1Hypertension
Complications are directly correlated with ______________.
Blood pressure
- The risk of CV disease doubles with every 20/10mmHg increase
2Hypertension
Which blood pressure is a stronger predictor of complications in those over 50?
SBP >>>>>> DBP
3Hypertension
What are the classifications of HTN?
Based on two different readings from 2 seperate visits
4Hypertension
Goal BP for most patients including ASCVD, DM and CKD?
< 130/80
5Hypertension
What patients is the goal of SBP < 130 (no regard to DBP)?
Older ambulatory, community dwelling patients
6Hypertension
What patients is the goal of SBP <140 or <150 (no regard to DBP)?
- Institutionalized older patients
- High disease burden
- Limited life-expectancy
7Hypertension Tx
Preferred first-line agents for most patients? (4)
- ACEi
- ARBs
- CCBs
- Thiazides
8Hypertension Tx
T/F: Using low-dose combinations provides greater BP control compared to higher doses of single agents.
TRUE!
9Hypertension Tx
Benefits of low-dose combinations?
- Better BP control
- Fewer drug related AEs
- Better adherence is they come in one pill
10Hypertension Tx
What is critical to improve outcomes in geriatric patients?
Patient-centered considerations
- Not treating every person to the < 130/80 goal
11Stroke PPx in A. Fib
What is the main thing we are trying to balance?
Risk of clot vs. Risk of bleed
12Stroke PPx in A. Fib
What score is used to determine stroke risk in A. fib?
What is the interpretation?
CHA2DS2-VASc
- 2+ needs anticoagulation
- Anyone over 75 automatically needs anticoagulation
13Stroke PPx in A. Fib
What score is used to determine the risk of bleeding on anticoagulation?
HAS-BLED
14Stroke PPx in A. Fib
T/F: Anticoagulants are often times over prescribed in patients over 75.
FALSE -- Under Prescribed
15Stroke PPx in A. Fib
What is frequently listed as a barrier to anticoagulation? Is it actually as big as a barrier as it seems?
Falling
- A patient would have to fall 295 times in one year for
the risk of anticoagulation to outweigh its benefits
16Stroke PPx in A. Fib
What are the considerations to using warfarin in the elderly?
- Drug and disease interactions
- Monitoring
17Stroke PPx in A. Fib
What are the considerations to using DOACs in the elderly?
- Limited indications (cannot be used in valves)
- Dose adjustments (renal)
- QD and BID dosing
18Stroke PPx in A. Fib
Which DOACs are on the Beers list?
Dabigatran and Rivaroxaban
19Hyperlipidemia
What is first-line to lower LDL?
Statins
20Hyperlipidemia
What are the statin intensities?
21Hyperlipidemia
Moderate-intensity statin use is supported in patients > 75 who have what 3 diseases?
- Clinical ASCVD
- DM
- Tolerated statins and wish to continue
22Hyperlipidemia
What is the difference between using statins in patients > 75 for primary vs. secondary prevention?
- Primary: Unclear on the age cut off for benefit
- Secondary: Continued to see benefit in patients > 75
23Hyperlipidemia
Decision to initiate statin therapy in patients > 75 for primary prevention should consider what 3 things?
- Comorbidities
- Safety
- Priorities of care
24Hyperlipidemia
What are the concerns with using statins in the elderly? (5)
- Myopathy
- Hepatic injury
- Cognitive dysfunction
- Diabetes
- DDIs
25Diabetes
ADA recommends screening all adults over age ___ every ___ years.
Over 45
Every 3 years
26Diabetes
What are the presentations of glocuria, increased osmolality, and insulin deficiency in older adults?
- Glucosuria: Incontinence
- Inc. osmolality: Dehydration, confusion, delirium
- Insulin def: Anorexia, weight loss
27Diabetes
What is the relationship between glucose control and cognitive decline?
Diabetics have higher incidences of all-cause:
- Dementia
- Alzheimer disease
- Vascular dementia
Poor glycemic control is associated with a decline in cognitive function
Cognitive dysfunction can impact all areas of diabetes care:
- Glucose monitoring
- Insulin adjustments
- Timing/content of diet
28Diabetes
Goal of treatment?
- ADA A1c goal for most adults is < 7%
- Individualized A1c goals are key in older adults
- AVOID hypoglycemia
29Diabetes
A1c goals for patients over 75 based on health
30Diabetes Tx
Treatment options and considerations for elderly patients
31Diabetes Tx
What is the main complication of treatment in elderly patients?
S/S of this complication?
Hypoglycemia
- Hunger
- Sweating
- Mental status
- Changes
- Poor coordination
- Seizures
- Stroke
32Depression
Increase incidence of what type of depression with age?
Subsyndromal depression
33Depression
What are the treatment options?
- Psychotherapy
- SSRI (1st line): Hyponatremia, EPS, bleeding
- SNRI:↑ BP, GI upset, sexual dysfunction, sleep changes, hyponatremia
- Bupropion
- Mirtazapine
- TCAs
34What are the considerations of inhaler use in older adults?
- Decreased physical strength
- Poor manual dexterity
- Lung function considerations
- Impaired cognitive function
- Inhaler education/instruction challenges: Written handout, patient/provider demonstration, video, checklist
- Fixed income and Part D coverage gap
35What vaccines should older adults get?
- Influenza
- Pneumococcal
- Herpes zoster
- Tetanus-diphtheria