1Presence of atheroma’s in large arteries
Atherosclerosis
2Plaques consisting of lipids and calcium
Atherosclerosis
3General term for all types of arterial changes including degenerative changes in small arteries and arterioles, loss of elasticity, and narrowing and obstruction of lumen
Arteriosclerosis
4Damage to the lining of the blood vessel wall can result in plaque formation leading to atherosclerosis. Identify the tissue that lines the blood vessel wall.
Atherosclerosis
5Name 4 things that can cause damage to lining of the blood vessel resulting in plaque formation
1 high BP
2 cigarette smoke
3 elevated levels of cholesterol and triglyceride in the blood
4 infection and inflamed
6Name the compound that may be formed when blood cholesterol levels are elevated. This compound damages the lining of blood vessels
Oxidized LDL
7Briefly, describe how necrotic foam cells are formed
Unable to process oxidized LDL
8Briefly, describe how necrotic foam cells cause further damage to the lining of blood vessels
Ruptured and oxidized LDL depositedd in blood vessel wall
9Type of cell that adheres to damaged blood vessel wall
Platelets
10Cells that release growth factors which result in proliferation of smooth muscle. Proliferation of smooth muscle contributes to blockage of blood vessel
Platelets, macrophages
11Plaques are accumulations of necrotic foam cells and LDL. What do ruptured plaques form?
Thrombi and emboli
12Does atherosclerosis increase or decrease blood flow?
Decrease
13Does atherosclerosis increase or decrease blood pressure?
ncrease
14Term for decreased blood flow to tissues
Ischemia
15Condition caused by partial occlusion of a coronary artery
Angina pectoris
16Condition caused by total occlusion of a coronary artery
Myocardial infraction (MI)
17Condition caused by partial occlusion of carotid or cerebral arteries. This condition is commonly called a stroke.
Transient ischemic
18Condition caused by total occlusion of carotid or cerebral arteries
Cerebrovascular accident (CVA)
19Conditions caused by atherosclerosis in iliac arteries
Peripheral vascular disease