1excitatory neurotransmitter produced at the raphe nuclei of the brainstem, decreased during NREM sleep, and almost absent during REM
sleep
- melatonin
- glutamate
- serotonin
- dopamine
2It is an excitatatory neurotransmitter produced in the substantia nigra, ventral tegmental area and hypothalamus of the brain
- dopamine
- glutamate
- norepinephrine
3This inhibitory neurotransmitter is produced in the pineal gland, is located below the corpus callusom and part of the endocrine system.
4The neurons that produce these neurotransmitters are located in the perifornical area of the dorsolateral hypothalamus and project to all the areas of the CNS and
spinal cord. Activation of these neurons during wakefulness is produced by
intrinsic depolarization and by glutamatergic activation
- Hypocretin(Orexin)
- Glutamate
- GABA
- Nitric Oxide
5is an excitatory neurotransmitter important in cognitive function.
Levels of this neurotransmitter in the hypothalamus and cortex are elevated during wakefulness and during REM sleep.
- Glutamate
- Aspertate
- Acetylcholine
6These are the neurotransmitters that binds to both muscarinic and nicotinic receptors.
- Serotonin
- Acetylcholine
- Dopamine
7An Optic chiasm lesion, usually related to pituitary tumor,will result in____________with loss of the temporal or lateral visual field from each eye
- Contralateral homonymus hemianopsia
- Bitemporal Hemianopsia
8is a visual field defect that affects the opposite side of the eye from the side of a brain lesion.
- bitemporal hemianopsia
- contralateral homonymous hemianopsia
9CN III damage that results to inability to raise the eyelid on the affected side
- Ptosis
- Anisocoria
- Mydriasis
10A CN III palsy would result in a dilated pupil or __________ on the affected side
- Ptosis
- Mydriasis
- Anisocoria
11A CN III palsy would results in an unequal pupil size or ___________ with the affected pupil wider than the non affected side
- Ptosis
- Mydriasis
- Anisocoria
12Is a pathological condition related to CN V function and characterized by brief but repeated sharp pain in the distributions of the Trigeminal nerve often accompanied by motor tics of facial muscles ( through CN VII) which occur reflexively
- Tic Duoluoreux
- Bell's Palsy
- Stroke
13A lesion to CN ____ will result in anaesthesia and loss of general senses of the face and anterior head on the affected side, including the Ipsilateral corneal sensation. Therefore both Ipsilateral and consensual corneal reflex will be lost
14paralysis of upper and lower face on the affected side occurs.
- tic duoluoreux
- Bell's palsy
- stroke
15Failure of sound conduction to the cochlea
- (Pure Word) or Cortical Deafness
- Conductive Deafness
- Semineural Deafness
16due to failure of action potential procedure or transmission due to disease of the cochlea, cochlear nerve, or cochlear central connections.
- Sensorineural deafness
- Cortical deafness
- Conductive deafness
17a bilateral or dominant posterior temporal lobe( auditory cortex) lesion produces a failure to understand spoken language despite preserved hearing
- Sensorineural deafness
- Cortical deafness
- Conductive deafness
18Sensation of ringing,buzzing ,pulsing, hissing, or singing quality.
19These cranial nerve forms the gag reflex
- CN 9 and 10
- CN 2 and 3
- CN 4, 5 and 7
20The person with an ____________ nerve lesion would exhibit the unique combination of weakness of the neck to the opposite side and weakness/paralysis in elevating the scapula in the ipsilateral side.
- Spinal Accessory
- Glossopharyngeal
- Trigeminal
21Lesion to this cranial nerve results in paralysis of the tongue with significant difficulty with speech, chewing and swallowing
- CN XII(Hypoglossal)
- CN X(Vagus)
- CN XI(Spinal Accessory)
22You directed the pen light on the L eye and the L pupil constricted but the R eye did not constrict, what is the CN affectation and its laterality
23most common primary tumor
- Astrocytoma
- Ependymoma
- Oligodendroglioma
24Astrocytoma Grade- less common low-grade astrocytomas including the psilocybin type
- Grade I
- Grade IV
- Grade II
- Grade III
25Astrocytoma Grade- anaplastic astrocytomas
- Grade II
- Grade III
- Grade I
- Grade IV
26Astrocytoma Grade- Diffuse types(fibrillation, protoplasmic and gemistocytic
- Grade III
- Grade II
- Grade I
- Grade IV
27Astrocytoma Grade- the most malignant type- glioblastoma occurs most frequently and widely infiltrates surrounding tissues
- Grade II
- Grade I
- Grade IV
- Grade III
28Occurs anywhere throughout the ventricular system and spinal canal, but is particularly common in the 4th ventricle and Caudia equina
- Ependymoma
- Astrocytoma
- Oligodendroglioma
29Rare tumor and uncommon cause of hydrocephalus
- Astrocytoma
- Ependymoma
- Choroid Plexus Papilloma
30Arises from arachnoid granulations
- Schwannoma
- Ependymoma
- Meningioma
31AKA neurolimmoma or neurinoma is a slow growing tumor of schwann cells
- Ependymoma
- Schwannoma
- Meningioma
32Tumor of schwann cells , fibrolasts and perineureal-like cells producing a fusiform expansion through which nerve fibers run.
33BA for Primary Somatosensory Cortex
34BA for primary visual cortex
35BA for primary auditory cortex
36BA for Broca's area/ motor speech programming
37is used to describe a complete absence of the sense of smell.
- Agraphia
- Anosmia
- Aphasia
- Apraxia
38Abnormal visual acuity in which the person cannot see clearly at distances
- Cataracts
- Hyperopia(farsightedness)
- Myopia (nearsightedness)
39Abnormal visual acuity in which the person can see most clearly at distances but can not see things up close.
