1Define Gene
A unit of heredity made of DNA that influences biological traits.
2define Genetic predisposition
A biological tendency to develop a trait or behaviour.
3Define Gene-environment interaction
The idea that behaviour is influenced by the interaction between genetic factors and environmental experiences.
4what is the function of 5-htt gene
A gene involved in the transport of serotonin.
5What can a mutation within the 5-htt alelle cause?
a mutation may lead to a lower serotine transport effeiceny which may lead to consistent low mood a common behaviour of depression
6Function of serotonine
neuotransmitter that infleuces mood, emotion, sleep and agression
7Define MDD
Major depressive disorder (MDD) is a mood disoder in which characterized by persistent, intense feelings of sadness, worthlessness, and a loss of interest in activities lasting at least two weeks.
8so gene are effecting what behaviour?Define
Genes may infleuce depresive behaviour
9what study shows this?
Caspi et al (2003)
10Aim of caspi et al (2003)
to inevstigate the effect of the size of the 5-HTT gene on likeyhood of MDD
11Procedure of caspi et al (2003)
Correlational study, logitiional, quasi
opporunity sample 847 new zealanders that were a part of a cohort of participants who were part of another longitudinal study, When they were 21 using genetic testing to test for varients of the 5-HTT gene and used self-reported measures to measure the exposure to stressful life events and symptoms of depression until the age for 26
3 groups
2 long allels
1 short and 1 long allele
2 short allele
12Results of caspi et al 2003
Paritcipents with one or two short alleles were more likley to develop MDD symptoms following stressful life events.
Participents with 2 long alleles were less likley to develope MDD symptoms
This suggests the short alleles is associated with reduced efficiency in serotonin transport, which may affect mood regulation.
13Conclusion of caspi et al 2003
Genes don't directly cause behvaiour but influece the likleyhood of development certain behaviours such as depressive symptoms, in response to environmental stress. Therefore, genes may affect behaviour through gene–environment interaction,