ADHD Drug Dosing

2-3

5mg

20mg

High fat meal may delay peak by 1.5 hours

2-3

10mg

60mg

Take 30-45 min before meals when possible

1

P: 18mg
A: 18-36mg

6-12 years: 54mg
>13 years: 72mg
Do not exceed 2mg/kg/day

Nonabsorbable tablet is 22% IR and 78% CR

MPH-OROS (Concerta) Dose 18mg daily

MPH-IR Dose 5mg 2-3 times/day

MPH-OROS (Concerta) Dose 36mg daily

MPH-IR Dose 10mg 2-3 times/day

MPH-OROS (Concerta) Dose 54mg daily

MPH-IR Dose 15mg 2-3 times/day

MPH-OROS (Concerta) Dose 72mg daily

1

20mg

100mg

Taken in evening between 6:30-9:30 PM
Dose is not equivalent to oral MPH dose

1

10mg

30mg

Apply to hip. Remove after 9 hours. Absorption may continue for several hours after removal
Dose is not equivalent to oral MPH doses

2-3

5-10mg

40mg

Contains d-amphetamine and l-amphetamine salts in 3:1 ratio

1

P: 10mg
A: 20mg

P: 30mg
A: 60mg

Contains d-amphetamine and l-amphetamine salts in 3:1 ratio.
Cap is 50% IR and 50% DR beads. Mimics BID dosing

1

30mg

70mg

Continuous-release cap. High fat meal may delay peak by 1 hour

1-2

< or equal to 70 kg: 0.5mg/kg/day
> 70 kg: 40mg

< or equal to 70 kg: 1.4 mg/kg/day
> 70 kg: 100mg
Do not exceed 100mg daily

Moderate hepatic impairment: Decrease initial/target dose by 50%
Severe hepatic impairment: Decrease initial/target dose by 75%
High fat meals may delay peak by 3 hours
Dose adjustments with concomitant CYP2D6 inhibitors