Exam 4 Crossword Study Guide

A 10% solution of potassium ___ is commonly used to detect fungal elements in dermatological and other specimens by direct light microscopy

The anti-dermatophyte agent grisofulvin inhibits mitosis by binding to fungal ___

What is the dermatophyte species of Tricophyton that typically produces no macroconidia, no microconidia, but produces hyphal favic chandeliers or nail head tips in the mycelium?

What is the most widesread genus among the anthropophillic dermatophytes?

During broth dilution antifungal suseptibility testing, a ___ effect occurs when the combination of compounts results in an increase in inhibitory activity.

Members of what genus are cosmopolitan, very common saprobes, mostly found in soil, and many species are keratinophiles? isolates may be confused with dermatophytes

What is the dermatophytic genus that in vitro, produces macroconidia and abundant chlamydospores in mature colonies, but lacks microconidia?

Zoophilic isolates of Trichophyton ___ are readily contacted by animal handlers and are then associated with inflammmatory lesions of the scalp, glabrous skin, nail area, and beard region.

The anti-dermatophyte agent griseofuvin binds to ___ and is concentrated in skin precursor cells.

An ___conidium is liberated after release of a supporting cell

Potato glucose (dextrose) agar or conrmeal agar favors/promotes the production of red pigment on the reverse of the majority of isolates of what Trichophyton species that remain unpigmented on Sabouraud agar?

Trichophyton schoenleinii is the etiologic agent of Tinea ___, a chronic infection that is a severe form of tinea capitus and is characterized by the production of scutula.

___ was discovered from the soil fungus Penicillium griseofulvum, and is on the Word Health Organization's List of Essentail Medicines.

Anthropophillic isolates of Trichophyton mentagrophytes complex largely now belong to the moleculary redfined species T. ___, and are a frequent cuse of chronic infection of the feet, nails, and inguinal areas.

What group of antifungal agents interact with the fungal cell membrane sterols physiochemically?

Echinocandins inhibits fungal cell wall by inhibiting the ___ of the β-1, 3-glycan protein, via inhibiting 1,3 β-glucan synthase.

Microsporum ___ must be distinguished from Trichothecium, a cosmopolitan, saprobic fungal genus, during identification of an isolate.

What is the small ciruclar membrane attached at the base of a free conidium? This strucutre is a vestage of the conidiophore.

Microsporum ___ is the most common dermatophyte isolated from cats and this fungis produces abundant, fusoid macroconidia in vitro.

What are the four genera of dermatophytes?

Tinea ___ is dermatophytosis of the feet. This infection is characterisitcally occult, thus carriers exist.

Tinea ___ is dermatophytosis of the scalp. This infection is highly aggressive and cannot be treated topically

Tinea ___ is dermatophytosis of the body. This infection is frequently found in dogs, cats, and pigs.

Tinea ___ is dermatophytosis of the hands.

Tinea ___ is dermatophytosis of the nail and is often the most difficult tinea infection to treat.

Tinea ___ is dermatophytosis of the inguinal area.

What layer of the epidermis do dermatophytes most often infect?

What is the name of the border on a hair follicle where dermatophytes are able to germinate and proliferate?

___ spores are external to the hair follicle, while ___ spores are internal to the hair follicle.

Calcaflour white is a flourescent stain that is attracted to what fungal cell wall component?

What process is used to differentiate Trychophyton rubrum and T. mentagrophyte in vitro?

What is the fungal cell wall component that azole-based, polyene, and allylamine fungicides attack?

What is the polyene antifungal drug that is concidered the "gold standard", regardless of its intense side affects?

Which enzyme do the Azole fungicides inhibit?

What susprising antibacterial (that has no antimycotic affects) is highly synergistic with Amphoteracin B?

What molecule in the Ergosterol synthesis pathway do the Allylamine fungicides target?

What molecule in the Ergosterol synthesis pathway do the azole fungicides target?

Echinocandins inhibit ___, which induces lysis/apoptosis in the fungal cell

What structure in the cell membrane and fungal wall does Amphotericin B produce which allows its anti fungal properties?

Which antimicrobial suseptaibility methods allow Minimum Inhibitory Concentrations (MIC) to be calculated?