Hormones

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1
Network of glands that secrete hormones directly into the bloodstream to regulate bodily functions
endocrine system
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Chemical signals produced by specialized cells that travel through the blood to target tissues
hormones
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Primary biological processes for which hormones are essential
growth, development, and metabolism
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The gland that controls hormone secretion and which in turn regulated by the ____
pituitary, hypothalamus
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System that in turn regulates the hypothalamus
hypothalamus
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Two types of mechanisms that regulate hormone activity
positive and negative feedback mechanisms
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Mechanism where an increase in a product leads to an elevation of the system's activity and production rate
positive feedback mechanism
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Hormones that serve as examples of the positive feedback mechanism
Gonadal, thyroidal, and adrenocortical hormones
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Mechanism where an increase in a product leads to a decrease in the system's activity and production rate
negative feedback mechanism
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Hormone that serves as an example of the negative feedback mechanism
Luteinizing hormone (LH)
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Type of negative feedback involving hormones produced in the pituitary gland acting on the hypothalamus
Long FM (Feedback Mechanism)
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Type of negative feedback involving feedback from hormones at the level of the pituitary gland
Short FM (Feedback Mechanism)
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Feedback mechanism specifically between the pituitary and the hypothalamus
Ultrashort FM (Feedback Mechanism)
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Hormones consisting of a steroid ring and formed from cholesterol
Steroid hormones
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Hormones described as large or small hydrophilic molecules
Peptide hormones
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The specific cellular location where peptide hormones are synthesized
rough ER
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The synthesis timing of steroid hormones
Synthesized when needed
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The synthesis timing of peptide hormones
Synthesized all the time
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The location of receptors for peptide hormones
cell surface
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The hormone type that binds DNA to modify transcription
Steroid hormones
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Relative speed of action for steroid hormones
Slower
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Relative speed of action for peptide hormones
Rapid/Fast
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The hormone type characterized by permanent action
Steroid hormones
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The molecular nature of steroid hormones
made up of lipid (hydrophobic)
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The molecular nature of peptide hormones
made up of protein (amino acids)
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Comparison of molecular size between peptide and steroid hormones
peptides can be large or small
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Primary precursor for all steroid hormones
cholesterol
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Precursor for Melatonin and Serotonin
Tryptophan
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Primary amino acid from which Thyroxine (T4), Triiodothyronine (T3), Epinephrine, and Norepinephrine are derived
Tyrosine
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Category of hormones that include Prostaglandins
Fatty Acid Derivatives
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Pituitary hormone responsible for sperm and egg production
Follicle Stimulating Hormone (FSH)
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Pituitary hormone responsible for protein synthesis, cell growth, and division
Growth Hormone (Somatotropin)
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The most abundant hormone in the Anterior Pituitary Gland (APG)
Growth Hormone
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Pituitary hormone responsible for the production of adrenocortical hormones by the adrenal cortex
Adrenocorticotropic Hormone (ACTH)
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Pituitary hormone responsible for the maturation of follicles, ovulation, and production of estrogen, progesterone, and testosterone
Luteinizing Hormone (LH)
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Pituitary hormone responsible for lactation
Prolactin
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The main stimulus for Prolactin release
nipple touch
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The primary Prolactin inhibitor
Dopamine
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Effect on Prolactin levels if a patient undergoes a breast exam
Increased
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Condition characterized by menstrual irregularity, infertility, galactorrhea, and amenorrhea
Hyperprolactinemia
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Hormone responsible for uterine contractions during childbirth and lactation
Oxytocin
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Hormone responsible for the reabsorption of water in distal renal tubules
ADH (Antidiuretic hormone/vasopressin)
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Hormone responsible for the production of T3 and T4 by the thyroid
Thyroid Stimulating Hormone (TSH)
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Specific thyroid hormones responsible for metabolism, growth, and development
T3 and T4
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Thyroid hormone that inhibits Ca2+ resorption
Calcitonin
