Anxiety-Related Disorders Drugs
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1
pregabalin initial dose
50mg TID
2
pregabalin renal dose
XR: reduce dose by 50%
IR: max 75-300mg daily
IR: max 75-300mg daily
3
pregabalin extreme renal dose
XR: not recommended
IR: max 25-100mg daily
IR: max 25-100mg daily
4
paroxetine (Paxil) initial dose
IR: 20mg
CR: 25mg
CR: 25mg
5
paroxetine (Paxil) renal dose
IR: max 40mg
CR: max 50mg
CR: max 50mg
6
paroxetine (Paxil) hepatic dose
IR: max 40mg
CR: max 50mg
CR: max 50mg
7
paroxetine (Paxil) geriatric dose
N/A
8
escitalopram (Lexapro) intitial dose
10mg
9
escitalopram (Lexapro) renal dose
use with caution
10
escitalopram (Lexapro) hepatic dose
max 10mg
11
escitalopram (Lexapro) geriatric dose
max 10mg
12
citalopram (Celexa) initial dose
20mg
13
citalopram (Celexa) renal dose
use with caution
14
citalopram (Celexa) hepatic dose
max 20mg
15
citalopram (Celexa) geriatric dose
max 20mg
16
sertraline (Zoloft) initial dose
25mg
17
sertraline (Zoloft) renal dose
N/A
18
sertraline (Zoloft) hepatic dose
lower or less frequent dose
19
sertraline (Zoloft) geriatric dose
lower or less frequent dose
20
fluoxetine (Prozac) initial dose
20mg
21
fluoxetine (Prozac) renal dose
N/A
22
fluoxetine (Prozac) hepatic dose
lower or less frequent dose
23
fluoxetine (Prozac) geriatric dose
lower or less frequent dose
24
venlafaxine XR (Effexor) starting dose
IR and ER: 37.5mg
25
venlafaxine XR (Effexor) renal dose
decrease by 25%-50%
26
venlafaxine XR (Effexor) hepatic dose
decrease by over 50%
27
venlafaxine XR (Effexor) geriatric dose
N/A
28
duloxetine (Cymbalta) initial dose
30-60mg
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duloxetine (Cymbalta) renal dose
avoid use
30
duloxetine (Cymbalta) hepatic dose
avoid use
31
duloxetine (Cymbalta) geriatric dose
N/A
32
diazepam relative equivalent potency
5
33
diazepam onset of action
rapid
34
alprazolam relative equivalent potency
0.5
35
alprazolam onset of action
rapid-intermediate
36
clonazepam relative equivalent potency
0.25
37
clonazepam onset of action
intermediate
38
lorazepam relative equivalent potency
1
39
lorazepam onset of action
intermediate
40
Oxazepam relative equivalent potency
15
41
Oxazepam onset of action
intermediate-slow
42
Benzodiazepams that are safer in hepatically impaired patients
"LOT" lorazepam, oxazepam, temazepam
43
buspirone (Buspar) initial dose
7.5mg BID
44
buspirone (Buspar) hepatic dose
not recommended
45
buspirone (Buspar) renal dose
not recommended
46
buspirone (Buspar) elderly dose
max 20-30mg daily
47
hydroxyzine (Atarax, Vistaril) intitial dose
25mg BID (can be scheduled or used as needed)
48
SSRIs used for GAD
paroxetine
escitalopram
citalopram
sertraline
escitalopram
citalopram
sertraline
49
SNRIs used for GAD
venlafaxine XR
duloxetine
duloxetine
50
SSRIs used for PTSD
paroxetine
sertraline
fluoxetine
sertraline
fluoxetine
51
Mirtazapine max dose PTSD
60mg once daily
52
SSRIs used for OCD
fluoxetine
fluvoxamine
paroxetine
sertraline
fluvoxamine
paroxetine
sertraline
53
Clomipramine initial dose
25mg once daily
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