Nervous System

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1
What is CNS and PNS?
Central nervous system and peripheral nervou system.
Central nervous system is spinal cord and brain&brain stem.
Peripheral nervous system is connection to outside world.
2
What are the targets for the ANS?
Cardiac and smooth muscles, Glands (Exocrine and Endocrine)
3
What are the targets for the SNS?
Skeletal muscle
4
What branches from Peripheral Nervous System?
Autonomic nervous system - Involuntary and smooth and cardiac muscle.
Somatic nervous system - Voluntary and skeletal muscle.
5
What is pns and sns?
Branches from Autonomic nervous system.
* Parasympathetic nervous system - rest and digest, inables emptying of bladder, food digestion, housekeeping or calming.
* Sympathetic nervous system - Fight or flight response, inhibits urination, pupils dilate, inhibits digestion, increase glycose conversion.
6
What neurotransmitters does Sympathetic preganglions release or use:
Acetocholine
7
What neurotransmitters do Sympathetic postganglions release or use:
Norepinephrine and epinephrine
8
What neurotransmitters do Parasympathetic preganglions release or use:
Acetocholine
9
What neurotransmitters do Parasympathetic postganglions release or use:
Acetocholine
10
Name the 2 Cholinegeric receptors:
Nicotinic -
ANS postganglionic neurons
Opens nonspecific cation channels
Influx of Na+ than efflux of K+
Depolarization to threshold
Motor end plates of skeletal muscle
Some CNS
Muscarinic -
Effector cell membranes
Smooth and cardiac and glands
5 subtypes of receptors
G-protein linked second messenger system.
11
What are the 2 types of Adrenergic receptors?
Alpha and Beta receptors
12
Alpha 1
Present in most sns tissue
Ca++ second messenger system
Generally excitatory to target organ
13
Beta 1
Binds to NE and Epi equally
Primarily in the heart
Generally excitatory response
cAMP second messenger system
14
Beta 2
Binds to Epi preferably
Smooth muscle of arteries and airways
Generally inhibitory response
cAMP second messenger system
15
Alpha 2
cAMP second messenger system
Generally inhibitory to target organ
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