1Basal Metbolic Rate
Hypothyroidism:
Hyperthyroidism:
Hypothyroidism: Weight gain
Hyperthyroidism: Weight loss
2Behaviors
Hypothyroidism:
Hyperthyroidism:
Hypothyroidism: Mental sluggishness
Hyperthyroidism: Restlessness, irritability
3Cholesterol level
Hypothyroidism:
Hyperthyroidism:
Hypothyroidism: Hypercholesterolemia
Hyperthyroidism: Hypocholesterolemia
4Gastrointestinal
Hypothyroidism:
Hyperthyroidism:
Hypothyroidism: Constipation, fecal impactions
Hyperthyroidism: Diarrhea
5Proteins
Hypothyroidism:
Hyperthyroidism:
Hypothyroidism: Infections
Hyperthyroidism: Muscle proteins catabolism
6Blood glucose
Hypothyroidism:
Hyperthyroidism:
Hypothyroidism: Hypoglycemia
Hyperthyroidism: Hyperglycemia
7Vitamins
Hypothyroidism:
Hyperthyroidism:
Hypothyroidism: Vitamin B12 and folate
Hyperthyroidism: Accelerated use of vitamins
8Complications
Hypothyroidism:
Hyperthyroidism:
Hypothyroidism: Myxedema, Cretinism, Coma
Hyperthyroidism: Thyroid crisis (storm)
9refers to the hypersecretion of the parathyroid gland characterized by hypercalcemia.
Hyperparathyroidism
10Hyperparathyroidism happens due to too much activity in one or more parathyroid glands, which create what hormone?
parathyroid hormone
11Too much PTH raises ________ levels in the blood
Calcium
12PTH can stimulate kidney production of the active form of vitamin D. Which is?
calcitriol
13______ use, a drug used to treat bipolar disorder, can affect calcium levels.
Lithium
14How to diagnose Hyperparathyroidism?
Urine tests, Bone Density Test, X-ray
15What is the MNT for Hyperparathyroidism?
Phosphate blockers, HIgh fluid intake, Acid-ash and PO4 diet
16refers to the hyposecretion of the parathyroid gland characterized by the hyperirritability of the nervous system as manifested by convulsions, crumps, muscle twitching and spasm.
Hypoparathyroidism
17The post-surgery cause of hypoparathyroidism is an activating mutation of the
________________ (CASR) gene also called autosomal dominant hypocalcemia type 1.
extracellular calcium-sensing receptor
18When ___________ levels are low, it often leads to low levels of calcium in the blood as well.
Magnesium
19What is the MNT for Hypoparathyroidism?
High Calcium and Vitamin D
20Musculoskeletal
Hypoparathyroidism:
Hyperparathyroidism:
Hypoparathyroidism: Chvostek's, Trousseau's
Hyperparathyroidism: Weight loss, muscle weakness, bone pain
21Gastrointestinal
Hypoparathyroidism:
Hyperparathyroidism:
Hypoparathyroidism: Abdominal cramping, diarrhea
Hyperparathyroidism: Anorexia, nausea, constipation
22Cardiovascular
Hypoparathyroidism:
Hyperparathyroidism:
Hypoparathyroidism: Bradycardia
Hyperparathyroidism: Bounding pulse and arrhythmias
23Renal
Hypoparathyroidism:
Hyperparathyroidism:
Hypoparathyroidism: None
Hyperparathyroidism: Kidney stones, renal failure, polyuria
24a rare disorder caused by inadequate production of the steroid hormones cortisol and aldosterone by the adrenal cortex
Addison's disease
25General appearance
Hypokalemia:
Hyperkalemia:
Hypokalemia: Fatigue, restless, lethargic
Hyperkalemia: Anxious, irritable, mental confusion
26Cardiovascular/immune system
Hypokalemia:
Hyperkalemia:
Hypokalemia: Dysrhythmias, Weak, Irregular pulse
Hyperkalemia: Irregular slow pulse
27Gastrointestinal system
Hypokalemia:
Hyperkalemia:
Hypokalemia: Diminished bowel sounds, Paralytic ileus
Hyperkalemia: Abdominal cramps, Nausea, Diarrhea
28Musculoskeletal system
Hypokalemia:
Hyperkalemia:
Hypokalemia: Muscle weakness, leg cramps
Hyperkalemia: Lower-extremity weakness
29Neurologic system
Hypokalemia:
Hyperkalemia:
Hypokalemia: Paresthesias, Decreased reflexes
Hyperkalemia: None
30The layers are the zona fasciulata that secretes _______ and the zona glomerulosa that secretes ________.
Cortisol, Aldosterone
31Stimulates gluconeogenesis. Increases breakdown of protein, thereby elevating serum protein levels
Cortisol
32Increases sodium retention in kidneys with passive absorption of water. Increases renal excretion of potassium
Aldosterone
33where the adrenal glands are undamaged but cannot produce these hormones for other reasons such as due to abnormalities of the pituitary gland
Secondary Adrenal Insufficiency
34is usually caused by damage to the adrenal cortex that results from an autoimmune reaction. caused by the inability of the adrenal cortex to produce hormones such as cortisol and aldosterone.
Primary renal insufficiency
35What is the MNT of Addison's Disease?
High Na, Low K, High Kcal
36also called hypercortisolism, is a rare disorder caused by chronic exposure to excessive circulating cortisol
Cushing's Disease
37Overproduction of steroid hormone cortisol in cushing’s syndrome is caused by too much production of what hormone?
adrenocorticotropic hormone (ACTH)
38How to diagnose Cushing's Syndrome?
Low Dose Dexamethasone Suppression Test
39What is the MNT of Cushing's Syndrome/Disease?
Low Na, High K, Low Kcal
40a rare genetic disorder characterized by inability of the body to metabolize copper because of lack of ceruloplasmin, the transport protein of copper.
Wilson's Disease
41The disease may be diagnosed using a thorough clinical evaluation, a complete patient history, and specialized tests that include slit-lamp examination of the eyes that reveals the presence of ___________?
Kayser-Fleischer rings
42Wilson's Disease can be revealed through tests of the fluid portion of the blood (serum) that demonstrate low levels of _________, a copper protei.;
Ceruloplasmin
43What is the MNT for Wilson's Disease?
Copper-restricted to prevent Cu retention
44a disorder in iron metabolism characterized by the accumulation of iron in the liver, heart and pancreas. The abnormally stored iron can damage affected organs, potentially causing a variety of different symptoms.
Hemochromatosis
45Blood tests are performed to detect abnormal increased in iron levels
in the blood; elevated blood levels of an iron compound that is used as an indicator of the serum ____ levels, and increased________ saturation.
Ferritin, Transferrin
46What is the MNT for Hemochromatosis?
Fe-restricted because of increased storage of iron, Phlebotomy