1Disease Classification
Influenza (flu)
2Causative Agent
Influenza Virus
3Classification of the Flu
Multi-strand(8 segments) RNA genome, Virion 80-200nm, Enveloped, Hemagglutinin (HA) Spikes, Neuraminidase (NA) Spikes
4Hemagglutinin Spikes
attach and allow entry into the cell
5Neuraminidase (NA) Spikes
Escape of viruses
6Reservoir
Humans and other vertebrates
7Portal of Entry
Respiratory Tract
8Incubation Period
1-2 days
9Pathogenesis
HA spikes gain entry via ciliated epithelial cells. Viruses replicate and spread to other cells of lower respiratory tract including aleolar cells. damage to mucocillary escalator results in secondary bacterial infections
10Symptoms
fever, cough, sore throat, runny/stuffy nose, body aches, headaches, chills, fatigue, sometimes diarrhea and vomiting. Usually resolve within ONE WEEK
11Symptoms with more serious conditions
Difficulty breathing or shortness of breath, pain/pressur in chest or abdomen, sudden dizziness, confusion, severe or persitant vomiting,
12Complications
Upper respiratory tract infection, ear infections, worsening of asthma or other chronic conditions, pneumonia, inflammation of heart, brain,and kidneys, sepsis, death
13Prevention
everyday preventative measure, wash your hands
14Treatment
Rest, drink fluids, Antivrial drugs- NA inhibitors or M2 inhibitiors