1What are tissues?
Collections of specialized cells and cell products that perform a limited number of functions.
2What is the study of tissues?
histology
3The four tissue types are
epithelial, connective, muscular, nervous
4What is epithelial tissue?
linking, covering, secreting, absorbing
5What is connective tissue?
connects tissues physically or chemically
6What is muscular tissue?
causes motion, generates heat
7What is nervous tissue?
connect tissues electrically
8What is a zygote?
fertilized egg
9What is a blastula?
an animal embryo at the early stage of development when it is a hollow ball of cells.
10What is gastrulation?
Invagination of blastocyst to form gastrula.
Formation of three cell layer.
11What are protostomes?
Animals that develop the mouth before the anus
12What are deuterostomes?
Animals that develop the anus before the mouth
13What are primary germ layers?
endoderm, mesoderm, ectoderm
14What is the endoderm?
the innermost germ layer and lines the developing digestive tube and other internal organs
15What is the mesoderm?
middle germ layer, forms muscle, the skeletal system, kidneys and the circulatory system
16What is the ectoderm?
most exterior germ layer, forms skin, brain, the nervous system, and other tissues.
17Characteristics of epithelial tissues.
cells/tissues that secrete things, a-vascular, cell junctions, polarity, regeneration
18What is apical side?
part of the epithelia that touches open spaces
19What is basolateral side?
part that touches the connective tissue
20What is the base lamina?
separates cells from underlying connective tissues
21What is the function of epithelial tissue?
To cover and line the surfaces of organs and body openings. First layer of protection.
22Function of epithelial tissue?
protection, absorption, filtration, excretion, secretion, sensory reception
23physical protection of epithelial tissue
Protects from dehydration, abrasion, destruction
24control permeability of epithelial tissue
Some protective barriers, some contain "machinery" for absorption, secretion
25Epithelial tissues provide sensation.......
touch, vision, taste, smell
26Specializations of epithelial cells
1. Move fluids over the epithelium (protection)
2. Move fluids through the epithelium (permeability)
3. Produce secretions (protection and messengers)
27polarity of epithelial tissue
has an apical surface and a basal surface
28What do microvilli do?
increase surface area for absorption
29What do cilia do?
moves stuff along the cell's surface
30What are tight junctions?
Membranes of neighboring cells are pressed together, preventing leakage of extracellular fluid
31What are gap junctions?
Small tunnels that connect cells, facilitating the movement of small molecules and ions between the cells.
32Epithelia are classified based on two characteristics:
1. Number of cell layers in the tissue
2. Shape of apical surface cells
33Three types of epithelial tissues based on cell layers:
1. Simple = a single layer
2. Pseudostratified = a single layer so dense that the nuclei give the appearance of multiple cell layers
3. Stratified = two or more layers
34Three types of epithelial tissues based on shape:
1. Squamous = flat
2. Cuboidal = 3D square
3. Columnar = 3D rectangle
35What are the eight different epithelia?
1. Simple Squamous
2. Simple Cuboidal (some ciliated)
3. Simple columnar (some ciliated)
4. Stratified Squamous (in skin, it is keratinized)
5. Stratified Cuboidal
6. Stratified Columnar
7. Transitional
8. Pseudostratified
36What is the glue that hold many tissues together?
connective tissues
37Mesenchyme is:
an embryonic connective tissue
38What is the matrix of connective tissue?
ground substance and fibers made from proteins
39What is ground substance?
unstructured material that fills the space between the cells and contains the fibers. Can be liquid, semi-solid, gel-like or very hard
40What are the fibers of connective tissue?
collagen, elastic, reticular
41What are collagen fibers?
Most common fibers in connective tissue proper
Long, straight, and unbranched
Strong and flexible
Resist force in one direction
For example, tendons and ligaments
42What are elastic fibers?
Contain elastin, branched and wavy, return to original length after stretching
43What are reticular fibers?
Network of interwoven fibers, strong and flexible, resist force in many directions, stabilize functional cells
44What are the cells of connective tissues?
1. fibroblasts
2. chondroblasts
3. osteoblasts
4. hematopoietic stem cells
5. adipocytes
45What are fibroblasts?
cells that secrete fibrous proteins like elastin and collagen
46What are chondroblasts?
cartilage forming cells
47What are osteoblasts?
bone forming cells
48What are hematopoietic stem cells?
found in red bone marrow and forms blood cells
49What are adipocytes?
fat cells
50What are mesenchymal cells?
stem cells that respond to injury or infection
51What are macrophages?
They are big eaters that engulf debris, foreign materials, bacteria, and viruses.
52What are mast cells?
Stimulate inflammation after injury or infection. Release histamine and heparin.
53What are lymphocytes?
specialized innumerable cells in lymphatic system.
54Four main types of adult connective tissue.
1. connective tissue proper(loose CT & dense CT)
2. cartilages
3. bone
4. fluid connective tissue
55Classification of connective tissue proper.
1. loose - areolar, reticular, adipose
2. dense - dense regular, dense irregular, elastic
56Classification of cartilages:
1. hyaline
2. elastic
3. fibrocartilage
57Classification of fluid connective tissue:
1. blood
2. lymph
58What is the lamina proprietor?
found under many mucous membranes and right under epithelium of skin - hold blood vessels and capillary beds (areolar CT - loose)
59Two types of adipose tissue
1. white fat
2. brown fat
60What is white fat?
