Chapter 6 LAB - Tissues

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1
What are tissues?
Collections of specialized cells and cell products that perform a limited number of functions.
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What is the study of tissues?
histology
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The four tissue types are
epithelial, connective, muscular, nervous
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What is epithelial tissue?
linking, covering, secreting, absorbing
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What is connective tissue?
connects tissues physically or chemically
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What is muscular tissue?
causes motion, generates heat
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What is nervous tissue?
connect tissues electrically
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What is a zygote?
fertilized egg
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What is a blastula?
an animal embryo at the early stage of development when it is a hollow ball of cells.
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What is gastrulation?
Invagination of blastocyst to form gastrula.
Formation of three cell layer.
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What are protostomes?
Animals that develop the mouth before the anus
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What are deuterostomes?
Animals that develop the anus before the mouth
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What are primary germ layers?
endoderm, mesoderm, ectoderm
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What is the endoderm?
the innermost germ layer and lines the developing digestive tube and other internal organs
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What is the mesoderm?
middle germ layer, forms muscle, the skeletal system, kidneys and the circulatory system
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What is the ectoderm?
most exterior germ layer, forms skin, brain, the nervous system, and other tissues.
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Characteristics of epithelial tissues.
cells/tissues that secrete things, a-vascular, cell junctions, polarity, regeneration
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What is apical side?
part of the epithelia that touches open spaces
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What is basolateral side?
part that touches the connective tissue
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What is the base lamina?
separates cells from underlying connective tissues
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What is the function of epithelial tissue?
To cover and line the surfaces of organs and body openings. First layer of protection.
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Function of epithelial tissue?
protection, absorption, filtration, excretion, secretion, sensory reception
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physical protection of epithelial tissue
Protects from dehydration, abrasion, destruction
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control permeability of epithelial tissue
Some protective barriers, some contain "machinery" for absorption, secretion
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Epithelial tissues provide sensation.......
touch, vision, taste, smell
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Specializations of epithelial cells
1. Move fluids over the epithelium (protection)
2. Move fluids through the epithelium (permeability)
3. Produce secretions (protection and messengers)
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polarity of epithelial tissue
has an apical surface and a basal surface
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What do microvilli do?
increase surface area for absorption
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What do cilia do?
moves stuff along the cell's surface
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What are tight junctions?
Membranes of neighboring cells are pressed together, preventing leakage of extracellular fluid
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What are gap junctions?
Small tunnels that connect cells, facilitating the movement of small molecules and ions between the cells.
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Epithelia are classified based on two characteristics:
1. Number of cell layers in the tissue
2. Shape of apical surface cells
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Three types of epithelial tissues based on cell layers:
1. Simple = a single layer
2. Pseudostratified = a single layer so dense that the nuclei give the appearance of multiple cell layers
3. Stratified = two or more layers
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Three types of epithelial tissues based on shape:
1. Squamous = flat
2. Cuboidal = 3D square
3. Columnar = 3D rectangle
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What are the eight different epithelia?
1. Simple Squamous
2. Simple Cuboidal (some ciliated)
3. Simple columnar (some ciliated)
4. Stratified Squamous (in skin, it is keratinized)
5. Stratified Cuboidal
6. Stratified Columnar
7. Transitional
8. Pseudostratified
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What is the glue that hold many tissues together?
connective tissues
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Mesenchyme is:
an embryonic connective tissue
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What is the matrix of connective tissue?
ground substance and fibers made from proteins
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What is ground substance?
unstructured material that fills the space between the cells and contains the fibers. Can be liquid, semi-solid, gel-like or very hard
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What are the fibers of connective tissue?
collagen, elastic, reticular
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What are collagen fibers?
Most common fibers in connective tissue proper
Long, straight, and unbranched
Strong and flexible
Resist force in one direction
For example, tendons and ligaments
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What are elastic fibers?
Contain elastin, branched and wavy, return to original length after stretching
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What are reticular fibers?
Network of interwoven fibers, strong and flexible, resist force in many directions, stabilize functional cells
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What are the cells of connective tissues?
1. fibroblasts
2. chondroblasts
3. osteoblasts
4. hematopoietic stem cells
5. adipocytes
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What are fibroblasts?
cells that secrete fibrous proteins like elastin and collagen
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What are chondroblasts?
cartilage forming cells
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What are osteoblasts?
bone forming cells
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What are hematopoietic stem cells?
found in red bone marrow and forms blood cells
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What are adipocytes?
fat cells
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What are mesenchymal cells?
stem cells that respond to injury or infection
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What are macrophages?
They are big eaters that engulf debris, foreign materials, bacteria, and viruses.
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What are mast cells?
Stimulate inflammation after injury or infection. Release histamine and heparin.
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What are lymphocytes?
specialized innumerable cells in lymphatic system.
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Four main types of adult connective tissue.
1. connective tissue proper(loose CT & dense CT)
2. cartilages
3. bone
4. fluid connective tissue
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Classification of connective tissue proper.
