Antimicrobial Drugs

the use of drugs to treat a disease

interferes with the growth of microbes within the host

Substances produced by a microbe that, in small amounts, inhibits another microbe

a drug that kills harmful microbes without damaging the hosts

Bacteria (over half orginate from Streptomyces)

an antibiotic that is effective against a wide range of both gram positive and/or gram negative bacteria

Bactericidal

Bacteriostatic

Polymyxins

Penecillian, Cephalosporins, Vancomycin, Bacitracin, Monobactams

Sulfonamides, Trimethoprim

Quinolones

Rifampin, Pyronins

Chloramphenicol, macrolides (erythromycin), clindamycin, oxazolidinones (linezolid), streptogramines (synercid); Aminoglycosides (gentmicin), tetracyclines (doxycycline)

Inhibition of Ergosterol Synthesis (membrane), cell wall synthesis, synthesis of B-glucan, nucleic acids, microtubules

Cytosine analog interferes with RNA synthesis

Azoles- Miconazole, triazole