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m1 autonomic

95 flashcardsby Philip
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1
2 parts of autonomics
cholinergic and adrenergic
2
what is the blue part
van der waals binding regions for antagonist
3
what is red part
acetylcholine binding site
4
where is the point of attack of metabolism
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6
Alpha agonist
Beta agonist
Selective alpha 1 blocker
Non selective beta blocker
Selective beta 1 blocker
selective bet 1
7
Alpha agonist
Beta agonist
Selective alpha 1 blocker
Non selective beta blocker
Selective beta 1 blocker
selec bet 1
8
Alpha agonist
Beta agonist
Selective alpha 1 blocker
Non selective beta blocker
Selective beta 1 blocker
selec beta 1
9
Alpha agonist
Beta agonist
Selective alpha 1 blocker
Non selective beta blocker
Selective beta 1 blocker
selec beta 1
10
Alpha agonist
Beta agonist
Selective alpha 1 blocker
Non selective beta blocker
Selective beta 1 blocker
select beta 1
11
Alpha agonist
Beta agonist
Selective alpha 1 blocker
Non selective beta blocker
Selective beta 1 blocker
selec beta 1
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13
heart
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a
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prototype of beta blocker
pronethalol
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2nd beta blocker
pronethalol
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propranolol chemical family
aryloxypropanolamines
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major metabolite of propranolol
napthoxylactic acid
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Alpha agonist
Beta agonist
Selective alpha 1 blocker
Non selective beta blocker
Selective beta 1 blocker
nonsel
22
Alpha agonist
Beta agonist
Selective alpha 1 blocker
Non selective beta blocker
Selective beta 1 blocker
non
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Alpha agonist
Beta agonist
Selective alpha 1 blocker
Non selective beta blocker
Selective beta 1 blocker
non sele
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Alpha agonist
Beta agonist
Selective alpha 1 blocker
Non selective beta blocker
Selective beta 1 blocker
nonsele
25
Alpha agonist
Beta agonist
Selective alpha 1 blocker
Non selective beta blocker
Selective beta 1 blocker
beta
26
Alpha agonist
Beta agonist
Selective alpha 1 blocker
Non selective beta blocker
Selective beta 1 blocker
beta agonist
27
Alpha agonist
Beta agonist
Selective alpha 1 blocker
Non selective beta blocker
Selective beta 1 blocker
selec a
28
Alpha agonist
Beta agonist
Selective alpha 1 blocker
Non selective beta blocker
Selective beta 1 blocker
select a
29
Alpha agonist
Beta agonist
Selective alpha 1 blocker
Non selective beta blocker
Selective beta 1 blocker
selec a
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what is the red one
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what is the green one
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1st beta blocker
dichlorisoproterenol
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thymic tumore in mice
dichlorisoproterenol
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Alpha receptor binding site
Betareceptor binding site
beta
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Alpha receptor binding site
Betareceptor binding site
alpha
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COMP OR MAO
mao
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COMP OR MAO
Compt
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Alpha agonist
Alpha 1, beta 1&2 agonist
Selective beta 2 agonist
beta 1&2 agonist
select
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Alpha agonist
Alpha 1, beta 1&2 agonist
Selective beta 2 agonist
beta 1&2 agonist
1&2 agoni
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Alpha agonist
Alpha 1, beta 1&2 agonist
Selective beta 2 agonist
beta 1&2 agonist
alpha , beta 1&2
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Alpha agonist
Alpha 1, beta 1&2 agonist
Selective beta 2 agonist
beta 1&2 agonist
alpha
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Alpha agonist
Beta agonist
Selective alpha 1 blocker
Non selective beta blocker
alpha
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Alpha agonist
Beta agonist
Selective alpha 1 blocker
Non selective beta blocker
alpha
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2 parts of cholinergic receptor
muscarinic and nicotinic
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what is the red one
ammonium binding moeities
50
what is the blue one
hydrogen bond accepting moeities
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acetylcholine bind in muscarinic or nicotinic to mimics what
poop and urine
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stimulates muscarinic receptors
direct acting cholinergic agonist
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blocks acetylcholine esterase
indirect acting cholinergic agonist
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promotes acetylcholine binding and effects
indirect acting cholinergic agonist
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is indirect acting cholinergic agonist reversible or irreversible
both
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where does covalent bonding to enzyme happens in indirect acting cholinergic agonist, reversible or irreversible
irreversible
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is essential for intrinsic activity and contributes to the affinity of the molecule for the receptors.
