1Intestional infection is aka?
*Gastroenteritis
2Causative organism of Gastroenteritis?
*Escherichia coli
3Appreviation for Escherichia coli?
E. coli
4E. coli stands for?
*Escherichia coli
5How many pathogenic variants of Eschericia coli?
6
6What toxin is produced by the special type of E. coli?
*shiga toxin
7What Escherichia coli produces shiga toxin?
*E. coli 0157: H7 (STEC)
8What does (STEC) mean?
Shiga toxin-producing E. coli
9Characteristics of Escherichia coli?
*gram negative bacillus
*facultative anarobe (happy with or without oxygen)
*motile
*non-spore forming
10Epidemiology of E. coli gastroenteritis?
*reservoir: animals and their environment
*portal of entry: digestive tract
*mode of transmission: fecal-oral root
11Incubation period of E. coli gastroenteritis?
1-3 dys
12What is the general pathogenesis of E. coli?
*colonization of small/large intestine by attaching to/invading epithelial cells
13Pathogenesis of 0157: H7?
attatches to linning of the colon and forms diarrhea inducing lesions
*can secrete shiga toxins
14What harm do shiga toxins do?
*damage blood vesseles, results in intestional hemmorrhage
15Signs and symptoms of Escherichia coli?
*diarrhea (often bloody, no pus)
*abdominal cramps
*fever
*nausea
*vomiting
16How fast does it take to get better after E.coli?
3-10 dys
17Complications of E. coli?
*severe dehydration
*hemolytic-uremic syndrome (HUS)