1Disease Classification
Lime disease, spirochetal infection
2Causative Organism
Borellia burgdorferi
3Get to know your Causative organism
Spirochete, weak gram negative, microaerobic, motile, slow growing
4Epidemiology: Reservoir
Ticks and other animals (deer)
5Epidemiology: Portal of Entry
Epidermis
6Epidemiology: Mode of Transmission
Artropod vector (black legged deer) Tick Bite 36-48hrs duration
7Incubation Period
3-30 days
8Pathogenesis
Spirochete injected into the skin multiply and spread radially- eventually entering lymphatic and circulaotry system to spread through the body. Chronic spirochete infection and immune response damage tissue
9Signs and Symptoms Early- (3-30 days post bite)
Erythema Migran (bull’s-eye rash- presesnt in 80% of cases), fever, chills, headache, fatigue, muscle and joint aches, and swollen lymph nodes
10Complications (days to months post tick bite)
Where bacteria ends is where pain will be: severe headaches, neck stiffness, additional em rashes, arthritis w/painful and swollen joints, facial palsy, intermittent pain in tendons, muscles, joints, and bones, heart palpitations/irregular heart beat, episodes of dizzness or shortness of breath, nerve pain, inflammation of brain and spinal cord, probelms with short term memory, shooting pains, numbness, or tingling in hands or feet
11Prevention
Avoid Ticks- .5% permethrin or 20% deet
12Treatment
Doxycycline, Amoxicillin, Cefuroxime axetil, disulfiram