1Taxanes ("taxel"): drugs
- docetaxel (Taxotere) [breast]
- abraxane
- paclitaxel (Taxol/AC-T) [breast]
2Alkylating Agents: drugs
- cisplatin [leukemia]
- cyclophosphamide [breast]
3Antimetabolites: drugs
- methrotrexate [leukemia]
- 5-Fluororacil (5-FU) [breast]
4Antitumor Antibiotics/Anthracyclines ("cin"): drugs
- idarubicin [leukemia]
- daunorubicin [leukemia]
- dactinomycin [leukemia]
- doxorubicin
- (Adriamycin) [breast]
5Antimiotic/Mitosis inhibitors: drugs
- vincristine (bone marrow sparing, for children) [leukemia]
6Taxanes ("taxel"): adverse effects
- skin toxicities
- liver failure
- neuropathies
7Alkylaying Agents: adverse effects
- cisplatin:
tinnitus, ototoxicity, nephrotoxicity
- cyclophosphamide:
alopecia, hemorrhagic cystitis (bladder inflammation & bleeding)
8Antimetabolics: adverse effects
- hepatotoxicity
- photosensitivity
9Antitumor Antibiotics/Anthracyclines: adverse effects
- cardiac & pulmonary toxicity
- vesicants, can cause severe tissue damage w/ extravagation
10Antimitotic/Mitosis inhibitors: adverse effects
- neurotoxicity (numbness, tingling in fingers/toes)
- constipation