ADHD Drug Dosing

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1
Dexmethylphenidate (Focalin) doses/day
2-3
2
Dexmethylphenidate (Focalin) initial dose
5mg
3
Dexmethylphenidate (Focalin) max dose
20mg
4
Dexmethylphenidate (Focalin) special comments
High fat meal may delay peak by 1.5 hours
5
Methylphenidate (Ritalin, Methylin) doses/day
2-3
6
Methylphenidate (Ritalin, Methylin) initial dose
10mg
7
Methylphenidate (Ritalin, Methylin) max dose
60mg
8
Methylphenidate (Ritalin, Methylin) special comments
Take 30-45 min before meals when possible
9
Methytlphenidate (Concerta) doses/day
1
10
Methytlphenidate (Concerta) initial dose
P: 18mg
A: 18-36mg
11
Methytlphenidate (Concerta) max dose
6-12 years: 54mg
>13 years: 72mg
Do not exceed 2mg/kg/day
12
Methytlphenidate (Concerta) special comments
Nonabsorbable tablet is 22% IR and 78% CR
13
MPH-IR Dose 5mg 2-3 times/day
MPH-OROS (Concerta) Dose 18mg daily
14
MPH-OROS (Concerta) Dose 18mg daily
MPH-IR Dose 5mg 2-3 times/day
15
MPH-IR Dose 10mg 2-3 times/day
MPH-OROS (Concerta) Dose 36mg daily
16
MPH-OROS (Concerta) Dose 36mg daily
MPH-IR Dose 10mg 2-3 times/day
17
MPH-IR Dose 15mg 2-3 times/day
MPH-OROS (Concerta) Dose 54mg daily
18
MPH-OROS (Concerta) Dose 54mg daily
MPH-IR Dose 15mg 2-3 times/day
19
MPH-IR Dose 20mg 2-3 times/day
MPH-OROS (Concerta) Dose 72mg daily
20
Methylphenidate (Jornay PM) doses/day
1
21
Methylphenidate (Jornay PM) initial dose
20mg
22
Methylphenidate (Jornay PM) max dose
100mg
23
Methylphenidate (Jornay PM) special notes
Taken in evening between 6:30-9:30 PM
Dose is not equivalent to oral MPH dose
24
Methylphenidate transdermal (Daytrana) doses/day
1
25
Methylphenidate transdermal (Daytrana) initial dose
10mg
26
Methylphenidate transdermal (Daytrana) max dose
30mg
27
Methylphenidate transdermal (Daytrana) special notes
Apply to hip. Remove after 9 hours. Absorption may continue for several hours after removal
Dose is not equivalent to oral MPH doses
28
Mixed amphetamine salts (Adderall) doses/day
2-3
29
Mixed amphetamine salts (Adderall) intial dose
5-10mg
30
Mixed amphetamine salts (Adderall) max dose
40mg
31
Mixed amphetamine salts (Adderall) special notes
Contains d-amphetamine and l-amphetamine salts in 3:1 ratio
32
Mixed amphetamine salts (Adderall XR) doses/day
1
33
Mixed amphetamine salts (Adderall XR) initial dose
P: 10mg
A: 20mg
34
Mixed amphetamine salts (Adderall XR) max dose
P: 30mg
A: 60mg
35
Mixed amphetamine salts (Adderall XR) special notes
Contains d-amphetamine and l-amphetamine salts in 3:1 ratio.
Cap is 50% IR and 50% DR beads. Mimics BID dosing
36
Lisdexamfetamine (Vyvanse) doses/day
1
37
Lisdexamfetamine (Vyvanse) initial dose
30mg
38
Lisdexamfetamine (Vyvanse) max dose
70mg
39
Lisdexamfetamine (Vyvanse) special notes
Continuous-release cap. High fat meal may delay peak by 1 hour
40
Atomoxetine (Strattera) doses/day
1-2
41
Atomoxetine (Strattera) initial dose
< or equal to 70 kg: 0.5mg/kg/day
> 70 kg: 40mg
42
Atomoxetine (Strattera) max dose
< or equal to 70 kg: 1.4 mg/kg/day
> 70 kg: 100mg
Do not exceed 100mg daily
43
Atomoxetine (Strattera) special comments
Moderate hepatic impairment: Decrease initial/target dose by 50%
Severe hepatic impairment: Decrease initial/target dose by 75%
High fat meals may delay peak by 3 hours
Dose adjustments with concomitant CYP2D6 inhibitors
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