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Hormone that regulates Ca2+ and phosphate levels
PTH (Parathyroid Hormone)
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Clinical result of Hyperparathyroidism
↑ PTH, ↑ Ca2+, ↓ phosphate
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Clinical result of Hypoparathyroidism
↓ PTH, ↓ Ca2+, ↑ phosphate
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Identity of the principal thyroid hormone that is 50x more concentrated than T3 and contains 4 atoms of Iodine
Thyroxine (T4)
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Status of Thyroxine (T4) regarding potency and abundance
Least potent and most abundant
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Thyroid hormone formed from deiodination of T4 by tissues, containing 3 atoms of Iodine
Triiodothyronine (T3)
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Status of Triiodothyronine (T3) regarding potency and abundance
Most potent and least abundant
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Adrenal hormone responsible for the reabsorption of Na+ in renal tubules
Aldosterone
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Adrenal hormone responsible for carbohydrate/fat/protein metabolism and suppression of inflammatory/allergic reactions
Cortisol
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Hormones released during "Fight or flight syndrome" by the adrenal medulla
Epinephrine and Norepinephrine
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Identity of the catecholamines
Epinephrine and Norepinephrine
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Primary female reproductive hormone for development of organs and secondary sex characteristics in early stages
Estrogen
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Female hormone responsible for preparation of the uterus for ovum implantation and maintenance of pregnancy
Progesterone
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Placental hormone utilized for monitoring fetal growth and development
HPL (Human Placental Lactogen)
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Placental hormone that regulates progesterone production by the corpus luteum during early pregnancy
HCG (Human Chorionic Gonadotropin)
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Placental hormone responsible for the development of fetal gonads
HCG
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Hormone that regulates Estrogen and Progesterone production by the corpus luteum and development of mammary glands
Human Placental Lactogen
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Primary hormone increased in the first trimester of pregnancy
HCG
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Timing when HCG starts to increase
8 to 11 days after conception
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Electrolyte for nerve impulses - Sequence of four elements involved in conducting electrical signals through nerves
Potassium, Sodium, Magnesium, Calcium
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Electrolyte for ECF and cell volume - Element responsible for maintaining the volume of extracellular fluid (ECF) as well as overall cell size and shape
Sodium
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Electrolyte for cardiac muscle contraction - Major extracellular cation vital for managing heart muscle contractions and balancing physiological pH levels
Potassium
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Major extracellular anion - Primary negatively charged ion in extracellular fluid that functions to maintain osmotic pressure balance
Chloride
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Blood buffering system component - Major constituent of the blood buffer system responsible for preserving charge neutrality inside the cell
Bicarbonate
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Aids in nerve and muscle contraction - Cation that assists in neuromuscular signaling and is essential for developing healthy bones and teeth
Calcium
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Fourth most abundant cation - Element classified as the body's fourth most abundant total cation and its second most abundant intracellular cation
Magnesium
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Maintains electric neutrality via interaction - Anion that acts in the plasma to balance charge via direct interactions with sodium or carbon dioxide
Chloride
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Decreased levels lead to tetany - Specific mineral whose deficiency or decreased concentrations directly trigger neuromuscular excitability or tetany
Calcium
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Aids in cell growth and repair - Nutritional mineral compound essential for cellular growth, energy processing, bone structure, and dental health
Phosphorus / Phosphate
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Growth, healing and immune function - Specific trace element necessary for optimal physical development, wound healing, and immune response activation
Zinc
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Pyruvate, arginine and superoxide metabolism - Essential trace element involved in processing pyruvate, arginine, and driving superoxide metabolic pathways
Manganese
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Energy transfer and connective tissue formation - Trace element that serves as a core cofactor for structural connective tissue generation and cellular energy transport
Copper
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Prevents peroxidation of reduced compounds - Essential micronutrient or trace element that blocks the oxidation of reduced vital compounds like glutathione
Selenium
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Energy transfer by hemoglobin and cytochromes - Functional core metal element utilized by blood hemoglobin and metabolic cytochromes to move energy and oxygen
Iron
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Part of insulin receptor - Trace element that integrates directly into the insulin receptor complex to support glucose management
Chromium
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Builds and fixes DNA and protects cells - Crucial structural mineral element that builds and fixes DNA structures while keeping cellular systems safe from damage
Sulfur
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