All cards
1
What is Rh Immune Globulin (RhIG)?
- a pharmaceutical drug that contains anti-D ab
- given to Rh negative mothers who are KNOWN to be negative for allo anti-D AND who have been potentially exposed to Rh+ RBCs (Rh+ baby)
- given to Rh negative mothers who are KNOWN to be negative for allo anti-D AND who have been potentially exposed to Rh+ RBCs (Rh+ baby)
2
How is RhIG administered?
intramuscular injection via a pre-measured syringe (1mL in volume) with attached needle
3
How many doses are given in RhIG?
1. Micro Dose
2. Full Dose
2. Full Dose
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What are the indications in using the MICRO dose RhIG?
after abortion, miscarriage, or termination of ectopic pregnancy
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What is the administration for MICRO dose RhIG?
at 12 weeks gestation (antepartum)
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How much RhIG is in the MICRO dose?
- micro dose = 50 µg of anti-D
- protects against 2.5 mls of Rh+ RBCs or 5 mls of Rh+ WB
- protects against 2.5 mls of Rh+ RBCs or 5 mls of Rh+ WB
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What are the indications for the FULL dose RhIG?
after amniocentesis / cordocentesis, abdominal trauma during pregnancy, antepartum, antepartum hemorrhage, or postpartum
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When is the FULL dose RhIG administered?
- following an abortion or miscarriage after 12 weeks gestation
- ≥ 28 weeks gestation (antepartum)
- Within 72 hours postpartum:
❖ When infant is Rh positive OR the fetus Rh is unknown, e.g., fetal demise / stillborn, miscarriage, etc.
❖ The mother has not developed an allo-anti-D
- ≥ 28 weeks gestation (antepartum)
- Within 72 hours postpartum:
❖ When infant is Rh positive OR the fetus Rh is unknown, e.g., fetal demise / stillborn, miscarriage, etc.
❖ The mother has not developed an allo-anti-D
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What is the FULL dose of RhIG?
Full dose = 300 µg of anti-D; protects against 15 ml of Rh+ RBCs or 30 mls of Rh+ WB
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What is the calculation for how much RhIG to give?
Fetal cells vol (from KB Test result) / 30 = # syringes given
❑ When calculating the # of RhIG vials, include 1 decimal place, i.e., X.X
❑ Rounding up or down:
➢ If the decimal number is < 0.5 - round down the calculated value, e.g., 2.2 = 2
➢ If the decimal number is ≥ 0.5 - round up the calculated value, e.g., 2.7 = 3
❑ Because this is a "calculation", it is only an "estimate". Therefore, always add 1 to your calculations to ensure adequate dose, e.g., calculated dose is 2 + 1 = 3; calculated dose is 3 + 1 = 4
❑ When calculating the # of RhIG vials, include 1 decimal place, i.e., X.X
❑ Rounding up or down:
➢ If the decimal number is < 0.5 - round down the calculated value, e.g., 2.2 = 2
➢ If the decimal number is ≥ 0.5 - round up the calculated value, e.g., 2.7 = 3
❑ Because this is a "calculation", it is only an "estimate". Therefore, always add 1 to your calculations to ensure adequate dose, e.g., calculated dose is 2 + 1 = 3; calculated dose is 3 + 1 = 4
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What is the Rh Factor Sensitization Prevention?
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Besides the RhIG intramuscular syringe, what other treatments are there?
1. IV RhIG given when there is accidential transfusion of Rh+ given in large blood volume
2. Treatment of ITP
2. Treatment of ITP
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When is IV RhIG administered instead of intramuscular RhIG?
- when blood volume is larger than 30 mLs
- ex. WinRho - pharmaceutical drug
- BB can calculate amount needed based on quanitity of Rh+ RBCs transfused
- ex. WinRho - pharmaceutical drug
- BB can calculate amount needed based on quanitity of Rh+ RBCs transfused
14
What is ITP?
- Immune thrombocytopenia purpura (ITP)
- a rare autoimmune disorder that occurs when the body's immune system
destroys platelets, which are blood cells that help blood clot
- results in petechiae
- a rare autoimmune disorder that occurs when the body's immune system
destroys platelets, which are blood cells that help blood clot
- results in petechiae
15
What is the treatment of ITP?