Population and Evolutionary Genetics

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1
population
group of individuals of the same species hat occupy the same region and can interbreed with each other
2
local populations/demes
make up a large population, are more likely to breed with each other, different locl populations are often seperated by moderate geographic barriers like distance and rivers
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gene pool
all of the alleles of every gene in a population
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who contributes to the gene pool?
only individuals who can reproduce
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What do population geneticists study?
genetic variation within the gene pool and how it changes from one generation to the next
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polymorphism
many traits display variation within a population
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polymorphic
gene that commonly exists as 2 or more alleles in a population
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monomorphic
gene exists predominantly (at least 99%) as a single allele
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single-nucleotide polymorphism (SNP)
base pair variation at specific locations
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allele frequency
(number of copies of an allele in a population)/(total number of all alleles for that gene in a population)
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genotype frequency
(number of individuals with a particular genotype in a population)/(total number of individuals in a population)
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Hardy-Weinberg equation
p^2 + 2pq + q^2 = 1
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GG predominates when...
frequency of g is low
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Gg predominates when...
frequencies of G and g are intermediate
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gg predominates when...
frequency of g is high
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Requirements for Hardy-Weinberg:
no new mutations, no natural selection, large population/no genetic drit, no migration, random mating
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microevolution
changes in gene pool from generation to generation
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4 ways for natural selection on phenotype
directional, balancing, disruptive, stabilizing selection
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directional selection
one extreme phenotype (GG or gg)
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balancing selection
maintenance of two or more alleles
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disruptive selection
survival of two or more different phenotypes
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stabilizing selection
favors the survival of individuals with intermediate phenotypes (Gg)
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What does Darwinian fitness measure?
reproductive superiority, highest reprouctive ability = 1, others are less
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What does natural selection raise?
mean fitness of the population
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balancing selection
heterozygotes have selective advantage (sickel cell)
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disruptive selection
favors two or more phenotypes due to different environments (pepper moth)
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stabilizing selection
extreme phenotypes are selected against, usually for polygenic traits like weight and number of eggs
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What size population has greater genetic drift?
small
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genetic drift
random changes in allele frequencies that are not under selection pressure
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bottleneck effect
dramatic reduction in population size
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founder effect
small group of individuals seperate from a larger population and establishes a colony in a new location
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gene flow
transfer of alleles from donor to recipient population, changing its gene pool
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conglomerate
recipient population of gene flow
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inbreeding
mating between genetically related individuals
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outbreeding
mating between genetically unrelated individuals
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assortative mating
individuals do not mate randomly
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positive assortative mating
individuals are mroe likely to mate because phenotypically similar
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negative assortative mating
individuals more likely to mate because phenotypically different
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species
group of individuals that can produce viable, fertile offspring
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speciation
generation of reproductive isolation
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What are the two types of speciation?
anagenesis and cladogenesis
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anagenesis
single species is transformed into a different one over the course of many generations
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cladogenesis
single species is divided into two or more species, most common form of speciation
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What are the types of cladogenesis?
allopatric, parapatric, sympatric
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