1Red muscle fibers
have more myoglobin aka more red blood cells
2fatigable
something like the bicep
3nonfatigable
aka high resistance to fatigue
muscle like the diaphram and the muscles that help with posture
4type 1 characteristics
high resistance to fatigue
low speed of shortenting
moderate specfic tension
5type 2a characterics
high/moderate resistance to fatigue
high speed of shortenting
high specfic tension
6type 2x charactics
low resistance to fatigue
highest speed of shortenting
high specfic tension
7if you want to increase reisistance to fatigue
need more mitochondria
8if you want to increase speed of shortneing
you can do that by sending AP down t tuble faster
9if you want to increase specfic tension
then you can increase the number of mysion heads
10MATPase
affects SPEED of contraction
mysion enzyme that breaks down ATP and ATP hydrolysis is the rate determing step in muscle contraction
11MATPase staning
just measures the level of an enzyme so there is a lot of assumption that have to be made
darker: lower
Lighter: higher levels
12oxidative capacity
aerobic
anaerobic
13SDH staining
it is located in the mito and it is for aerobic
higher contraction of this leads to the capability for a lot of oxidative phosphorylation
dark color means more mito
light color means less mitochondria
GIVE INFO ON RESISTANCE TO FATIGUE (dark color more mito less fatigue)
14alpha GPD staining
is for anaerbic
it is involved in shuttleing a product for glycolysis
dark more glycolysis
light less glycolysis
GIVE INFO ON RESISTANCE TO FATIGUE (dark color more glycolysis more fatigue)
15MHC isoforms
humans have 3
type 1 type 2a and type 2x
green-type 1
orange- type 2a
black-type 2x
gives us a count of how many there are of the diffeent types of fibers
if there are fibers inbettwen color then thos fibers are transitioning from one type to another
16maxium force study
type 2 fibers higher specfic force then type 1
and you need to control size why? if you dont then the number of conractiole proerties (aka myosin and actin) directly affect force production
17strucutral differnce
fast fibers (type 2) can take up 2-3 more volume then slow fibers (type1)
that exta volume is in having increased SR and T tubles allows for quicker initation of contraction
contractile units- similar in mass, shape, and filament spacing
18type 1
low MATPase activity
high SDH activity
L/H aplha GP acitivity
high number of mito
low speed of shortening
moderstae specfic tension
aerobic prodom energy system
high reistance to fatigue
high efficiency
low Ca uptake into SR
19type 2 a
high MATPase activity
high SDH activity
H aplha GP acitivity
high to moderate number of mito
high speed of shortening
high specfic tension
aerobic/ anaerobic prodom energy system
high/ moderate reistance to fatigue
moderate efficiency
high Ca uptake into SR
20type 2x
high MATPase activity
low SDH activity
H aplha GP acitivity
low number of mito
highest speed of shortening
high specfic tension
anaerobic prodom energy system
low reistance to fatigue
low efficiency
high Ca uptake into SR
21motor unit
the alpha motor neuron and all muscle fibers it innervates
22alpha motor neurons
can innervate a few fibers up to hundreds
23innervation ratio
number of muscle fibers innvervated by the motor neuron
24Henneman's Size Principle
measureed the relation between motor neuron electrical activity during streching
when tension increased so did the size of the the motor unit activaed
small MU contain slow fibers (type 1)
large MUs contain fast fibers (type 2)
25general princple of ATP
immediate source can regenerate ATP quickly but have samll reserves
oxidative pathways have extensive reserves but take several seconds to mins to increase ATP production
26immediate system
ATP-CP anaerobic
27short term energy system
glycolysis anaerobic
28longer term engery system
aerobic oxidative phosphorylation
29ATP-CP
creatine kinase reaction
maintains ATP levels
able to reform ATP from ADP as quickly as it is broken down
muscle stores of phosphocreatine
byproduct: creatine supplementation