1Examples of Direct and Indirect Transmission
2types of transmission in vectors examples
1- Propagative
2- cyclo propagative
3- cyclo developmental
4- transovarial
5-transstadial
3Antropozoonoses-
Zooanthroponoses-
Amphixenosis -
5age of distribution of disease
Typhoid -
measles -
chicken pox-
rubella -
diphtheria-
10-19yr
6mon-6yr
1-10yr
3-10yr (developing) >15yr developed
<5yr
7Disease —
control is to
elimination is to
eradication is when
decrease burden
decrease local transmission
Globally organism is absent
8diseases eliminated in India
and eradicated in world
9endemic is when -
hyper endemic is when -
holo endemic is when-
disease is constant
disease increase at all age groups
disease increase in children
10AFP (Acute Flaccid Paralysis) surveillance criteria and indicators
and NATIONAL POLIO SURVEILLANCE PROGRAM basic
P 1,2,3 strains
11polio free status in
India achieved on (not eradicated)
27 march 2014
12third dose of fIPV introduced on
1 Jan 2023
16Hills criteria for disease causation
1-most difficult
2- most important
1-specificity
2-temporality
17best to eliminate known confounder
matching
18best to eliminate known and unknown confounder
RSSR
randomisation
stratification
stratified randomisation (overall best )
regression/ restriction
Multivariate analysis
19best to eliminate
Bias -
confounding-
blinding (double is most common, triple is best )
randomisation
20types of bias
1)selection-
2)recall-
3)Berksonian-
4)attrition-
5)hawthorne-
6)pygmalion-
7)neyman/survival/incidence prevalence-