Neuro Exam V

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1
parts of the outer ear
pinna, auditory canal, tympanic membrane
2
function of outer ear
direct sound pressure changes to the tympanic membrane
3
structure of the middle ear
3 bones and 2 muscles in an air-filled cavity with a pressure equalizing (eustachian) tube
4
function of the middle ear
impedence matching and attenuation reflex
5
parts of inner ear
vestibular system and cochlea
6
function of inner ear
transduction, tonotopic organization, balance
7
transduction of sound
stapes movement on the oval window displaces perilymph in scala vestibuli + endolymph in scala media, which deflects basilar membrane and moves hair cells on organ of Corti, which bends stereocilia, which opens mechano-gated K+ channels causing depolarization, which triggers exocytosis and releases glutamate that binds to the neurites of the auditory nerve.
8
function of outer hair cells
cochlear amplifier, increase amplitude of traveling wave due to embedded motor proteins which cause them to shorten during depolarization
9
auditory pathway
hair cells, spiral ganglion, ipsilateral cochlear nuclei, ipsilateral and contralateral superior olive, inferior colliculus, thalamus, auditory cortex
10
frequency detection at 200Hz and below
phase locking
11
frequency detection between 200 and 4kHz
phase locking (volley principle), tonotopy
12
frequency detection at 4kHz and above
tonotopy alone
13
sound location for low frequencies
interaural time delay (discrete sound), phase delay (continuous sound)
14
sound location for high frequencies
interaural intensity difference/head shadow effect
15
intensity encoding
amount of basilar membrane deflection, amplitude of traveling wave
16
structure of otoliths
both have a macula, with cilia on hair cells projecting into a gelatinous cap with calcium carbonate crystals on top
17
structure of semicircular canals
hair cells cluster in a bulge of the fluid filled tube (ampulla), and cilia project into a gelatinous area (cupula)
18
transduction of head tilt (linear motion)
gravity/motion pulls on otoliths, deforming gelatinous cap, bending cilia, resulting in depolarization
19
transduction of rotational movement
fluid in semicircular canals moves on a delay relative to walls of the canal, exerting force on the cupula and bending the cilia
20
vestibular pathway
vestibular cells, scarpa's ganglion, ipsilateral medial + lateral vestibular nuclei. MVN, medial longitudinal fasciculus, neck and eye muscles. LVN, vestibulospinal tract, cerebellum, limb motor neurons
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