HP252 final

imparied short term memory
imparied long term memory
personailty change
impaired judgement
impaired language
impaired visual recongiton

NOT delirium, schizophreina, or major depression
acquired, persistentm affects several areas of mental function
severe enough to interfere with work social activities and relationships with other
alzheimer's dieases, stroke, parkinsons, etc

about 2% of 65 year ols are ffected by dementia and about 20% of 80 year olds are likey to be affected by dementia
doubles every 5 years in america
incidnece slows with the age becuase individuals die eariler

a slowly degenerating brain disease marked by changes in behavior and personality and by irreversible decline in intellectual abilities thinking memeory and judgement

only diease that cant be cured or slowed or prevented
highest in 75-84
2020 5.8 million american were living with AD
sytpoms can first appear after age 60 and risk increase with age

affect man in women equally but it is more prevalent in women 2/3 of pop women
AD appears twice as high in AA and 1.5 in LA
risk factors are HBP and diabetes but even more so lower access to health care

two hallmark alzheimer lesions observable
amyliod plaques: clumps of protein fragments that accumlate OUTside the cell, tied bundles of proteins the impair the function of neurons
Neurofibrillary tangles: clumps of proteins that are altered INside the cell that deposits accumalte in the brain's blood vessels
common in just aging but are extreme in this dieases

1.) memory loss that disrupts daily life
2) challenges in planning or sloving problems
3) diffculty performing familiar tasks
4) new probelms with words in speaking or writing
5) disorientation to time and place
6) poor or decease judgement
7) probelms with abstract thinking
8) misplacing things and losing ability to retract steps
9) changes in mood or behavior, including apathy and depression
10) withdrawl from work or social activites

greatest known risk factor for developing AD is increasing age (10% for 65 up and 32% for 85up)
genetics (3 genes cause early onset AD and one increases risk of typical onset)
other factors ( high cholestorl, HBP, serious head injury and other congitive disbailities)

90% say talking with loved ones about end of life is important---> 27% actually do it
80% say if they are seriously ill they would talk to doctor about end of life decisions----> 7% have had conversation with doctors
82% say its important to put wishes in writing----> 23% have put wishes in writing

Heart dieases
cancer
COVID (this new)
unintenital injury
stroke
chronic respiratory disease
alzheimer disease
diabetes
flu and pneumonia
kidney disease

it is about planning what measure you would wan taken if something happens and you cant speak for yourself you can even step up how you would want your death/ burial to take place and it can even be to plan who will make those decisions if you arent available

close to death no longer to save the person or cure them
more about a good death
can happen anywhere, need to have less than 6 months
fully convered by medicre
can happend anywhere

not as covered or as avaible typicall only in hospitals
seeking comfort and pain management can have this with curtative treatment still trying to save the life

denial
anger
bargining
depression
accpetance