1What are the differences between endocrine and exocrine glands?
Endocrine glands secrete hormones via the bloodstream to their target organs whereas exocrine glands secrete directly to their target organs; Endocrine secretions is a delayed response wheres exocrine secretions are a rapid response
2What are some examples of endocrine glands?
Pancreas, thyroid, parathyroid, adrenal gland and pituitary gland
3What are some example of exocrine glands?
Mammary glands, sebaceous glands, sweat glands
4What is the cavernous sinus?
Large venous sinus located on either side of the sella turcica
5What is the bony structure that houses the pituitary gland at the base of the skull?
Sella turcica
6The sella turcica is a part of which bone of the skull?
Sphenoid
7What are the functions of the cavernous sinsu?
Thermoregulation - due to close proximity of the internal carotid artery; Venous blood drainage of the brain, eye and face; Neurovascular conduit - houses some cranial nerves; Pathway for infection spread via danger triangle
8What is cavernous sinus fistula?
An abnormal connection between the internal carotid artery and the cavernous sinus which can lead to increased pressure within the sinus whoch presents with symptoms such as vomitting and nausea
9What cranial nerves are located in the cavernous sinus?
III,IV,VI and V2 and V3
10Which cranial nerve is located next to the internal carotid artery in the cavernous sinus rather than the lateral wall?
Abducens - CN VI
11Where is the hypothalamus located?
Below the thalamus and above the pituitary gland
12What structure is known as the pituitary stalk and connects the hypothalamus to the pituitary gland?
Infundibulum
13What is the function of the hypothalamus?
Has portal vessels which regulate the anterior lobe and hypothalamic axons which connect directly to the posterior lobe
14What is the function of the pituitary gland?
Control secretions of many hormones involved in metabolism, reproduction, stress responses and growth
15What is secreted from the posterior lobe of the hypothalamus?
ADH; Oxytocin
16What is the blood supply of the pituitary gland?
Hypophyseal arteries
17What is the nerve supply to the pituitary gland?
Hypothalamo hypophyseal tract
18What is secreted from the anterior lobe of the pituitary gland?
FSH; LH; TSH; Prolactin; GH; ATCH
19Describe the anterior pituitary gland ad hypothalamus relation ship.
Connected via the hypophyseal portal system - blood vessel connect them
20Describe the posterior pituitary gland and hypothalamus reltionship.
Connected by the neurophysis - nerve fibres connect them
21What is the hypophyseal portal system?
Pathway through which hormones from the hypothalamus reach the anterior pituitary
22What is Cushing’s syndrome?
When too much cortisol is secreted
23How does Cushing’s syndrome present?
Round moon face; Hump back; Stretch marks; Thin hair; Thin brusises
24What is Cushing’s Disease?
A subset of Cushing’s syndrome caused by too much ATCH secretion
25A pituitary ademona where could lead to bitemporal hemianipoia?
In the optic chiasm
26What does the adrena cortex secrete?
Aldosterone; Cortisol; Androgens
27What does the adrenal medulla secrete?
Noradrenaline; Adrenaline
28What nucleus in the hypothalamus is responsible for ADH secretion?
Supraoptic nucleus
29What nucleus in the hypothalamus is responsible for Oxytocin secretion?
Paraventricular nucleus
30Where are the adrenal glands located?
Superior poles of the kidneys
31What is the shape of the left and right adrenal glands?
The right adrenal gland has a pyrimidal shape; The left adrenal gland has a crescent shape
32What is the function of the adrenal glands?
Secrete hormones in response to stress and metabolism
33What are the two central regions of the adrenal glands?
Adrenal medulla and adrenal cortex
34What are the three zones of the adrenal cortex?
Zone of fasciculata; Zone of glomerulosa; Zone of reticularis
35What is the function of adrenal capsule?
Anchors the adrenal gland to the surrounding tissues; Acts as a barrier between the gland and the surrounding fat and fascia
36What is the hilum of the adrenal glands?
Points of exit of the veins and lympathics which are located within the capsule
37What cells in the adrenal medulla secrete catecholamines?
