Endo Wrap Up

The Anterior Pituitary gland (adenohypophysis) _______ & _______ hormones

The Posterior pituitary gland (neurohypophysis) _____ & _____ hormones

The Anterior Pituitary gland produces/secretes which hormones?

The Posterior Pituitary gland store & releases which hormones?

Endocrine Gland Hormones include...

Downregulation -> prolonged excessive stimulation -> reduced response (lower sensitivity, fewer receptors)

Upregulation -> reduced stimulation -> attempted increased response (higher sensitivity, more receptors)

Primary Endocrine Disorder – dysfunction of the _______

Secondary Endocrine Disorder – dysfunction of ______ caused by abnormal ______ activity

Endocrine Disorders are disorders involving _____, _______, or _______

Tertiary Endocrine Disorder – dysfunction caused by _______ origin

Growth hormone treatment/dosing

Hydrocortisone treatment/dosing

Fludrocortisone treatment/dosing

Levothyroxine treatment/dosing

Estrogen or Testosterone treatment/dosing

DDAVP (Desmopressin) treatment/dosing

Most common cause of Hyperpituitarism

Hyperpituitarism presentation in children

Early: Central Precocious Puberty diagnosis is __________ testing; Treat with _____ agonist including _____, ______, or _____; Developmental delay allow then _____, _____, or ______

Late (Delayed) or Absent (Hypogonadal Hypogonadism) puberty teat with _________; ______ or _______

Antidiuretic Hormone (ADH) Compels the kidneys to......

Central DI is the _______. It can be caused by _____, ______, or ______

Nephrogenic DI is when the kidneys ______. It can be caused by _______, ______, _______, or ______

Syndrome of Inappropriate Antidiuretic Hormone (SIADH) is _______ leading to ______; It is caused by ______, ______, or ______

Cerebral Salt Wasting is when a ________ leads to inappropriate & excessive _______ secretion leading to ______ & _____. Usually occurs ______. Tx includes _____

T4 (thyroxine) – regulates _______ and effects almost EVERY organ system

Hypothyroidism- Underactive, nonfunctional, or absent thyroid gland: will have _____ levels of T3 & T4; Measured by _____

Central Hypothyroidism occurs when _________; TSH levels are _____ & FreeT4 levels are _____

Congenital Hypothyroidism occurs when _______; TSH levels are _____ & FreeT4 levels are _____

Autoimmune Hypothyroidism occurs when _______; TSH levels are _____ & FreeT4 levels are _____

In Subclinical Hypothyroidism TSH levels are _____ & FreeT4 levels are _____

Hashimoto’s Thyroiditis is the Most common cause of _____

Hashimoto’s Thyroiditis will have _____ & _____ present indicating _____. Common in children with _____

Myxedema is severe _____ crisis d/t _______. It causes life-threatening _______, _______, & ______

Congenital hypothyroidism needs to be treated within _____ days of life or sooner

Most common cause of Hyperthyroidism is ________ = ________

Grave’s Disease- Thyroid-stimulating immunoglobulins (TSI) antibodies activate _____ receptors resulting in ______

Thyrotoxic Crisis: Thyroid Storm is a medical emergency leading to ______ & ______

Thyroid Storm Treatment – __________, ________, and surgery

Single thyroid nodule= _______ Multiple nodules = _______

Increased Risk of Malignancy of thyroid nodules seen with ______, _______, ______, ______, _______

PTH breaks down _____ to increase ______

Hypoparathroidism leads to ______; Treatment includes _____ & ______

Hyperparathyroidism leads to ______; The main cause is _____

General Lipid guidlines: LDL >160 means likely ________; LDL >190 means ______

Diabetic Lipid guidelines: LDL >160 in T1DM: _____; LDL >130 in T1DM + risk factor: _______; LDL >130 in T2DM: _______

Hypoparathyroidism leads to ______

Chvostek sign

Trousseaus sign