Applications 8
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1
X = osmolarity
Concentration X Osmotic coefficent= osmolarity
2
X = Effective osmotic pressure
Osmotic coefficient X Reflection Coefficient = Effective osmotic pressure
3
For tonicity, we only compare effective
For tonicity, we only compare effective osmotic pressure
4
Solution will flow to the side with the higher effective
Solution will flow to the side with the higher effective osmotic pressure
5
Normal values range from to mOsm/kg for plasma
Normal values range from 275 to 295 mOsm/kg for plasma
6
If you need to replace 1 L of intersittial fluid, you would actually need to add liters because that space is the .
If you need to replace 1 L of intersittial fluid, you would actually need to add 4 liters because that space is 1/4 the extracellular space.
7
For hypovolemia/Hypotension (isotonic correction), you can correct with isotonic saline
For hypovolemia/Hypotension (isotonic correction), you can correct with 4 L isotonic saline 
8
For hypovolemia/hypotension correcting with
(hypotonic correction) you would need to correct. Not ideal because overall osmolarity
(hypotonic correction) you would need to correct. Not ideal because overall osmolarity
For hypovolemia/hypotension correcting with
(hypotonic correction) you would need more than 4 L to correct. Not ideal because lowering overall osmolarity
(hypotonic correction) you would need more than 4 L to correct. Not ideal because lowering overall osmolarity
9
For hpovolemia/hypotension correcting with
(hypertonic correction), you would need . Not ideal bceaue it overall osmolarity
(hypertonic correction), you would need . Not ideal bceaue it overall osmolarity
For hpovolemia/hypotension correcting with
(hypertonic correction), you would need less than 4 L. Not ideal bceaue it raises overall osmolarity
(hypertonic correction), you would need less than 4 L. Not ideal bceaue it raises overall osmolarity