Circulatory System

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1
What is the circulatory sytem
The circulatory system includes all of your vasculature (blood vessels) and the heart! It's where the heart contracts to pump blood around the body in a double loop system.
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blue
deoxygenated
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red
oxygenated
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what is the difference between pulmonary loop and systemic loop of our circulatory system
The pulmonary loop brings blood to the lungs so that RBCs can complete gas exchange with alveoli. The systemic loop carries blood to the body tissues and then back to the heart.
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what is the advantage of a double-loop circulatory system
This allows for the separation of oxygenated and deoxygenated blood and ensures that body tissues have a constant supply of oxygen for cellular respiration
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diastole
when the atria and ventricles (cardiac muscle) is at rest.
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systole
when the atria and ventricles contract.
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when does atrial systole
atrial systole occurs directly before ventricular systole.
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when the heart is at rest, which valves are open allowing blood to fill both atria and ventricles
atrioventicular valves (av valves)
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av valves
atrioventicular valves
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why would atrial contraction before ventricle contraction be an efficient way of pushing the max amount of blood out of the heart when the ventricles contract?
Maximizes the amount of blood in the ventricles during contraction (allows atria to empty into ventricles)
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as the atria contract, would the pressure inside of the atria increase or decrease? why?
increase (because volume in the atria decreases)
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as the ventricles start to contract, the av valves close -- why is this important
it prevents backflow of blood (ensures that all blood is pumped from the ventricles to the pulmonary or systemic loops)
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when the ventricles contract, would the pressure inside of he ventricles increase or decrease? why?
Increase (because the volume inside of the ventricles decreases)
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as pressure builds in the ventricles, they push open the sl valves. where will the blood go when the sl valves open?
To the pulmonary or systemic loops of the circulatory system (depending on right or left ventricle)
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the sl valves close when the ventricles relax (are in diastole) --why is this important?
to prevent backflow of blood
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whats the first heartbeat sound
the blood hitting the clsoed av valves makes the 1st heartbeat sound
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whats the second heartbeat sound
the blood hitting the closed sl valves makes the 2nd heartbeat sound
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how is pressure changes in the heart
contraction of the chambers. These pressure changes control the opening and closing of AV and SL valves in the heart.
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this is when the av valves close because the pressure in the ventricles is higher/lower than the atria.
higher
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What is the circulatory sytem
The circulatory system includes all of your vasculature (blood vessels) and the heart! It's where the heart contracts to pump blood around the body in a double loop system.
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ventricular pressure exceeds that of the arteries. this causes the SL/AV valves to open. blood will start to enter which arteries?
sl ; the pulmonary artery and aorta
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when a chamber of the heart contracts
volume decrease so pressure increase
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what happens during 0.0-0.1 during the cardiac cycle
+ the atria contract causing a rapid but relatively small pressure increase, which pumps blood from the atria to the ventricles, through the open atrioventricular valves
+ teh semilunar valves are closed and blood pressure in the arties gradually drops to it minimum as blood contrinues to flow along them but no more is pumped in.
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0.1-0.15 of cardiac cycle
the centricles contract with a rapid pressure build up that causes the atrioventricular valves to close

the semilunar valves remain closed
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0.15-0.4 of cardiac cycle
the pressure in the ventricles rises above the pressure in the artieries so the semilunar valves open and blood is pumped from the ventricles into the arteries, translently maximazing the arterial blood presure

pressure slowly rises in the atria as blood drains into them from the veins and they fill
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0.4-0.45 of cardiac cycle
the contraction of the ventricular muscles wanes and pressure inside the ventricles rapidly drops below the pressure in the artieries ,causing the semilunar valves to close

the atrioventricular valves remain closed
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0.45-0.8 of cardiac cycle
pressure in the ventricles drops below the pressure in the atria so the atrioventricular valves opens

