1how many types of immune response are there
innate and adaptive
2immune system play a major role against
Non self antigen
self altered antigen
3Non self antigen are also called as
Exogenous antigen
4Self altered antigens also called as
Endogenous antigens
5what are exogenous antigen
foreign molecules
6example of non self antigen
bacteria, fungi
7Immune system are used for
differentiate self and non self cell
8what is self altered antigen
which is infected by antigen
9example of self altered antigens
virus infected cell
bacterial infected cell
10types of immune system
2 types
innate and adaptive/acquired immunity
11b cells also known called as
B lymphocytes
12B cells synthesis and maturation in
Bone marrow
13B cells also express in
MHC class 2 molecules
14B cell receptor which antibody is present
Igm/ IgD
15Naive b cells are
Newly matured cells
16b cells differentiate into
plasma cells and memory cells
17plasma cell work are
antibody secretion
18primary response are how many days
7 days
19secondary response how many days
3 days
20how many types of t lymphocytes
3 types
t helper cell
t cytoxic cells
t regulatory cells
21t helper cell also know as
CD4+
22what are the antigen presenting cells are in t helper cell
b lymphocytes
dendritic cells
macrophages
23these antigen presenting cells express in
MHC class 2 molecules
24t cytotoxic cells also know as
CD8+
25t cytotoxic cells functions are
killing of cells infected with intracellular pathogens
26t cytotoxic cells are involved in
performing- granenzyme mediated cytotoxic killing
27t cytotoxic results in
apoptosis
28t regulatory cells also know as
suppressor cell
29t regulatory cell function
supposing of immune response
regulation of immune response
30what are the receptors are present in t regulatory cells
t cell receptors
Cd3+ co receptor
31antigen presenting cells are
t helper cell
32types of organs of immune system
2 types
primary lymphoid organs
secondary lymphoid organ
33what are primary lymphoid organ
bone marrow
thymus
burse of fabricious(birds)
34what are secondary lymphoid organ
spleen
lymph node
MALT, GALT
35functions of primary lymphoid organ
synthesis and maturation of immune cells
provide growth factor for maturation
36functions of secondary lymphoid organ
antibody production
effector response
antigen trapping
37The cell from the bone marrow are
hematopoitic stem cell
38hematopoietic stem cell also called as
multipotent stem cell
39what is hematopoiesis
synthesis of blood cells
40harmatopoietic stem cells are divided into
2 types
lymphoid progenitor
myeloid progenitor
41The lymphoid progenitor is divided into
2 types
pro b cell
pro t cell
42pro t cell matured in
thymus
43b cells synthesis and maturation is involved in which selection
negative selection
44immature b cells is divided into
recognise self antigen
no recognition of self antigen
45if it is recognise self antigen what will happen
apoptosis is occured
46if it is no recognition of self antigen what will happen
it transport to secondary lymphoid organ
47
maturation of t cells is occur in
thymus
48as age increases what happen to thymus
decline in thymic function
49t cells play a major role in
cell mediated immunity
50in cell mediated immunity what are the types of t cells are involved
t helper cell
t cytotoxic cell
51what is thymactoised mice mean
thymus removed from new born
52what is digcorg syndrome
thymic aphasia
thymus fail to develop
absence of cell mediated immunity
53what is nude mice
absence of hair and it is used for experiment
54in nude mice which gene is mutant
foxn1 gene is mutant
55in t cell maturation what are the selection are involved
positive selection
negative selection
56in thymus double negative is convert into
double positive
57in thymus double positive is convert into
single positive
58in thymus single positive is convert into
t helper cell and t cytotoxic cell
59in thymus what is the ratio of t helper cell and t cytotoxic cell
2:1
60obtained ratio is occurred in which site
luman site
61why b cells have only negative selection
because it directly interact with antigen