1Gail risk that qualifies women over 35 for preventative breast cancer treatment
1.7% over 5 years
2tamoxifen hot flashes treatment
venlafaxine
clonidine
paroxetine not used due to drug interactions
3Aromatase inhibitors we should know
anastrozole
letrozole
exemestane
4What is fulvestrant?
SERD, downregulator or estrogen receptor
5How do CDK 4/6 inhibitors work?
Inhibit transition of cell from G0/G1 phase to S phase
6CDK 4/6 inhibitors we should know
Palbociclib -neutropenia
Ribociclib -neutropenia
Abemaciclib -diarrhea
7HER2 we should know
Trastuzumab
Peruzumab
Ado-trastuzumab emtansine
Neratinib
8Dose-dense AC + T
Doxorubicin, cyclophosphamide, and paclitaxel
9TC
docetaxel, cyclophosphamide
10Docetaxel pre drugs
8mg dexamethasone BID 3 days before treatment
11paclitaxel pre drugs
dexamethasone, diphenhydramine, H2- antagonist 30 minutes before