Breast Cancer

Question 1

Gail risk that qualifies women over 35 for preventative breast cancer treatment

Accepted Answer

1.7% over 5 years

Question 2

tamoxifen hot flashes treatment

Accepted Answer

venlafaxine clonidine paroxetine not used due to drug interactions

Question 3

Aromatase inhibitors we should know

Accepted Answer

anastrozole letrozole exemestane

Question 4

What is fulvestrant?

Accepted Answer

SERD, downregulator or estrogen receptor

Question 5

How do CDK 4/6 inhibitors work?

Accepted Answer

Inhibit transition of cell from G0/G1 phase to S phase

Question 6

CDK 4/6 inhibitors we should know

Accepted Answer

Palbociclib -neutropenia Ribociclib -neutropenia Abemaciclib -diarrhea

Question 7

HER2 we should know

Accepted Answer

Trastuzumab Peruzumab Ado-trastuzumab emtansine Neratinib

Question 8

Dose-dense AC + T

Accepted Answer

Doxorubicin, cyclophosphamide, and paclitaxel

Question 9

TC

Accepted Answer

docetaxel, cyclophosphamide

Question 10

Docetaxel pre drugs

Accepted Answer

8mg dexamethasone BID 3 days before treatment

Question 11

paclitaxel pre drugs

Accepted Answer

dexamethasone, diphenhydramine, H2- antagonist 30 minutes before

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