Week 8: Circulatory System

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1
Provides communication between widely separated body parts through transportation of hormones, nutrients, wastes, respiratory gases, vitamins, minerals, enzymes, water, leucocytes, and antibodies.
Circulatory System
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transporting medium
Blood
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2 components of blood
a. Plasma
b. Formed elements (RBC)
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Plasma is the   part of the blood
Plasma is the liquid part of the blood
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Plasmis composted of   water, ions, and proteins in the form of   and  
Plasmis composted of 90% water, ions, and proteins in the form of albumins and globulins
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RBC aka  
RBC aka Erythrocytes
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WBC aka  
WBC aka Leucocytes
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Blood Platelets aka  
Blood Platelets aka Thrombocytes
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shape of RBC
Biconcave disk
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RBC is formed in the   (in the sternum, ribs, iliac crest, clavicle, scapulae, and skull)
RBC is formed in the red marrow of vertebrae (in the sternum, ribs, iliac crest, clavicle, scapulae, and skull)
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the principal component of RBC is  
the principal component of RBC is hemoglobin
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Oxygen:  
Carbon Dioxide:  
Oxygen: Iron heme
Carbon Dioxide: Globulin Portion
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Life span of RBC is   days
Life span of RBC is 120 days
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Older, deteriorated RBC are removed by the   cells of the liver, spleen, and bone marrow, and replaced daily
Older, deteriorated RBC are removed by the reticulo-endothelial cells of the liver, spleen, and bone marrow, and replaced daily
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heme in the blood is converted to   (part of the bile)
heme in the blood is converted to bilirubin (part of the bile)
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2 types of Leucocyte or WBC
1. Granulocyte or polymorph nuclear leucocytes
2. Agranulocytes or mononuclear leucocytes
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Originates in the bone marrow and consists of Neutrophil, Basophil, and Eosinophil
Granulocytes or polymorph nuclear leucocytes
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Originates in bone marrow and lymphatic tissue and consists of Monocyte and Lymphocyte
Agranulocytes or mononuclear leucocytes
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3 types of Granulocytes or polymorph
1. Neutrophil
2. Basophil
3. Eosinophil
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2 types of Agranulocytes or mononuclear
1. Monocyte
2. Lymphocyte
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Identify the main target of the Leucocyte:

Bacteria and Fungi
Neutrophil
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Identify the main target of the Leucocyte:

Anti-inflammatory response
Basophil
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Identify the main target of the Leucocyte:

Parasitic infections
Eosinophil
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Identify the main target of the Leucocyte:

destruction of pathogens
Monocyte
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Identify the main target of the Leucocyte:

triggering a specific immune response
Lymphocyte
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Anucleate (no nucleus) cellular fragments associated with hemostasis (blood coagulation)
Thrombocytes or Blood Platelets
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Thrombocytes originate from the fragmentation of   in bone marrow
Thrombocytes originate from the fragmentation of megakaryocytes in bone marrow
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Blood Platelets function in   ( )
Blood Platelets function in blood coagulation (hemostasis)
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Names Indicate type of   present on the  
Names Indicate type of antigen present on the RBC membrane
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The plasma normally contains no   against   present on its own RBC
The plasma normally contains no antibodies against antigens present on its own RBC
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special proteins that fight off and destroy disease-causing germs
Antibodies
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foreign substance introduced into the body and causes immune response; molecules produced by the body.
Antigen
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• Type AB –  
• Type O –  
• Type AB – Universal Recipient
• Type O – Universal Donor
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Heart is a highly muscular pumping organ located in the   enclosed by a  
Heart is a highly muscular pumping organ located in the pericardial cavity enclosed by a pericardium
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Tubes on varying diameters through which blood passes
Blood Vessels
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 Carries oxygenated blood
 Away from the heart
Arteries
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 Carries deoxygenated blood
 Toward the heart
Veins
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 Gas exchange
 joins Arteries and Veins
Capillaries
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Circulation if the blood flow through the  
Circulation if the blood flow through the circuit of vessels
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3 types of circulation
1. Systemic Circulation
2. Pulmonary Circulation
3. Hepatic-portal Circulation
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It is the blood flow from the left ventricle into the aorta, other arteries, arterioles, capillaries, venules and veins to the right atrium of the heart
Systemic Circulation
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It is the blood flow from the right ventricle to the pulmonary artery to lung arterioles, capillaries and venules, and veins, to left atrium of the heart
Pulmonary Circulation
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4 Chambers of the heart
1. Right Atrium ⇑
2. Left Atrium ⇑
3. Right Ventricle ⇓
4. Left Ventricle ⇓
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wall between the chambers of the heart
septum
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- prevents the backflow
- Separates the chamber of the blood
Valve
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largest artery in the human body
Aorta
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powerful contraction from the lower chambers
Ventricular Contraction
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- blood flow from the capillaries, venules, and veins of stomach, intestines, spleen, pancreas, and gall bladder into portal veins, liver sinusoids to hepatic veins, into inferior vena cava, to right atrium of the heart.
Hepatic-portal Circulation
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Hepatic-portal Circulation is the blood flow from the capillaries, venules, and veins of stomach, intestines, spleen, pancreas, and gall bladder into portal veins, liver sinusoids to hepatic veins, into  , to   of the heart.
Hepatic-portal Circulation is the blood flow from the capillaries, venules, and veins of stomach, intestines, spleen, pancreas, and gall bladder into portal veins, liver sinusoids to hepatic veins, into inferior vena cava, to right atrium of the heart.
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Alternate expansion and elastic recoil of blood vessels caused by intermittent ejections of blood from heart into aorta with each ventricular contraction
Pulse
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Pulse can be felt because of   of arterial wall
Pulse can be felt because of elasticity of arterial wall
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Auscultation feeling of Pulse via  
Auscultation feeling of Pulse via stethoscope
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