Arteriosclerosis/ Atherosclerosis

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1
Presence of atheroma’s in large arteries
Atherosclerosis
2
Plaques consisting of lipids and calcium
Atherosclerosis
3
General term for all types of arterial changes including degenerative changes in small arteries and arterioles, loss of elasticity, and narrowing and obstruction of lumen
Arteriosclerosis
4
Damage to the lining of the blood vessel wall can result in plaque formation leading to atherosclerosis. Identify the tissue that lines the blood vessel wall.
Atherosclerosis
5
Name 4 things that can cause damage to lining of the blood vessel resulting in plaque formation
1 high BP
2 cigarette smoke
3 elevated levels of cholesterol and triglyceride in the blood
4 infection and inflamed
6
Name the compound that may be formed when blood cholesterol levels are elevated. This compound damages the lining of blood vessels
Oxidized LDL
7
Briefly, describe how necrotic foam cells are formed
Unable to process oxidized LDL
8
Briefly, describe how necrotic foam cells cause further damage to the lining of blood vessels
Ruptured and oxidized LDL depositedd in blood vessel wall
9
Type of cell that adheres to damaged blood vessel wall
Platelets
10
Cells that release growth factors which result in proliferation of smooth muscle. Proliferation of smooth muscle contributes to blockage of blood vessel
Platelets, macrophages
11
Plaques are accumulations of necrotic foam cells and LDL. What do ruptured plaques form?
Thrombi and emboli
12
Does atherosclerosis increase or decrease blood flow?
Decrease
13
Does atherosclerosis increase or decrease blood pressure?
ncrease
14
Term for decreased blood flow to tissues
Ischemia
15
Condition caused by partial occlusion of a coronary artery

Angina pectoris
16
Condition caused by total occlusion of a coronary artery
Myocardial infraction (MI)
17
Condition caused by partial occlusion of carotid or cerebral arteries. This condition is commonly called a stroke.
Transient ischemic
18
Condition caused by total occlusion of carotid or cerebral arteries
Cerebrovascular accident (CVA)
19
Conditions caused by atherosclerosis in iliac arteries

Peripheral vascular disease
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