Most common
Stores fat
Absorbs shocks
Slows heat loss (insulation)
61What is brown fat?
1. more vascularized tissue
2. fat breakdown accelerates when stimulated by nervous system, releasing energy
3. absorbs energy from surrounding tissues
62What is reticular connective tissue?
1. loose ground substance with many reticular fiber networks
2. forms soft internal skeleton that supports other cell types
3. forms a structural framework for organ cells in many organs/tissues
4. found in lymph nodes, bone marrow and the spleen
63What is dense regular connective tissue?
1. primarily parallel collagen fibers
2. a few elastic fibers
3. major cell type is the fibroblast
4. attaches muscles to bone and bone to bone
5. found in tendons and ligaments
6. poorly vascularized
64What is dense irregular CT?
1. collagen fibers with some elastic fibers
2. major cell type is fibroblasts
3. withstands tension in many directions
4. major tissue found in the dermis of skin, digestive tract and fibrous oran capsules
65What are supporting connective tissues?
cartilage and bone
66Three types of cartilage
hyaline, elastic, fibrocartilage
67What is hyaline cartilage?
1. most common and hardest
2. amorphous, firm matrix with a network of collagen fibers
3. chondroblast and chondrocytes lie in lacunae
4. supports, reinforces, cushions, and resists compression
5. found in embryonic skeleton, end of long bones, nose, trachea, larynx, connects ribs to sternum
68What is elastic cartilage?
1. similar to hyaline but with more elastic fibers
2. lacunae are much closer together with visible elastic fibers
3. flexible
4. maintains shape and structure while allowing flexibility
5. not very common-supposts external ear and epiglottis
69What is fibrocartilage?
1. blend of hyaline and elastic
2. matrix less firm with thick collagen fibers
3. provides tensile strength and absorbs compression shock
4. smaller lacunae, farther apart in small groupings
5. found in inter-vertebral discs, the pubic symphysis and discs of the knee joint
70What is bone connective tissue?
1. hard, calcified matrix with collagen fibers
2. osteocytes are found in lacunae and bone is well vascularized
3. Other bone cells are osteoclasts (bone breakers) and osteoblasts (bone makers)
4. supports, protects and provides levers for muscular action
5. stores calcium, minerals and fat
6. red bone marrow inside bones
7. compact bone is found in the shafts of most bones
8. spongy bone is typical for flat bones and ends of long bones
71What is fluid connective tissue?
1. blood contained within the heart or blood vessels
2. Mature red blood cells have no nucleus
3. functions in transport of respiratory gases, defense and immune response and blood clotting
72Blood contains what?
red blood cells, white blood cells, platelets
73What are erythrocytes?
red blood cells
74What are leukocytes?
white blood cells
75What are thrombocytes?
platelets
76What is pseudo stratified epithelium?
1. single layer of cells with different heights
2. nuclei are seen at different layers
3. function in secretion and propulsion of mucus
located in the trachea (ciliated) and sperm-carrying ducts (non-ciliated)
77What is stratified squamous epithelium?
1. thickest epithelia composed of many layers (more than 5)
2. function - protection(skin epidermis and every entrance and exit point into the body)
3. if inside body - non-keratinized
4. if outside body - keratinized
78Two types of glands in the body.
exocrine and endocrine
79What is an endocrine gland?
1. release hormones into bloodstream
2. duct-less
3. not all are epithelial derivatives
80What is an exocrine gland?
1. almost all are derived from epithelial tissues
2. named according to function(saliva gland, sebaceous gland)
3. secrete through ducts onto the surface of the gland
81What is stratified cuboidal?
1. found in ducts of exocrine glands(sweat and mammary)
2. two -three cell layers
82What is stratified columnar?
1. limited distribution. 2-3 layers thick
2. found in pharynx, male urethra, and linking some glandular ducts
83What is transitional epithelium?
1. not more than 3 layers of cells
2. surface cells are cuboidal to dome shaped
3. stretches to permit the dissension of the bladder
4. only found in urinary system
84Where is nervous tissue found?
brain, spinal cord, nerves
85What are the two kinds of cell types of the nervous system?
1. neurons
2. neuroglia cells
86What are the 3 main parts of nervous tissue?
1. cell body with nucleus (soma)
2. dendrites: small extension that receive signals from other neurons
3. axon: longer extension via which the electrical signal propagates
87What are the 3 types of muscle tissue?
skeletal, cardiac, smooth
88What is skeletal muscle?
1. striated (showing vertical lines)
2. cells are long and run parallel along the muscle
3. cell are multi-nucleated (many nuclei per cell)
4. voluntary muscle cells
89What is cardiac muscle?
1. striated (vertical lines)
2. cells are microscopic short, rectangular, connect one to another via intercalated disc
3. disc have gap junction and allow cell to cell communication
4. one nucleus per cell
5. in-voluntary
90What is smooth muscle?
1. no striations
2. cells are microscopic short, spindle-like, one nucleus per cell
3. in-voluntary