1Opioid receptors are ____, _____, & _____; Making opioids _____ of these.
- Mu, Delta, Kappa
- Agonists
2The principal site in the brain that triggers the onset of opioid withdrawal syndrome is the _______ at the ____ of the brain
- Locus coeruleus
- Base
3Early s/s of opioid withdrawal include _____, _____, _____, and _____.
- Diaphoresis
- Insomnia
- Increased lacrimation (watery eyes)
- Anxiety
4Late s/s of opioid withdrawal include _____, _____, _____, _____, & _____
- Agitation, dilated pupils, nausea, vomiting, and diarrhea
5Fluoxetine is an ____ used to tx _________. It carries the risk of _______ if combined with other substances that also increase serotonin levels like ______
- SSRI
- Generalized anxiety disorder
- Serotonin syndrome
- 3,4-Methylenedioxymethamphetamine (MDMA)
6What are the s/s of serotonin syndrome?
- Tremors, hyperreflexia, a high-grade fever, and marked confusion?
7Anticholinergic overdose presents with a typical anticholinergic toxidrome of " ________, ________, ______, _______, _______, _______"
"hot as a hare, red as a beet, dry as a bone, blind as a bat, mad as a hatter, full as a flask."
8_______ are the most commonly used medications with anticholinergic properties
- Antihistamines (ex. Meclizine for vertigo)
9Majority of Anticholinergic toxicities require what kind of management?
Supportive Care
10________ is the most common long-term sequelae of alkaline caustic injuries to the esophagus
- Stricture of the esophagus