Simulations

Acamprosate
Disulfiram
Naltrexone

The number of associated symptoms:
Mild:2-3
Moderate: 4-5
Severe: 6+

Larger amounts consumed over a longer period than intended
Persistent desire or unsuccessful efforts to cut down or control use
>time spent on activities to obtain, use, or recover from effects
Craving or strong desirerge to use
Recurrent use resulting in failure to fulfill major obligations
Continued use despite having recurrent problems that are exacerbated by use
Important activities are given up or reduced because of use
Recurrent use inn situations in which it is physically hazardous
Use is continued despite knowledge of having a phusical or psychological problem caused or exacerbated by use
Tolerance
Withdrawal

Autonomic hyperactivity
>hand tremor
Insomnia
Nausea or vomiting
Transient visual, tactile, or auditory hallucinations or illusions
Psychomotor agitation
Anxiety
Generalized tonic-clonic seizures

Sedative, hypnotic, or anxiolytic withdrawal

Oxazepam
Diazepam
Cloraepate
Chlordiazepoxide

Dysphoric mood
Fatigue
Vivid, unpleasant dreams
Insomnia or hypersomnia
Increased appetite
Psychomotor retardation or agitation

Irritability, anger, or aggression
Nervousness or anxiety
Sleep difficulty (insomnia, disturbing dreams)
Decreased appetite or weight loss
Restlessness
Depressed mood
Physical Symptoms: abdominal pain, shakiness/tremors, sweating, fever, chills, or headache

Irritability, frustration, anger
Anxiety
Difficulty concentrating
Increased appetite
Restlessness
Depressed mood
Insomnia

Varenicline
Bupropion
Nicotine replacement patches

Dysphoric mood
Nausea or vomiting
Muscle aches
Lacrimation or rhinorrhea
Pupillary dilation, piloerection, or sweating
Diarrhea
Yawning
Fever
Insomnia

Naltrexone
Buprenorphine
Methadone

Evidence of a causative AD genetic mutation from family history or genetic testing
Clear evidence of decline in memory/learning and one other cognitive domain
Steadily, progressive,gradual decline in cognition
No evidence of mixed etiology

donepezil
memantine
galantamine
rivastigmine

Criteria for a mild or major neurocognitive disorder
Onset is insidious and has a gradual progression
Core features:
-Fluctuating cognition w/ pronounced variations in attention/alertness
-Recurrent visual hallucinations (well formed and detailed)
-Spontaneous features of parkinsonism w/ onset after the development of cognitive decline
*May also have REM sleep behaviors and severe neuroleptic sensitivity (developing EPS and neuroleptic malignant syndrome)

Criteria for a mild or major neurocognitive disorder
Onset is insidious and has a gradual progression
Core features:
-Behavioral: disinhibition, apathy, loss of sympathy/empathy, perseveratioin, stereotyped or compulsiveitualistic behaviors, hyperorality & dietary changes
-Prominent decline in social cognition and/or executive abilities
-Language: decline in ability, speech production, word finding, object naming, grammar, or word comprehension
-Some sparing of learning/memory and perceptual-motor function

Enduring pattern of inner experience & behavior that deviates markedly from the expectations of the individual's culture and is manifested by:
-cognition
-affectivity
-interpersonal functioning
-impulse control
The pattern is:
-inflexible & pervasive across a broad range of personal & social situations
-leads to clinically significant distress or impairment in function
-stable & long in duration w/ onset in adolescence or early adulthood

-Grandiosity
-Need for admiration
-Lack of empathy
-Entitlement
-Takes advantage of others
-Envy
-Arrogant

-Distrust & suspiciousness of others
-Preoccupation w/ unjustified doubts about loyalty/trust
-Reluctant to confide in others
-Reads into hidden demeaning or threatening meanings of remarks or events
-Persistent grudges
-Quick to react in anger or counterattack
-Recurrent suspicions w/o justification regarding fidelity of partner

-Excessively emotional
-Attention seeking
-Need to be center of attention
-Inappropriate sexually seductive or provacative behavior
-Rapid shifts of shallow expressions of emotions
-Physical appearance is used to draw attention to self
-Speech is impressionistic and lacking detail
-Dramatic & exaggerated expression of emotion
-Suggestible
-Considers relationships more intimate than they are

-Pervasive pattern of detachment from social relationships
-Restricted range of expression of emotions in interpersonal settings
-Neither desires nor enjoys close relationships (even family)
-Solitary activities
-Little interest in sexual experiences w/ another person
-Little pleasure in activities
-Lacks close friends other than 1st degree relatives
-Appears indifferent to the praise or criticism of others
-Shows emotional coldness, detachment, or flat affect

-Pervasive pattern of instability of interpersonal relationships, self-image, and affect
-Marked impulsivity
-Frantic efforts to avoid real or imagined abandonment
-Pattern of unstable & intense interpersonal relationships w/ extremes of idealization & devaluation
-Indentity disturbance: unstable self-image or sense of self
-Impulsive in areas that are self-damaging (2+)
-Recurrent suicidal behavior, gestures, or threats or self-mutilating behavior
-Affective instability r/t marked reactivity of mood
-Chronic feelings of emptiness
-Inappropriate, intense anger or difficulty controlling anger
-Transient, stress-related paranoid ideation or severe dissociative symptoms

