1What is CNS and PNS?
Central nervous system and peripheral nervou system.
Central nervous system is spinal cord and brain&brain stem.
Peripheral nervous system is connection to outside world.
2What are the targets for the ANS?
Cardiac and smooth muscles, Glands (Exocrine and Endocrine)
3What are the targets for the SNS?
Skeletal muscle
4What branches from Peripheral Nervous System?
Autonomic nervous system - Involuntary and smooth and cardiac muscle.
Somatic nervous system - Voluntary and skeletal muscle.
5What is pns and sns?
Branches from Autonomic nervous system.
* Parasympathetic nervous system - rest and digest, inables emptying of bladder, food digestion, housekeeping or calming.
* Sympathetic nervous system - Fight or flight response, inhibits urination, pupils dilate, inhibits digestion, increase glycose conversion.
6What neurotransmitters does Sympathetic preganglions release or use:
Acetocholine
7What neurotransmitters do Sympathetic postganglions release or use:
Norepinephrine and epinephrine
8What neurotransmitters do Parasympathetic preganglions release or use:
Acetocholine
9What neurotransmitters do Parasympathetic postganglions release or use:
Acetocholine
10Name the 2 Cholinegeric receptors:
Nicotinic -
ANS postganglionic neurons
Opens nonspecific cation channels
Influx of Na+ than efflux of K+
Depolarization to threshold
Motor end plates of skeletal muscle
Some CNS
Muscarinic -
Effector cell membranes
Smooth and cardiac and glands
5 subtypes of receptors
G-protein linked second messenger system.
11What are the 2 types of Adrenergic receptors?
Alpha and Beta receptors
12Alpha 1
Present in most sns tissue
Ca++ second messenger system
Generally excitatory to target organ
13Beta 1
Binds to NE and Epi equally
Primarily in the heart
Generally excitatory response
cAMP second messenger system
14Beta 2
Binds to Epi preferably
Smooth muscle of arteries and airways
Generally inhibitory response
cAMP second messenger system
15Alpha 2
cAMP second messenger system
Generally inhibitory to target organ