Chromaffin cells
38What hormones is secreted from the zona glomerulosa?
Aldosterone and other mineralocorticoids
39What hormone is scereted from the zona fasciculata?
Cortisol and other glucocorticoids
40What hormone is secreted frome the zona reticularis?
Androgens
41Describe the nerve supply to the adrenal glands?
Mainly from the coeliac plexus and the thoracic splanchnic nerves
42What arteries supply the adrenal glands?
Superior suprarenal arteries from the inferior phrenic artery; Middle suprarenal artery from the SMA; Inferior suprarenal artery from the renal artery
43Where does lymphatics from the kidney drain into?
Lumbar lymph nodes
44Where does the left and right suprarenal vein drain into?
Right drains into the IVC; Left drains into the left renal vein
45What are the infrahyoid muscles and what are their functions?
Sternohyoid, omohyoid, thyrohyoid and sternothyroid; Depress hyoid
46What is the pretracheal fascia?
Connects the STRAP muscles and the thyroid together
47What is the function of the thyroid gland?
It produces hormones T4,T3 and calcitonin that regulate metabolism, growth and calcium balance
48What is the shape of the thyroid gland?
Butterfly shape
49What is the nerve supply to the thyroid?
C5 to T1
50Describe the special features of the thyroid.
Has a pyrimidal lobe which may extend upwards from the isthmus; Has a capsule which surrounds the gland; Isthmus is a band of tissue connecting the two lobes together
51What is the nerve supply of the thyroid?
Cervical ganglia and vagus nerve
52What hormones does the thyroid produce?
T3,T4 and calcitonin
53What is the ligament of berry?
Ligament which connects the throid to the trachea
54What is the significance of the ligament of berry and tubercle of zuckerandi
Surgical landmark for protecting the recurrent laryngeal nerve
55What is the tubercle of zuckerandi?
Posterior projection of the lateral lobes of the thyroid galnd
56Describe the blood supply to the thyroid.
Superior thyroid artery - branch of the external carotid; Thyroid ima artery - branch of the brachiocephalic trunk; Inferior thyroid artery - branch of the thyrocervical trunk
57Wheres does the superior and middle thyroid veins drain into?
Inferior vena cava
58Where does the inferior thyroid vein drain into?
Branchiocephalic vein
59What is a thyroglossal cycst?
An abnormal cysts that forms in the foramen caecum that moves with the tongue
60What is goitre?
Enalrgement of the thyroid which moves with swallowing
61What is the function of the parathyroid gland?
Produces parathryoid hormone needed in regulation of calcium
62How many parathyroid glands are there?
FOUR
63Where are the parathyroid glands found in relation to the thyroid?
Found on the posterior side of the thyroid
64Describe the primary arterial supply to the parathyroid glands.
Inferior thyroid artery
65Describe the collateral supply to the parathyroid glands.
Superior thyroid artery; Very rarely the thyroid ima artery
66Describe the nerve supply to the parathyroid glands.
Vagus nerve for parasymtpathetic; Cervical ganglia
67What is the function of the pancreas?
Endocrine and exocrine organ which secretes hormones and enzymes
68What vertebral level is the pancreas located at?
L1/L2
69What are the four parts of the pancreas?
Head; Neck; Body; Tail
70What is the uncinate process of the pancreas?
A hook-shaped projection of the pancreatic head that extends posterior to the superior mesenteric vessels
71What is the function of the sphincter of oddi?
Prevents backflow of substances back into the pancreatic or common bile duct
72What is the ampulla of vater?
Connection of thertr the main pancreatic duct and the common bile duct meet
73Describe the blood supply to the pancreas.
Body and Tail is supplied by the splenic artery; Head is supplied by a branch of the gastroduodenal artery
74What vein drains the pancreas?
Splenic veins and superior meseneteric veins
75Describe the nerve supply to the pancreas?
76What does epigastric pain radiating to the back suggest?
Pancreatic issues
77What does steatorrhea suggets?
78What does jaundice suggest?
Blockage in biliary system