MYCOBACTERIA

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1
rod-shaped, aerobic bacteria that do not form spores
mycobacteria
2
has a distinctive cell wall that allows acid fast staining, has drug resistance and pathogenicity. Has a waxy, water-resistant layer
mycobacteria
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used to identify mycobacterium species and some species of nocardia
acid-fast stain
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once stained with carbolfuchsin and treated with acid-alcohol, remain pink or red because they retain carbolfuchsin stain
acid fast bacteria
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when stained and treated the same way and stained with methylene blue, appear blue because they lose the carbolfuchsin stain and are then able to accept the methylene blue stain
non-acid fast bacteria
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typical mycobacteria
mycobacterium tuberculosis
mycobacterium leprae
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also known as koch's bacillus, despite being preventable and curabledisease, 1.5 million people die from it each year - making it the world's top infectious killer
mycobacterium tuberculosis
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mode of transmission of mycobacterium tuberculosis
person to person by coughing
other activities that cause the organism to be aerosolized
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manifestation of mycobacterium tuberculosis
weight loss, fatigue, productive cough, fever, night sweats, hemoptysis
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happens when patients already have large cavitary lesions in the lungs
hemoptsis
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manifestations of primary tuberculosis
asymptomatic (90-95% cases)
mild flu-like illness
rarely pleural effusion
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manifestations of reactivation tuberculosis
fever, chills, night sweats, fatigue, appetite loss, weigh loss, pleuritic chest pain, dry cough, prolonged cough producing purulent sputum, hemoptysis - suggesting advanced tb
crecipitations during lung auscultation
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TB disease that occurs in places other than the lungs, such as the brain, kidney, or the lymph nodes
extrapulmonary tuberculosis
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treatment for mycobacterium tuberculosis
rifampin, ethambutol, streptomycin, pyrazinamide, isoniazid for 2 months, followed by isoniazid and rifampin for 4 motnhs
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other term for mycobacterium leprae
leprosys, hansen's disease
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it attachs the skin, nerve endings. Can be seen in a oakisade arrangement
mycobacterium leprae
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only bacteria that infects PNS
mycobacterium leprae
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types of mycobacterium leprae
tuberculoid
lepromatous
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cause mascular lesions with loss of sensation. Postive on lepromin test
tubeculoid
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has leonine appearance, disfiguring types. Negative on lepromine test
lepromatous
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treatment for mycobacterium leprae
dapsone
clofazimin
rifampicin
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vaccine that is found to be somewhat protective against leprosy
bacillus calmette-guerin (BCG)
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atypicap bacteria
mycobacterium avium complex
mycobacterium kansasii
mycobacterium scrofulaceum
mycobacterium marnum
mycobacterium ulcernans
mycobacterium bovis
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three species of mycobacterium avium complex
mycobacterium avium
mycobacterium chimaera
mycobacterium disseminated
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clinical manifestation of mycobacterium avium complex
disseminated in immunocompromised patients
may also cause lymphadenitis
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MOT of mycobacterium avium complex
inhalation
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treatment for pulmonary disseminated MAC infections:
macrolide
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treatment for more severe cases of MAC
IV aminoglycoside
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a photochromagen that has tap water as the major environmental reservoir
mycobacterium kansasii
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clinical manifestation of mycobacterium kansasii
TB-like disease
extrapulmonary infections including lymphadenitis, skin and soft tissue infection, pericarditis
31
treatment for disease caused by mycobacterium kansasii
rifampicin
combination of rifampicin, ethambutol, and isoniazid
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