105 study guide

Branch of pharmacology that studies the use of biologically engineered drugs

lily

A group of varied medicinal products such as vaccines, blood products, allergenics and proteins.

Derived from life forms existing in nature, substances created using biotechnology.

Plants and animals

Artificial forms of recombinant DNA that have been created by combining or inserting one or more DNA strands into a single molecule

Louis Pasteur’s work - Penicillin in 1857

Gaucher's disease

Rheumatoid Arthritis

Neutropenia

Rheumatoid Arthritis

Anemia from cancer therapy, chronic renal failure

Chrons disease

Breast cancer

Rheumatoid arthritis

psoriasis treatment

Approximately 12 years to move a drug from the experimental sage to the pharmacy

The new drug is tested against a targeted disease through laboratory and animal study

(Investigational New Drug) Shows the results of the animal pharmacology and toxicology studies that have already been done, along with detailed information and protocol for future clinical studies, also includes the chemical structure of the compound and the company’s plan for manufacture

7 years

New Drug application) Can be filed after the IND phases are complete, can take up to 30 months for approval, one the FDA gives approval the drug becomes available for physicians to prescribe (

rHI aka Humulin Insulin

1986

Cystic Fibrosis

Genital warts

1. Isolate the desirable gene

2. GEne is inserted into a vector

3. Scientsts use the vector to transform the cells of another organism

4. The GMO is isolated from cells that did not take up the vectoe

1998

Gives a company the sole and exclusive rights to manufacture and sell a drug (

Having the capacity to induce and allergy

An organism that does not itself cause disease but spreads it by distributing pathogens from one host to another.

is to educate the pt on the medication they are taking

Abatacept

Ustekinumab

Infliximab

Anemia from cancer, therapt, chronic renal failure

Rheumatoid artheitis and psoriasis

Psoriasis

Humira

Herceptin

Amevive