1pregabalin initial dose
50mg TID
2pregabalin renal dose
XR: reduce dose by 50%
IR: max 75-300mg daily
3pregabalin extreme renal dose
XR: not recommended
IR: max 25-100mg daily
4paroxetine (Paxil) initial dose
IR: 20mg
CR: 25mg
5paroxetine (Paxil) renal dose
IR: max 40mg
CR: max 50mg
6paroxetine (Paxil) hepatic dose
IR: max 40mg
CR: max 50mg
7paroxetine (Paxil) geriatric dose
N/A
8escitalopram (Lexapro) intitial dose
10mg
9escitalopram (Lexapro) renal dose
use with caution
10escitalopram (Lexapro) hepatic dose
max 10mg
11escitalopram (Lexapro) geriatric dose
max 10mg
12citalopram (Celexa) initial dose
20mg
13citalopram (Celexa) renal dose
use with caution
14citalopram (Celexa) hepatic dose
max 20mg
15citalopram (Celexa) geriatric dose
max 20mg
16sertraline (Zoloft) initial dose
25mg
17sertraline (Zoloft) renal dose
N/A
18sertraline (Zoloft) hepatic dose
lower or less frequent dose
19sertraline (Zoloft) geriatric dose
lower or less frequent dose
20fluoxetine (Prozac) initial dose
20mg
21fluoxetine (Prozac) renal dose
N/A
22fluoxetine (Prozac) hepatic dose
lower or less frequent dose
23fluoxetine (Prozac) geriatric dose
lower or less frequent dose
24venlafaxine XR (Effexor) starting dose
IR and ER: 37.5mg
25venlafaxine XR (Effexor) renal dose
decrease by 25%-50%
26venlafaxine XR (Effexor) hepatic dose
decrease by over 50%
27venlafaxine XR (Effexor) geriatric dose
N/A
28duloxetine (Cymbalta) initial dose
30-60mg
29duloxetine (Cymbalta) renal dose
avoid use
30duloxetine (Cymbalta) hepatic dose
avoid use
31duloxetine (Cymbalta) geriatric dose
N/A
32diazepam relative equivalent potency
5
33diazepam onset of action
rapid
34alprazolam relative equivalent potency
0.5
35alprazolam onset of action
rapid-intermediate
36clonazepam relative equivalent potency
0.25
37clonazepam onset of action
intermediate
38lorazepam relative equivalent potency
1
39lorazepam onset of action
intermediate
40Oxazepam relative equivalent potency
15
41Oxazepam onset of action
intermediate-slow
42Benzodiazepams that are safer in hepatically impaired patients
"LOT" lorazepam, oxazepam, temazepam
43buspirone (Buspar) initial dose
7.5mg BID
44buspirone (Buspar) hepatic dose
not recommended
45buspirone (Buspar) renal dose
not recommended
46buspirone (Buspar) elderly dose
max 20-30mg daily
47hydroxyzine (Atarax, Vistaril) intitial dose
25mg BID (can be scheduled or used as needed)
48SSRIs used for GAD
paroxetine
escitalopram
citalopram
sertraline
49SNRIs used for GAD
venlafaxine XR
duloxetine
50SSRIs used for PTSD
paroxetine
sertraline
fluoxetine
51Mirtazapine max dose PTSD
60mg once daily
52SSRIs used for OCD
fluoxetine
fluvoxamine
paroxetine
sertraline
53Clomipramine initial dose
25mg once daily