1Modern Synthesis
Units of evolution are genes (mendel), mechanism of evolution is selection (darwin)
2How does genetic variation in populations occurHardy
Occurs by chance through mutation and recombination
3Evolution
Change in allele fequencies in a population over time
4Microevolution
Study of evolution at its smallest scale (population)
5Population
Localized group of organisms of the same species that are capable of interbreeding
6Allele
A version of a gene (AA, aa, Aa), humans have 2 alleles for each gene on each
7Fixed allele
No variation at a locus, common in rare species
8Gene pool
Composition of alleles for a population at a specific time, separates genes from individuals
95 ways allele frequency changes (evolution)o
1. Genetic drift (small population size)
2. Non-random mating
3. Mutation
4. Gene flow
5. Natural selection
103 ways allele frequencies do not changep
1. Meiosis
2. Independent assortment
3. Sexual reproduction
11Genetic drift
Random and unpredictable change in allele frequencies, bottleneck effect and founder effect
12How do you know evolution is occuring?
Determine if allele frequencies are actually changing (Hardy-Weinberg equation), if a population is at H-W equillibrium, evolution does not happen (rarely happens)
13How does natural selection affect genetic variation
Maintain, increase, or reduce
14How does genetic drift affect genetic variation
Reduce via loss or fixation of alleles
15How does gene flow affect genetic variation
May increase genetic variation by introducing new alleles, may decrease by removing alleles
16H-W equilibrium conditions
1. Large population
2. Random mating
3. No mutations
4. No migrations
5. No natural selection
17Bottleneck effect (genetic drift)
Large populations typically have lots of genetic variability, if most of population is killed, some genetic variability is lost (sudden environmental change)
18Founder effect (genetic drift)
Members of a population establish a new and isolated population
19When does natural selection act on genetic variation?
When it is expressed as a phenotype
20Directional selection
Favors one extreme phenotype, causes average phenotype to change in one direction
21Stabilizing selection
Favors phenotypes near the middle, maintaining average phenotype
22Disruptive selection
Favors extreme phenotypes at both ends of the phenotypic variation
234 mechanisms to maintain genetic diversity
Diploidy, heterozygote advantage, negative frequency dependent selection, neutral variation
24How does diploidy maintain genetic diversity
Diploid condition can hide genetic diversity from selection (carriers for recessive alleles), less favorable alleles can persist as heterozygous individuals
25How does negative frequency-dependent selection maintain genetic diversity
As a phenotype gets more common, it is less successful
26how does neutral variation maintain genetic diversity
Little to no impact on success. In time, neutral alleles change frequency by genetic drift.