acetylcholine, oninum group
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in SAR of acetylcholine what does higher alkyl group do
inactivated
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in SAR of acetylcholine what does ethylated do
antagonistic
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in SAR of acetylcholine what does hydrogen do
loss of activity
61
name and state if where it belongs
carbachol, direct acting cholinergic agonist
62
name and state if where it belongs
acetylcholine, direct acting cholinergic agonist
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name and state if where it belongs
methacholine chloride ,direct acting cholinergic agonist
64
name and state if where it belongs
bethanechol chloride, direct acting cholinergic agonist
65
name and state if where it belongs
neostogmine bromide, indirect acting cholinergic agonist, reversible inhibitor
66
name and state if where it belongs
endrophonium chloride indirect acting cholinergic agonist, reversible inhibitor
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name and state if where it belongs
pyridostigmine bromide indirect acting cholinergic agonist, reversible inhibitor
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name and state if where it belongs
sarin ,indirect acting cholinergic agonist, irreversible inhibitor
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name and state if where it belongs
isoflourphate, indirect acting cholinergic agonist, irreversible inhibitor
70
name and state if where it belongs
echothiophate iodide, indirect acting cholinergic agonist, irreversible inhibitor
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which is more stable
upper right
72
These chemicals are nerve poisons and have been used in warfare, in bioterrorism, and as agricultural insecticides
organophosphate ester
73
if the drug is nicotinic blocker it is
muscle relexant
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muscarinic blocker
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76
what does green mean
77
what does blue mean
78
what does violet mean
79
ipratropium , Antimuscarinic
Nicotinic blockers
InDirect acting cholinergic agonist
Direct acting cholinergic agonist
antimuscari
80
scopalamine. Antimuscarinic
Nicotinic blockers
InDirect acting cholinergic agonist
Direct acting cholinergic agonist
antimus
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tiotropium. Antimuscarinic
Nicotinic blockers
InDirect acting cholinergic agonist
Direct acting cholinergic agonist
antimuscarni
82
trihexyphenidyl. Antimuscarinic
Nicotinic blockers
InDirect acting cholinergic agonist
Direct acting cholinergic agonist
antimusca
83
atropine. Antimuscarinic
Nicotinic blockers
InDirect acting cholinergic agonist
Direct acting cholinergic agonist
antimusca
84
benztropine. Antimuscarinic
Nicotinic blockers
InDirect acting cholinergic agonist
Direct acting cholinergic agonist
antimusca
85
Antimuscarinic
Nicotinic blockers
InDirect acting cholinergic agonist
Direct acting cholinergic agonist
nicotinic
86
succinycholine. Antimuscarinic
Nicotinic blockers
InDirect acting cholinergic agonist
Direct acting cholinergic agonist
nicotinic
87
atracurium. Antimuscarinic
Nicotinic blockers
InDirect acting cholinergic agonist
Direct acting cholinergic agonist
nicotini
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cistracurium. Antimuscarinic
Nicotinic blockers
InDirect acting cholinergic agonist
Direct acting cholinergic agonist
nicotinic
89
pancuronium. Antimuscarinic
Nicotinic blockers
InDirect acting cholinergic agonist
Direct acting cholinergic agonist
nico
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vecuronium Antimuscarinic
Nicotinic blockers
InDirect acting cholinergic agonist
Direct acting cholinergic agonist
nicotinic
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vecuronium state of depolarizing or non depolarizing
non de
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pancuronium state of depolarizing or non depolarizing
non dep
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astracorium state of depolarizing or non depolarizing
non depo
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cistracurium state of depolarizing or non depolarizing
non depo
95
succinylcholine state of depolarizing or non depolarizing
depo
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