Meiosis

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1
What is mitosis
division of a nucleus
2
what is binary fission
division of prokaryotic cells
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what is a similarity between mitosis and binary fission
they are two processes that produce daughter cells identical to the parent cell
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What is meiosis
produces daughter cells with half of the DNA of the parent cell
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what are gametes
cells produced by meiosis
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mitosis vs meiosis
meiosis goes through cell div twice while mitosis does only once; in meiosis you have 4 daughter cells while in mitosis u only have two; mitosis takes places in organs and tissues while meisosis takes place in reproductive organs; number of chromosomes in daughter cells in mitosiss is 2n and in meiosis is n; homologous chromosomes divide in meisis but not in mitosis
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what is nondisjunction
the failure of homologuous chromosomes to separate in either meiosis i or in meiosis ii
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what is the principle of independent assortment
different genes assort (passed into gameter) independentl ybceuse they are located on diferent chomromsomes which align randomly at the metaphase plate during meisois i
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what is chrossing over
when homologous chromosomes exchange segments of dna at cross over sites called chiasmata
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what is chiasmata
when dna crosses over
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when does dna replication take place
interphase
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when are tetrads formed
prophase 1
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what are tetrads
four sister chromatids
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how many cells an be used for males in habloids
4/4
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how many cells an be used for females in habloids
1/4
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diploid
having homologous pairs/two copies of each chromosome
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haploid
having one copy of each chromosome
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what are the steps in meiosis 1
prosphase 1, metaphase 1, anaphase 1, telophase 1 and cytokinesis
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what is the steps in meiosis 2
prophase 2, metaphase 2, anaphase 2, telophase 2 and cytokinesis
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where does meiosis happen
reproductive organs
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number of nuclear divisions in meiosis
2
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number of daughter cells formed in meiosis
4
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do homologous chromosomes divide
Yes
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do sister chromatids divide
yes
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does crossover happens
yes
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what is tetrad
in prophase 1, replicated homolous chromosome join to form a structure called a tetrad. tetra means 4, 2 replicated chromosomes in a total of 4 sister chromatids
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what is chiasmata
series of 4 sister chromatids (2 for each chromosome in the homologous pair) that overlaps at areas
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what is synapsis
when homologous chromsosmes pair up during propahse 1
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what does crossing over result in
recombination of alleles from one individual
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why is crossing over inmportant
it maxes the variety in gametes produced, which results in variety in offpring
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what is trisomy 21
3 chromosome 21
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explain how failure to separate chromosomes during gametes creation (or nondisjunction) in one of the parents of the person resulted in them having this arrangement
if one parent has a gamete that has experienced nondisjunction, it contains two copies of chromosome 21 instead of 1. when joined with the other gamete this is total of 3 chromosome 21
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who gregor mendel
he conducted experiments with pea plants to provide evidence for inheritance of dominat and recessive traits
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Who is reginald punnett
he provided a helpful tool for evaluating probablility of this inheritance ith the punnett square
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what are different forms of a trait called
alleles
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two forms of a trait that we can exhibit are found
on homologous chromosomes
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how are dominant alleles represented
uppercase
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how are recessive alleles represent
lowercase
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AA is what genotype
homozygous
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Aa is what genotype
heterozygous
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aa is what genotype
homozygous
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difference between genotype and phenotype
genotypes are the genes or combinations of alleles that an organism has. the phenotype is the physical trait or observable expression of the trait that we see as the result of the genotypes
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how many alleles fr each gene are in a haploid cell
1
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describe how the creation of haploid cells by meiosis (gametes) in sexually reporducing organisms is essential to create a diploid zygote
when haploid gametes combine, the offspring will have a diploid number of chromosomes with one allele from each parent
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why use capital letters with codominant alleles?
lowercase letters typically represent recessive traits.
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what does codominance mean
if no traits are recessive to each other, it make more sense for both to be represented wtih uppercase letters as both are dominant.
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NAME ALL THE BLOOD TYPES
AB+ , A+, B+, O+, AB-, A-, B-, O-
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human blood type is determined by alleles:
I(A), I(B), i, Rh+,Rh-
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Why do we use "i" to represent the blood type O phenotype
i is recessive to I(A) and I(B) -- in fact, it is the only recessive allele for blood type because it does not code for any antigens
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is O, A, B, and AB pheno or geno
Phenotype
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How is blood type AB an example o codominance
both A and B antigens are present on RBCs
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Is ii, I(a), I(B), a pheno or geno
genotype
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geno of O
ii
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Geno of A
I(A)I(A) or I(A)i
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Geno of B
I(B)I(B) or I(B)i
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geno of AB
I(A)I(B)
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RECESSIVE TRAITS are found on which sex chromosomes
X
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Sqaures on pedigrees are which gender
male
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circle on pedigrees are which gender
female
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shaded sqare =
affected male
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half shaded circle
carrier female
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Alleles carried on the x chromosome are represented as a...
superscript next to an uppercase X (X(H))
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Recessive traits found on the X chromosome are more common in people who are... why?
male because they have only one copy of that gene (one X) only one allele to determine that phenotype
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what is polygenic traits
traits controlled by multiple genes
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polygenic traits creates more/less variation in phenotype
more
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what is a pedigree
an extra simplified biologial family tree
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what is pedigrees used for
to track one trait over many gen
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in a pedigree, if there are any affected individuals who have unaffected parents the trait is
the trait is recessive
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in a pedigree if each affected individual has at least one affected parent, the trait is
dominant
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in a pedigree if there are more affected males than females, it may be a .... trait
sex linked recessive trait
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what are recombinant genes
genotypes that are different from parents
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how to get more recombinants in a linked gene
when gene is further apart on chromosome
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what is test cross
crossing with a homozygous recessive for both traits
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what is linkage group
a group of genes whose loci are on the same chromosome and don't not independently assort
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if genes are unlinked...
genes are on different chromosomes, iherited independently, and should follow the 9:3:3:1 ratio
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what is the chi square
a test to find differences observed are due to chance or linked
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what is the chi square eq
x^2= sigma [(O-E)^2/(E)]
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Define terms in chi square eq
O is observed value, sigma = sum, e = expected (or predicted) value
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in chi square, what are expected results in form of?
punnet swaures
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what is steps in chi sqaure
1) create hypothesis
2) calc the chi swaure
3) look up critival value fro mtable
4) compare act results with predicted
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what is degrees of freedom
number of outcomes minus one
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what is critical value
it is a point on the graph where its labelled 0.05. and there's a number below it
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if the calculated value is larger than crit value?
reject ur null hypothesis
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if the calculated value is smaller than crit value?
accept ur null hypothesis
85
what is null hypothesis
theorizing that there is no sig difference between observed and expected results
86
where are mutations found with someone heterozygous for sickle cell anemia
in brain cells
87
in a human with type A blood, what determines their blood group
multiple alleles
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