1DNA and RNA
Nucleic acids that are long chains of chemical units called nucleotides.
2A necleotide polymer is a
polynucleotide
3How are nucleotides joinged together
By covalent bonds between the sugar of one nucleotide and the phosphate of the next pattern
4Sugar-phosphate backbone
In the next repeating pattern, the next phosphate in the sugar-phosphate-sugar-phosphate.
5Each nucleotide consists of three componets...
1- a nitrogen base, a sugar, and a phosphate group.
6Deoxribose
what sugar is called in DNAand RNA structure because it's missing an oxygen atom.
7The full name for DNA
deoxyribonucleic acid. Nucleic refers to the DNA's location in the nuclei of eukaryotic cells.
8Thymine (T) and cytosine (C) are
single ring structures. one of the 4 DNA nucleotides that differ intheir nitrognout bases
9Adenine (A) and guanine (G) are
larger, double ring structures. one of the 4 DNA nucleotides that differ intheir nitrognout bases
10RNA has Uracil (U) and contains what different sugar compares to DNA
ribose.
11Double helix
determined by James WAtson and Francis Crick. a helix with a uniform diameter made up of 2 polynucleotide strands.
12DNA polymerases
emzymes that make covalent bonds between the nucleotides of a new DNA strand and help repair DNA that is damaged by toxic chemicals or high enegry radiation.
13Sites where DNA replicantion begins on a double helix
orgins of replication. Then proceeds in both directions, creating replication "bubbles"
14What does DNA replicaation ensure
that all body cells in a multicellular organism carry the same genetic information. Genetic information is passed along to offspring.
15DNA specifies the synthesis of protiens in...
transcription- the transfer of genetic information from DNA into an RNA molecule
Translation- the transfer of information from RNA into a polypeptide.
16The function of the DNA gene is to dicatate
the production of a polypeptide.
17codons
the instructions of the amino acid sequence of a polypeptide chain are writtten in DNA and RNA as a series of three base words.
18RNA codons are translates into...
amino acids that form a polypeptides.
19Transcription
is the transfer of genetic information from DNA to RNA.
20The nucleotides that make up the new RNA molecule...
take their place at a time along the RNA template strand by forming hydrogen bonds with the nucleotide bases there.
21RNA polymerase
the RNA nucleotides are linked by the transcription enzyme.
22What is a tRNA molecule made out
a strand of RNA about 80 nucleotides, twisted and folded upon itself.
23Anticodon
the end of the tRNA that is a special triplet of base.
24When the anticodon on the tRNA recognizes a particular codon on the mRNA by using base-pairing rules.
During translation.
25the other end of the tRNA molecule is
the site where one kind of amino acid attaches
26Translation is divided into the same three phases as transcription
initiation, elongation, and termination.
27Initiation occurs in 2 steps
1- an mRNA molecule binds to a small ribosomal subunit, then a initiator beinds to start condon, where translation is to begin on the mRNA.
2- a large ribosomal subunit binds to the small one, creating a functional ribosome.
28Enlongation contiunes until
- a stop codon reaches the ribosome's A site, the completed polypeptide is freed, and the ribosome splits back into its subunits.
29Mutation
any change in the nucleotide sequence of a cell's DNA.
30Mutations can involve...
a large regions of chromosome of just a single nucleotide pair.
31Mutations in a gene can be divided into 2 general cateogories.
1- nucleeotide substitutions and
2- nucleotides insertions or deletions.
32Bacteriophages or phages for short
viruses that attack bacteria (bacteria eater)
33The phage consists of a
molecule of DNA enclosed within an elaborate structure made of proteins.
34Once they infect bacterium most phages enter a reproductive cycle called
lytic cycle
35Lysogenic cycle
an alternative route, in which viral DNA replication occurs without phage production of the death of the new cell.