-Pervasive pattern of social/interpersonal deficits marked by acute discomfort w/ close relationships as well as cognitive/perceptual distortions & eccentric behavior
-Ideas of reference
-Odd beliefs or magical thinking
-Unusual body percentions (bodily illusions)
-Odd thinking/speech
-Suspiciousness or paranoid ideation
-Inappropriate or constricted affect
-Behavior or appearance is odd, eccentric, or peculiar
-Lack of close friends
-Excessive social anxiety that does not diminish w/ familiarity & tends to be associated w/ paranoid fears rather than negative judgments about self

Pervasive pattern of disregard for & violation of the rights of others, occurring since age 15
-Failure to conform to social norms w/ respect to lawful behaviors (multiple arrests)
-Deceitfulness (lying, use of aliases, conning others)
-Impulsivity or failure to plan ahead
-Irritablity & aggressiveness (fights/assults)
-Reckless disregard for safety of others/self
-Consistent irresponsibility (can't hold job or honor financial obligations)
-Lack of remorse
**must be at least 18 years old to dx

Pervasive & excessive need to be taken care of that leads to submissive & clinging behavior & fears of seperation
-Difficulty w/ decision making w/o an excessive amount of advice & reassurance from others
-Needs others to assume responsibility for most major areas of life
-Difficulty expressing disagreement w/ others because of fear of loss of support or approval
-Difficulty initiating projects or doing things on own
-Goes to excessive lengths to obtain nurturance & support from others; volunteering to do things is unpleasant
-Feels uncomfortable or helpless when alone r/t exaggerated fears of being unable to care for oneself
-Urgently seeks another relationship if one relationship ends
-Unrealistically preoccupied w/ fears of being left to take care on onself

-Pervasive pattern of social inhibition, feelinds of inadequacy, & hypersensitivity to negative evaluation
-Avoids activities that involve significant interpersonal contact because of fears of criticism, disapproval, or rejection
-Unwilling to get involved w/ people unless certain of being liked
-Shows restraint w/in intamate relationships because of fear of being shamed or ridiculed
-Preoccupied w/ being criticized or rejected in social situations
-Inhibition in new interpersonal situations r/t feelings of inadequacy
-Views self as socially inept, personally unappealing, or inferior to others
-Reluctant to take personal risks or engage in any new activities because they may be embarrasing

Development of emotional or behavioral symptoms in response to an identifiable stressor occurring w/in 3 months of onset
-Marked distress that is out of proportion to the severity or intensity of the stressor
-Significant impairment in functioning

Exposure to actual or threatened death, serious injury, or sexual violence
-direct exposure
-witnessing the event happen to someone else
-learning that the event happened to a close friend/family member
-experiencing repeated or extreme exposure to adverse details of the event

Presence of intrusive symptoms associated with the event/trauma
-recurrent, involuntary, & intrusive distressing memories of the event
-recurrent distressing dreams in which the content and affect of the dream are r/t the event
-dissociative reactions (flashbacks) which feels like the "real" event again
-intense of prolonged psychological distress at exposure to internal or external cues that symbolize or resemble an aspect of the event

Persistent avoidance of stimuli associated w/ the event beginning after the event
-avoidance of events to avoid distressing memories, thoughts, or feelings about the event
-avoidance of external reminders that arouse distressing memories, thoughts, or feelings about or closely associated w/ the event

Negative alterations in cognitions and mood associated w/ the traumatic events beginning or worsening after the traumatic event happened
-inability to remember important aspect of the traumatic event
-persistent & exaggerated negative beliefs or expectations about oneself, others, or the world
-persistent, distorted cognitions about the cause or consequences of the event that lead the individual to blame themselves or others
-persistent negative emotional state
-markedly diminished interest or participation in significant activities
-feelings of detachment or estrangement from others
-persistent inability to experience positive emotions

Marked alterations in arousal & reactivity associated with the traumatic events, beginning or worsening after the event
-irritable behavior & angry outbursts (verbal or physical aggression)
-reckless or self-destructive behavior
-hypervigilance
-exaggerated startle response
-problems w/ concentration
-sleep disturbance

Duration of the disturbance >1mo

Causes distress or impairment in function

sertraline
paroxetine
fluoxetine
venlafaxine

Disruption of identity characterized by 2+ distinct personality states
Disruption in identity involves marked discontinuity in sense of self & sense of agency, accompanied by related alterations in affect, behavior, consciousness, memory, perception,cognition, & sensory-motor function
Recurrent gaps in the recall of everyday events, important personal information, and events that are inconsistent w/ ordinary forgetting
Symptoms cause distress or impairment in function

Symptoms are distressing or result in significant disruption of daily life
Excessive thoughts, feelings, or behaviors r/t somatic symptoms or associated health conditions
-disproportionate & persistent thoughts about the seriousness of one's symptoms
-persistently high level of anxiety about health or symptoms
-excessive time & energy devoted to these symptoms or health concerns
Any one somatic symptom may not be continuously present, the state of being symptomatic is persistent (>6mo)

Preoccupation w/ having or acquiring a serious illness
Somatic symptoms are not present or if present are only mild in intensity
High level of anxiety about health-related behaviors or exhibits maladaptive avoidance
Illness preoccupation has been present for at least 6 months

A marked incongruence between one's experienced/expressed gender and assigned gender, of at least 6 months duration, as manifested by:
-a strong desire to be rid of one's primary and/or secondary sex characteristics because of a marked incongruence w/ one's experienced/expressed gender
-a strong desire for the primary and/or secondary sex characteristics of the other gender
-a strong desire to be of the other gender
-a strong convictioin that one has the typical feelings and reactions of the other gender
Condition is associated with significant distress or impairment in function