas?
Splenic veins and superior meseneteric veins
75
Describe the nerve supply to the pancreas?
76
What does epigastric pain radiating to the back suggest?
Pancreatic issues
77
What does steatorrhea suggets?
78
What does jaundice suggest?
Blockage in biliary system
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