1. loose - areolar, reticular, adipose
2. dense - dense regular, dense irregular, elastic
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Classification of cartilages:
1. hyaline
2. elastic
3. fibrocartilage
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Classification of fluid connective tissue:
1. blood
2. lymph
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What is the lamina proprietor?
found under many mucous membranes and right under epithelium of skin - hold blood vessels and capillary beds (areolar CT - loose)
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Two types of adipose tissue
1. white fat
2. brown fat
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What is white fat?
Most common
Stores fat
Absorbs shocks
Slows heat loss (insulation)
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What is brown fat?
1. more vascularized tissue
2. fat breakdown accelerates when stimulated by nervous system, releasing energy
3. absorbs energy from surrounding tissues
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What is reticular connective tissue?
1. loose ground substance with many reticular fiber networks
2. forms soft internal skeleton that supports other cell types
3. forms a structural framework for organ cells in many organs/tissues
4. found in lymph nodes, bone marrow and the spleen
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What is dense regular connective tissue?
1. primarily parallel collagen fibers
2. a few elastic fibers
3. major cell type is the fibroblast
4. attaches muscles to bone and bone to bone
5. found in tendons and ligaments
6. poorly vascularized
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What is dense irregular CT?
1. collagen fibers with some elastic fibers
2. major cell type is fibroblasts
3. withstands tension in many directions
4. major tissue found in the dermis of skin, digestive tract and fibrous oran capsules
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What are supporting connective tissues?
cartilage and bone
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Three types of cartilage
hyaline, elastic, fibrocartilage
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What is hyaline cartilage?
1. most common and hardest
2. amorphous, firm matrix with a network of collagen fibers
3. chondroblast and chondrocytes lie in lacunae
4. supports, reinforces, cushions, and resists compression
5. found in embryonic skeleton, end of long bones, nose, trachea, larynx, connects ribs to sternum
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What is elastic cartilage?
1. similar to hyaline but with more elastic fibers
2. lacunae are much closer together with visible elastic fibers
3. flexible
4. maintains shape and structure while allowing flexibility
5. not very common-supposts external ear and epiglottis
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What is fibrocartilage?
1. blend of hyaline and elastic
2. matrix less firm with thick collagen fibers
3. provides tensile strength and absorbs compression shock
4. smaller lacunae, farther apart in small groupings
5. found in inter-vertebral discs, the pubic symphysis and discs of the knee joint
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What is bone connective tissue?
1. hard, calcified matrix with collagen fibers
2. osteocytes are found in lacunae and bone is well vascularized
3. Other bone cells are osteoclasts (bone breakers) and osteoblasts (bone makers)
4. supports, protects and provides levers for muscular action
5. stores calcium, minerals and fat
6. red bone marrow inside bones
7. compact bone is found in the shafts of most bones
8. spongy bone is typical for flat bones and ends of long bones
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What is fluid connective tissue?
1. blood contained within the heart or blood vessels
2. Mature red blood cells have no nucleus
3. functions in transport of respiratory gases, defense and immune response and blood clotting
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Blood contains what?
red blood cells, white blood cells, platelets
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What are erythrocytes?
red blood cells
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What are leukocytes?
white blood cells
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What are thrombocytes?
platelets
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What is pseudo stratified epithelium?
1. single layer of cells with different heights
2. nuclei are seen at different layers
3. function in secretion and propulsion of mucus
located in the trachea (ciliated) and sperm-carrying ducts (non-ciliated)
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What is stratified squamous epithelium?
1. thickest epithelia composed of many layers (more than 5)
2. function - protection(skin epidermis and every entrance and exit point into the body)
3. if inside body - non-keratinized
4. if outside body - keratinized
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Two types of glands in the body.
exocrine and endocrine
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What is an endocrine gland?
1. release hormones into bloodstream
2. duct-less
3. not all are epithelial derivatives
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What is an exocrine gland?
1. almost all are derived from epithelial tissues
2. named according to function(saliva gland, sebaceous gland)
3. secrete through ducts onto the surface of the gland
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What is stratified cuboidal?
1. found in ducts of exocrine glands(sweat and mammary)
2. two -three cell layers
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What is stratified columnar?
1. limited distribution. 2-3 layers thick
2. found in pharynx, male urethra, and linking some glandular ducts
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What is transitional epithelium?
1. not more than 3 layers of cells
2. surface cells are cuboidal to dome shaped
3. stretches to permit the dissension of the bladder
4. only found in urinary system
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Where is nervous tissue found?
brain, spinal cord, nerves
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What are the two kinds of cell types of the nervous system?
1. neurons
2. neuroglia cells
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What are the 3 main parts of nervous tissue?
1. cell body with nucleus (soma)
2. dendrites: small extension that receive signals from other neurons
3. axon: longer extension via which the electrical signal propagates
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What are the 3 types of muscle tissue?
skeletal, cardiac, smooth
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What is skeletal muscle?
1. striated (showing vertical lines)
2. cells are long and run parallel along the muscle
3. cell are multi-nucleated (many nuclei per cell)
4. voluntary muscle cells
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What is cardiac muscle?
1. striated (vertical lines)
2. cells are microscopic short, rectangular, connect one to another via intercalated disc
3. disc have gap junction and allow cell to cell communication
4. one nucleus per cell
5. in-voluntary
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What is smooth muscle?
1. no striations
2. cells are microscopic short, spindle-like, one nucleus per cell
3. in-voluntary
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