COVID-19

Question 1

Coronaviruses are enveloped (DNA/RNA) viruses.

Accepted Answer

RNA

Question 2

Human coronaviruses typically cause ___________________________ and may cause ___________________________ infections.

Accepted Answer

common colds and lower respiratory tract infections

Question 3

In 2019, a novel coronavirus labeled SARS-CoV-2 spread, causing much more severe respiratory illness than its predecessors. The disease resulting from SARS-CoV-2 is called ________________.

Accepted Answer

COVID-19

Question 4

What is the preferred test for COVID-19 detection?

Accepted Answer

Nucleic acid amplification test (PCR) from upper respiratory tract (nasopharyngeal, nasal, or oropharyngeal)

Question 5

What populations are at higher risk for progressing to severe COVID-19?

Accepted Answer

- Age > 65 - T2D - Respiratory disease - Cancer - Renal disease - Obesity - Sickle cell anemia - Pregnancy - Transplant/Immunosuppressed

Question 6

COVID-19 Common symptoms:

Accepted Answer

- Fever - Chills - Muscle pain - Loss of taste/smell - Sore throat - SOB - Fatigue - HA

Question 7

COVID-19 Prevention:

Accepted Answer

- Vaccine - Mask/Distancing - Monoclonal antibodies (pre-exposure or post-exposure prophylaxis_

Question 8

When should Evushield (tixagevimab/cilgavimab) be used?

Accepted Answer

Age ≥ 12 who do NOT have COVID-19 and are not eligible for vaccination for health reasons

Question 9

Majority of patients infected with COVID-19 will have only mild symptoms and will not require treatment (True/False_

Accepted Answer

True

Question 10

COVID-19 Outpatient Management:

Accepted Answer

- OTC antipyretic/analgesic/antitussive - Adequate rest & fluid consumption - Paxlovid (for outpatients who are at risk of progressing to severe illness)

Question 11

Outpatients may receive these antiviral therapies if they are at risk of progressing to severe illness:

Accepted Answer

- *Paxlovid* (nirmatrelvir/ ritonavir) - Veklury (remdesivir) - Lagevrio (molnupiravir) - bebtelovimab (investigational)

Question 12

Which of the 3 has the lowest efficacy? Paxlovid, Veklury, Lagevrio?

Accepted Answer

Lagevrio

Question 13

bebtelovimab should not be used if: (2)

Accepted Answer

- hospitalized - requiring oxygen

Question 14

COVID-19 Inpatient Management:

Accepted Answer

- Supplemental oxygen (if needed)
- Remdesivir (if O2 required)
- Dexamethasone (if O2 required)
- Tocilizumab or Baricitinib (if O2 requirement increases rapidly, must be used with steroids)
- VTE prophylaxis (UFH, or continue home antithrombotic meds, unless CI'd)

COVID-19

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