- Cataracts
- Myopia(nearsighted)
- Hyperopia(farsighted)
40Abnormal Visual Acuity in which the lens of the eyes becomes cloudy or opaque, it also allow less light from the environment to reach the retina
41A patchy or sporadic distribution of visual field loss can occur from the patchy CNS demyelination of
multiple sclerosis.
- Contralateral Homonomous Hemianopsia
- Macular Degeneration
- Scotoma
- Hemianopsia
42You directed the pen light on the L eye and it did not constrict however the R eye constricted , what is the nerve affectation and the laterality
43describes an affected eye that is deviated laterally
- Diplopia
- Pseudostrabismus
- Internal Strabismus
- External Strabismus
44describes an affected eye that is medially deviated
- Internal Strabismus
- Diplopia
- Pseudostrabismus
- External Strabismus
45If the eyes appear to be differently aligned but the reflection of room lights are similarly placed on each cornea.
- Internal strabismus
- Pseudostrabismus
- Diplopia
- External strabismus
46inward turning of the eye
- Esotropia
- Hypertropia
- Exotropia
- Hypotropia
47Outward turning of the eye
- Hypertropia
- Hypotropia
- Exotropia
- Esotropia
48Upward turning of the eye
- Esotropia
- Hypertropia
- Hypotropia
- Exotropia
49Location of Weber Syndrome
- Tegmentum of the midbrain
- Lateral pons
- Bilat. basal pons
- Medial Basal Midbrain
- Lateral medulla
50Location of Benedict syndrome
- Medial Basal Midbrain
- Lateral medulla
- Lateral Pons
- Bilat. basal pons
- Tegmentum of the midbrain
51Locked in Syndrome Location
- Lateral Medulla
- Bilat. Basal Pons
- Tegmentum of the midbrain
- Lateral pons
- Medial Basal Midbrain
52Millard-Gubler Syndrome Location
- Lateral Pons
- Medial Basal Midbrain
- Tegmentum of the midbrain
- Bilat. Basal Pons
- Lateral Medulla
53Wallenburg Syndrome Location
- Bilat. Basal Pons
- Lateral Pons
- Tegmentum of the midbrain
- Lateral Medulla
- Medial Basal Midbrain
54What cranial nerve supplied the Lateral Rectus muscles of the Eye
55What Cranial nerve supplies the superior oblique muscles of the eye
- Cranial Nerve 4
- Cranial Nerve 6
- Cranial Nerve 3
56What Cranial Nerve supplies the Medial rectus, Inferior Oblique, Superior Rectus, and Inferior Rectus muscles of the eye
- Cranial 6
- Cranial Nerve 3
- Cranial 4
57an illusion of rotatory movement due to disturbed orientation of the body in space. The sufferer may sense that the environment is moving. Vertigo may result from disease of the labyrinth,
vestibular nerve or their central connections
58Transient attacks of vertigo, associated with a change in head position
- Vestibular Neuritis
- Benign Paroxysmal Positional Vertigo
- Meneire's Disease
59You noticed the pt. has a difficulty elevating their L eye( look upward) , what muscle is affected?
- Inferior Oblique
- Superior Rectus
- Inferior Rectus
- Superior Oblique
60You noticed the pt. L eye is elevated and adducted, what eye muscles are weak?
- L Inferior Oblique
- L inferior Rectus
- L Superior Rectus
- L Superior Oblique
61You noticed the pt. eye is medially deviated, what eye muscle is weak?
- Superior Oblique
- Lateral Rectus
- Inferior Oblique
- Medial Rectus
62You noticed the pt. eye is laterally deviated , what muscles are weak?
- Lateral Rectus
- Medial Rectus
- Superior Oblique
- Inferior Oblique
63Benzodiazepines used to treat insomnia , except:
- Triazolam
- Estazolam
- Zolpidem
- Temazepam
- Flurazepam
- Quazepam
64Melatonin receptor agonist:
65Tricyclic antidepressant
- Doxepin
- Eszopicione
- Souvorexant
66Orexin receptor agonist:
- Lemborexant
- Ramelteon
- Zoldipem
- Doxepin
67promotes wakefulness via excitatory effects on the nuclei of the RAS and inhibitory effects on the sleep-active projection neurons of the
VLPO
- Histamine
- Orexin
- Serotonin
- Norepinephrine
68It is predominantly located in the locus ceruleus of the brain stem.These neurons fire during wakefulness, diminish activity during NREM sleep, and are quiet during REM sleep.
- Melatonin
- Glutamate
- Norepinephrine
- Serotonin
69Associated with difficulty in initiating and maintaining sleep, characterized by frequent awakening or problems returning to sleep after awakenings, as well as early-morning awakening
with inability to return to sleep.
- Hypersomnolence
- Narcolepsy
- Insomnia
70Excessive sleepiness with recurrent periods of sleep or lapses into sleep within the day lasting for more than 9 hours per day and has difficulty being fully awake after abrupt awakening.
- Narcolepsy
- Hypersomnolence
- Insomnia
71Recurrent periods of an irrepressible need to sleep,lapsing into sleep, or
napping occurring within the day.
- Hypersomnolence
- Narcolepsy
- Insomnia
72Pressure for sleep builds up in our body as our
time awake increases
- Homeostatic Sleep Drive
- Circadian Rhythm
73refers to the internal clock in humans that regulates sleep–wake cycles.
- Circadian rhythm
- Homeostatic Sleep Drive
74Unusual behaviors during sleep, such as sleepwalking,sleep talking, or night terrors
- Parasomnias
- Insomnia
- Hypersomnolence
75Presents with pauses in breathing during sleep, often accompanied by snoring