Pyruvate Oxidation and Citric Acid Cycle

Conversion of pyruvate to acetyl-CoA, producing CO₂ and NADH in mitochondrial matrix.

2-carbon molecule entering the Citric Acid Cycle.

Series of reactions oxidizing acetyl-CoA to CO₂ and producing NADH, FADH₂, and ATP.

Mitochondrial matrix.

4-carbon molecule that combines with acetyl-CoA to start the cycle.

6-carbon compound formed from OAA + acetyl-CoA.

Removal of CO₂ during pyruvate and cycle reactions.

3 NADH, 1 FADH₂, 1 ATP (2 CO₂).

6 NADH, 2 FADH₂, 2 ATP, 4 CO₂.

Generate electron carriers for oxidative phosphorylation.

Direct formation of ATP from ADP and substrate.

Controlled by availability of acetyl-CoA and feedback from NADH/ATP levels.

Inner space where CAC enzymes operate.