Genetics

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1
What is meiosis used for?
It is used for sexual reproduction to create gametes
2
Explain the process of meiosis
-the cell duplicates DNA
-the chromosome pairs line up in the centre of the cell
-the pairs are pulled apart, so each new cell only has one copy of each chromosome. one mothers, one fathers
-then the chromosomes line up again in the centre of the cell and divide again
- 4 gametes each with a single set of chromosomes
3
What is a haploid?
a cell with one set of chromosomes
4
What is a diploid?
a cell that contains both sets of chromosomes
5
Is meiosis haploid or diploid?
diploid cells turn to haploid to then make a diploid fertilised egg
6
What is DNA?
genetic material
7
What's the structure of DNA?
two strands foiled to form a double helix

Sugar phosphate backbone with base bonding. Each base attaches to the sugar

A, T, C, G bases
8
What base does base A attach to?
base T
9
What base does base C attach to?
base G
10
What base does the base T attach to?
base A
11
What base does base G attach to?
base C
12
Define genome
The whole of the genetic information of an organism
13
Define gene
segment of DNA that codes for a specific protein
14
How can DNA be extracted from fruit?
1. Mash up a kiwi and add salt and washing up liquid
2. Heat at 60 degrees for 5 minutes
3. Filter this
4. Cool the liquid and add ethanol
15
Define allele
Different forms of a gene
16
Why are there different inherited characteristics?
People have different alleles, dominant or recessive
17
Define chromosome
carriers of genetic information that are copied and passed to new cells
18
Define dominant allele
an allele that has the same effect on the phenotype whether it is present in the homozygous or heterozygous state
19
Define recessive allele
an allele that only has an effect on the phenotype when present in the homozygous state
20
Define homozygous
having two identical alleles of a gene
21
Define hetrozygous
having two different alleles of a gene
22
Define genotype
genetic makeup of an organism
23
Define phenotype
physical characteristics of an organism
24
Define gamete
a haploid male or female cell that unites with another of the opposite sex in sexual reproduction to form a zygote.
25
Define zygote
a diploid cell resulting from the fusion of two haploid gametes; a fertilized egg
26
What is monohybrid inheritance?
The inheritance of a single gene
27
What is a punnett square?
A chart that shows all the possible combinations of alleles
28
How is sex determined?
The egg always has an X chromosome.If the sperm has an X chromosome it will be a girl if it has a Y chromes, it will be a boy
29
How are phenotypes determined?
by which alleles are present in the gene (multiple genes rather then just a single gene)
30
What's influences the phenotype?
Genetic variation and environmental variation
31
What's genetic variation?
Differences in characteristics as a result of mutation and sexual reproduction
32
What's environmental variation?
different characteristics caused by the environment e.g nutrition
33
What was the human genome project?
When hundreds of scientists came together to find out the sequence of base pairs in a man and a women
34
What did the Human Genome Project allowed us to do?
to search for teens linked in inherited diseases and therefore their treatment, trace human migration patterns from the past
35
What is genetic variation?
differences that occur in individuals within a species usually from mutations
36
What are mutations?
changes in the genetic material
37
Do mutations always affect the phenotype?
most have no effect on phenotype
some will have a small effect
rarely, others determine phenotype
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