blood from the veins drains into the atria and from there into the ventricles, causing a slow increase in pressure
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as the ventricles relax, the sl valves close at 0.4, this is because of the pressure of the ventricles is higher/lower than the arteries
lower
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explain why it is essecntial that the sl valves close when the ventricles begin to relax
So that blood can be pumped through the pulmonary artery to the lungs and through the aorta to the body tissues and backflow will not occur
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why does the arterial pressure begin to drop after 0.4 seconds
after the intial pump of blood into the artieries, pressure begins to decrease as it desperses
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explain why the pressure in the atria begins to drop after 0.45 seconds
AV valves begin opening as the pressure in the ventricles drops below the pressure in the atria (which have been gradually filling with blood from the vena cava and pulmonary veins)
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sinoatrial node (SA Node)
The heartbeat is actually controlled by a specialized group of cells in the right atrium called the sinoatrial (SA) node.
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myogenic contraction
contraction that is controlled by muscle cells directly
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sa node is sometimes called
the pacemaker
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pacemaker
sets the pace for the beating of the heart
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which chamber of the heart is the sa node lovated
right atrium
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how do electrical signal spread in the heart
1) sa node gernates impulse; atrial excilation begins
2) impulse delayed at av node
3) impulse passes to heart apex; ventricular excitation begins (goes through bundle branches)
4) ventricular excitation complete (goes thorugh purkinje fibers)
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signals from the sinatrial node that causes contaction cannot pass directly from atria to ventricles. instead the signal reaches another cluster of cells called
av node
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where is the av node
middle of the four chambers
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purkinje fibers
ventricular contraction (systole) will occur once the electrical impulse has spread down the septum towards the apex of the heart and around the ventricles by nerve fibers called purkinje fibers
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do the ventricles contract simultaneously like the atria do
yes
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how are the cardiac muscles shaped
y shaped
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why are cardiac muscle cells shaped a certain way
Cardiac muscle cells are branched (Y-shaped) to connect to multiple fibers. They are connected by intercalated discs, where cytoplasm between the cells is connected for faster transmission of electrical impulses that control contraction.
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intercalated disc
special regions where the cytoplasm of one cells connects with the next for rapid transmission of the contraction signal
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cardiac muscle fibers als ohave a lot of mitochondria and plenty of stored glycogen. which cellular process would these component helps with?
Energy! The mitochondria undergo cellular respiration to ensure energy supply for cardiac muscle contraction. Cellular respiration requires glucose, and glycogen is a polysaccharide of glucose molecules. If glucose concentration gets too low, glycogen can be broken down to ensure that cellular respiration can continue.
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electrocardiogram name simplified
EKG
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what is EKG
records the electrical signals from the heart through a series of electrodes.
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what is p wave
atrial systole (contaction) due to sa node trigger
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pr interval
delay of av node allowing filling of ventricles
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QRS complex
ventricular systole (contraction) due to purkije fibers
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st segment
veginning of venetricular relaxation
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t wave
ventricular diastole (relax
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explain why the qrs wave has a larger amplitude than the p wave
Ventricular contraction (QRS complex) requires more of an impulse to occur than atrial contraction (P-wave)
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defibrillation
delviers a electrical shock to the sa node to reeestablish normal rhythm; used when there is a disruption in the heart's electrical activity such as ventricular fibrillation
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ventricular fibrillation
fast and irreglar heartbet
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aed stands for
Automated External Defibrillator
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what is aed
it can be used in first aid emergencies involving heart activity.
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pacemaker
monitor electrical cardiac activity.
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suggest why the electrical impulses from an artifical pacemaker are delivered to the right side of the heart
The right side of the heart naturally controls heart rate, so contraction of these cardiac muscle fibers will influence the left side to contract at the same time.
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heart is connected to what part of brain
medulla
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lowering pH increases...
breathing rate and heart rate h
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what happens when heart race increases
increase the amount of gas exchange occurring between alveoli and capillaries.
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why would hormone epinephrine be released
response to stress
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if the medulla detects high Co2 levels, will this cause an increase or decrease in heart beats? how do ou know?
An increase in heart beats -- pump more blood to complete more gas exchange in the lungs
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if the medulla detects high blood pressure, will this cause an increase ro decrease in the heart beats? how do you know ?
decreases heart beats to decrease rpessure on arterial walls
