1What is the function of the heart?
The heart acts as a transport system pump that circulates blood through pulmonary and systemic circuits.
2What does the right side of the heart do?
Receives deoxygenated blood from the body and pumps it to the lungs via the pulmonary circuit.
3What does the left side of the heart do?
Receives oxygenated blood from the lungs and pumps it to the body via the systemic circuit.
4How does the structure of the ventricles relate to their function?
The left ventricle has thicker walls to generate higher pressure for systemic circulation; the right ventricle is thinner for low-pressure pulmonary circulation.
5What is the pulmonary circuit?
Short, low-pressure system that carries blood from the right ventricle to the lungs and back to the left atrium.
6What is the systemic circuit?
Long, high-pressure system that carries oxygenated blood from the left ventricle to the body and returns deoxygenated blood to the right atrium.
7What is the pathway of blood through the heart?
SVC/IVC/Coronary sinus → Right atrium → Tricuspid valve → Right ventricle → Pulmonary semilunar valve → Pulmonary trunk → Pulmonary arteries → Lungs → Pulmonary veins → Left atrium → Mitral valve → Left ventricle → Aortic semilunar valve → Aorta → Body.
8What are the atrioventricular valves and their function?
Tricuspid and mitral valves prevent backflow into atria when ventricles contract.
9What are the semilunar valves and their function?
Pulmonary and aortic semilunar valves prevent backflow from major arteries into ventricles.
10What causes the “lub-dub” heart sounds?
Lub: AV valves closing at start of systole; Dub: SL valves closing at start of diastole.
11What is a heart murmur?
An abnormal heart sound caused by obstructed or incompetent valves.
12What are pectinate muscles?
Ridges in atrial walls that help atria contract efficiently.
13What are papillary muscles and their function?
Muscles in ventricles that anchor chordae tendineae to prevent valve flaps from inverting.
14What are chordae tendineae?
Fibrous cords that prevent AV valve cusps from everting into atria during ventricular contraction.
15What is the foramen ovale (fossa ovalis in adults)?
Fetal opening between atria that allows blood to bypass the lungs before birth.
16What is the pericardium?
Double-walled sac surrounding the heart that protects and anchors it.
17What are the layers of the pericardium?
Fibrous pericardium (outer) and serous pericardium (parietal and visceral layers).
18What are the three layers of the heart wall?
Epicardium (outer), myocardium (muscle), endocardium (inner lining).
19What is pericarditis?
Inflammation of the pericardium causing friction rub.
20What is cardiac tamponade?
Compression of the heart due to excess fluid in the pericardial space.
21What is angina pectoris?
Chest pain caused by reduced blood flow (ischemia) to the myocardium.
22What is myocardial infarction?
Prolonged coronary blockage causing cardiac cell death (heart attack).
23What is ischemia?
Reduced blood flow to tissue, causing oxygen deprivation.
24What is coronary circulation?
Functional blood supply to the heart muscle itself.
25What are the main coronary arteries?
Left coronary artery (anterior interventricular & circumflex branches) and right coronary artery (right marginal & posterior interventricular branches).
26What collects venous blood from the heart?
Cardiac veins empty into the coronary sinus, which drains into the right atrium.
27What is the cardiac conduction system?
Network of autorhythmic cells that initiate and distribute impulses for coordinated heart contraction.
28What is the function of the SA node?
Pacemaker of the heart; generates impulses at ~75 beats per minute.
29What is the function of the AV node?
Delays impulses (~0.1 sec) to allow atrial contraction before ventricular contraction.
30What is the function of the AV bundle (Bundle of His)?
Only electrical connection between atria and ventricles.
31What do Purkinje fibers do?
Spread impulses through ventricular walls for coordinated contraction.
32What is the function of the vagus nerve?
Provides parasympathetic input to slow heart rate.
33What does the P wave on an ECG represent?
Atrial depolarization (SA node activity).
34What does the QRS complex on an ECG represent?
Ventricular depolarization and atrial repolarization.
35What does the T wave on an ECG represent?
Ventricular repolarization.
36What does an elevated or depressed ST segment indicate?
Cardiac ischemia.
37What is systole?
Period of heart contraction.
38What is diastole?
Period of heart relaxation.
39What is cardiac output (CO)?
Amount of blood pumped by each ventricle per minute; CO = HR × SV.
40What is stroke volume (SV)?
Volume of blood pumped by one ventricle per beat (~70 mL).
41What is the Frank-Starling law of the heart?
The more cardiac muscle cells are stretched, the stronger they contract.
42How does exercise affect cardiac output and ECG?
Increases heart rate and shortens intervals; improves efficiency.
43What are intercalated discs and their function?
Specialized junctions with desmosomes and gap junctions that allow cardiac cells to contract as a coordinated unit.
44How does cardiac muscle differ from skeletal muscle?
Short, branched, single-nucleated cells with many mitochondria; contracts as a functional syncytium; depends on aerobic respiration.