Pharmacoeconomics

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1
Economics
the study of how people use their scare resources to satisfy their unlimited wants/incentives
2
Health economics
the branch of economics that focuses on issues related to efficiency, effectiveness, value, and behavior in the production and consumption of health and healthcare
3
What is pharmacoeconomics (PE) or economic evaluation?
the process that identifies, measures, and compares the costs, risks, and benefits of pharmaceutical products, services, or programs
4
Economic evaluation
-determines which alternative products the best health outcome for the resources invested
-attempts to find if the added benefit of a product is worth the added costs of the product
-compares costs vs. benefits/consequences of alternatives
-sub-discipline of health economics
5
Pharmacoeconomic studies serve to...
guide optimal healthcare resource allocation, in a standardized and scientifically grounded manner
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Before proceeding with a pharmacoeconomic study, what three questions should be answered?
-can it work? does it do more good than harm to society?--answers efficacy
-does it work? does it do more good than harm to those offered it?--answers effectiveness or usefulness
-Is it reaching those who need it? accessible to those who could benefit from it?--answers availability/access
7
The US spent how much on health care in 2019?
\$3.8 trillion (17.7% of GDP)
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How much of total healthcare expenditures were prescription drugs?
about 9%
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Pharmacoeconomics evaluate the value of...
healthcare received given the costs of care
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Pharmacoeconomics (PE) helps determine best treatment for patient, depending on...
demographic, clinical, and economic considerations
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PE helps determine best...offering
service/program
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PE helps determine...for a specific patient population
cost effective options:
-develop drug use guidelines for insurance coverage
-determine medication list on formulary and co-pay amount
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What is pharmacoeconomics important?
-escalating healthcare expenditures
-rapid development in medical technology
-changes in reimbursement incentives
-changes in clinical practice
-limited healthcare resources
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What are the five basic types of PE studies?
-cost-minimization analysis (CMA)
-cost-effectiveness analysis (CEA)
-cost-consequence analysis (CCA)
-cost-utility analysis (CUA)
-cost-benefit analysis (CBA)
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What do the five basic types of PE studies measure?
cost in dollars
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What is the difference in the five basic types of PE studies?
how the health outcomes are measures and compared
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Perspective
an economic term that describes whose costs are relevant based on the purpose of the study
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Who bears the costs and benefits of healthcare?
-society
-health-care providers (hospital, clinic)
-payer (medicaid, private insurance)
-Individual patients
-employer
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What are societal's costs of primary concern?
-all direct medical and nonmedical costs: hospitalization, long-term care, home care, social welfare services
-productivity losses
-Intangible costs
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What are health care provider's costs of primary concern?
include actual costs to treat patient
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What are payer perspective's costs of primary concern?
average reimbursement costs
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What are patients' costs of primary concern?
costs to patient: patient out of pocket costs, deductible, copays, coinsurance, lost wages, transport
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What are employers' costs of primary concern?
-all insurable direct costs
-productivity losses
-disability
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CMA
-outcome measurement: proven identical or shown to be equivalent in all relevant aspects
-decision rule is lowest monetary cost
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CBA
-outcome measurement: all outcomes translated in monetary units
-decision rule: net monetary gain, B>C
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CEA
-outcome measurement: nonmonetary physical units of effectiveness
-decision rule: CE ratios using incremental
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CUA
-outcome measurement: utility values and quality adjusted life years (QALYs)
-decision rule: cost per QALY
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CCA
-outcome measurement: combination of quality of life and natural units
-decision rule: choice left up to decision maker
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What are the applications of PE?
-individual patient care
-formularytilization management
-disease management
-resource allocation
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T/F? PE's only goal is cost-containment.
false. may result in it but not only goal
31
Full PE analysis considers...
clinical, economic, and humanistic outcomes, not just cost containment
32
T/F? PE means drug utilization evaluation (DUE).
false. DUE focuses on assessing appropriateness of drug use and may use quantitative and/or qualitative approaches
33
T/F? PE means outcomes research.
false. outcomes research is a broad discipline that involves evaluating the impact of healthcare interventions and could be clinical, economic, or humanistic
34
T/F? Cost savings means cost benefit analysis.
false. CBA includes all benefits by incorporating individual preferences using contingent valuation or willingness to pay method
35
Studies measuring only costs savings are in effect...since they do not incorporate all benefits based on individual preferences
cost analyses
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