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how does the hormone epinphrine change your heart rate?
release of epinephrine increases your heart rate
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types of blood vessels
arteries, veins, and capilaries
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how are blood vessels distinct
The distinctions between these vessels have to do with the direction in which they carry blood.
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what kind of cell wall does artieries have
thickest wall to withstand high blood pressures.
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veins
eins have wider lumens and valves to prevent backflow as they return blood to the heart.
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capilaries
Capillaries are thin and branched and have fenestrations (windows) to allow for efficient gas exchange with tissues.
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is the pathwar of blood for artieries away or towards the heart
away
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is the pathwar of blood for veins away or towards the heart
toward
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lumen width arteries
narrow
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lumen width veins
wide
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pressure of blood of arteries
high
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pressure of blood of veins
lowest
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pressure of blood of capilaries
low
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wall thickness of artieries
thick
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wall thickness of veins
thin
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wall thickness of capillaries
thinnest
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function of artieries
built for withstanding and maintaining high pressure; elasticity = ppulsing action
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function veins
built to max blood flow in one direction, at low pressure, against gravity
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function vapilatries
built for exchange of materials
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when veins and artieries are contricted, that meeans
lumen diameter decreases
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when veins and artieries are dilated, that meeans
lumen diameter increases
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why is contriction and dilation of veins and artieries important
the body is able to controls blood pressure and the amount of gas or nutrient exchange occurring in tissues by changing the rate at which blood travels around the body.
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what is the advantage of dilation of blood vessels when we are hot
More blood can near the surface of the skin to dissipate body heat
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why do capilaries have pores between capilary cells
makes it easier to echange materials
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how tick are walls of capillaries . why?
one cell layer thick, helps gas exhcnage occur more eddiviently
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blood pressure waht is it
When the ventricles contract and blood is pumped through the arteries, the blood exerts a pressure on the artery walls.
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chronic high blood pressure
high blood pressure for an extended duration of time).
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sphygmomanometer
measures two values -- the blood pressure during ventricular systole (contraction) and ventricular diastole (relaxation).
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range of healthy blood pressure
<120 (systolic) and <80 (diastolic)
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systolic pressure
pressure in the artieries when ventricles contract
normal == 120 mmHg
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diastolic pressure
pressure in the arteries when ventricles relax
normal = 80 mmHg
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why the pressure in arteries during ventricular contraction is higher than when the ventricles relax
During ventricular contraction a higher volume of blood is pumped into the arteries. When ventricles relax this volume of blood dissipates through the body and pressure decreases.
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what features of the artieries maintian the pressure of the blood even when the heart is relaxed?
Smooth muscle and stretchy, elastic fibers (mostly the protein elastin) in the tunica media
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why is salt a risk factor for hypertension
More salt (solute) in the blood will result in more retention of water in the blood, thus increasing the blood volume
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what causes high blood pressure (hypertension)
salt, obestiy
smoking
genetics
cholestrol
anger
stresss
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atherosclerosis
When cholesterol, other lipids, or other cellular debris accumulate in an artery, they form a plaque. This restricts blood flow, and if it bursts it can form a blood clot.
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how to treat atheroclerosis
Changes to diet and medication can help treat atherosclerosis.
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coronary heart disease (CHD)
a catch-all term for any disease or disorder that influences the structure and therefore function of the heart and its vasculature.
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what is the most common type of CHD
coronary artery disease
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what happens with coronary artery disease
where atherosclerosis occurs in the coronary artery and restricts blood flow to heart tissue.
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what causes myocardial infarction
If the blockage in the coronary artery becomes complete or severely restricts blood flow to cardiac muscle, tissue death can result.
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another word for heart attack
myocardial infarction
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plaque
buildup of cholesterol
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what can increaseases chances of blockage of cornary arteries
high ldl
chronic high blood glucose
hypertension
trans-unsaturated fats
strees
smoking
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occlusion
blockage
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consequences result from occlusion of coronary artereis
angina
myocardial infarction
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angina
heart pain
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