1Pre-diabetes is classified as a HgbA1C >____% but less than ___%
- 5.7%
- 6.5 %
2Pre-diabetes treatment: Lifestyle modifications: diet and exercise and ______ PO daily
- Metformin: 500-2000mg
3Metformin dose and side effects
- Dose 500-2000mg PO daily
- SE: Diarrhea and abd. pain
4Type 2 DM is classified as a HgbA1C > _____
- 6.5% x2
5Type 2 DM treatment: Lifestyle modifications: diet and exercise, ______ PO daily, ______ & _____
- Metformin: 500-2000mg
- GLP1 & SGLT2
6GLP1 (-glutide): exerts its main effect by stimulating _______ release from the pancreatic islets. It has also been shown to _______, inhibit inappropriate _______ release, and reduce ______
- glucose-dependent insulin
- slow gastric emptying
- post-meal glucagon
- food intake
7SGLT2: (-gliflozins, -flozins): block _____, leading to _______. The advantages of this approach are reduced hyperglycemia without hypoglycemia, along with weight loss and blood pressure reduction
- glucose reabsorption
- urinary glucose excretion
8Glucagon is the counter-regulatory hormone to insulin thats produced by the _____ of the ______
- alpha-cell
-Islets of Langerhans.
9Insulin stimulates ______ aka _____
- Glucose uptake
- Glycogenesis
10Glucagon stimulates _____ from the ____ aka _____
- glucose release
- liver
- Glycogenolysis
11Diabetic KetoAcidosis (DKA) is Diagnosed when blood glucose is >____ mg/dL, presence of _______, urine ketones, blood pH <______ and serum bicarbonate <____ mmol/L
- 200
- serum ketones
- 7.25
- 15
12Criteria for Transitioning to SQ Insulin
Mental status is normal
Able to tolerate sips of clears
HCO3 ≥ 15