Neurology

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1
excitatory neurotransmitter produced at the raphe nuclei of the brainstem, decreased during NREM sleep, and almost absent during REM
sleep
  • serotonin
  • dopamine
  • melatonin
  • glutamate
2
This aphasia type of disturbances which involve understanding of oral or graphic symbols
  • Wernicke’s Aphasia (Receptive)
  • Global Aphasia
  • Broca’s Aphasia (Expressive)
3
Disturbances which involve understanding of oral or graphic symbols
  • Receptive Aphasia (Wernicke’s)
  • Expressive Aphasia (Broca’s)
  • Global Aphasia
4
Almost total language loss, manifested in minimal response in every phase of communication
  • Global Aphasia
  • Broca’s Aphasia (Expressive)
  • Wernicke’s Aphasia (Receptive)
5
A patient with a right medial medullary stroke (Dejerine syndrome) will have which of the following findings?
  • Tongue deviates to the right, ipsilateral hemiparesis
  • Tongue deviates to the left, ipsilateral hemiparesis
  • Tongue deviates to the right, contralateral hemiparesis
  • Tongue deviates to the left, contralateral hemiparesis
6
A patient has a left vagus nerve (CN X) lesion. What will be observed when they say "ah"?
  • Bilateral palatal weakness
  • Uvula deviates to the right
  • No movement of the uvula
  • Uvula deviates to the left
7
A 55-year-old presents with right-sided ptosis, mydriasis, and eye positioned "down and out," along with left-sided weakness. Where is the lesion?
  • Right medulla (Lateral medullary syndrome)
  • Left pons (Millard-Gubler syndrome)
  • Left midbrain (Weber syndrome)
  • Right midbrain (Weber syndrome)
8
Which structure is affected in Locked-In Syndrome, causing quadriplegia but preserving eye movement?
  • Pons
  • Midbrain
  • Medulla
  • Cerebellum
9
A 65-year-old male presents with right-sided tongue deviation when protruding his tongue and left-sided uvula deviation when saying "ah." Which of the following best localizes the lesion?
  • Right Vagus Nerve (CN X)
  • Left Vagus Nerve (CN X)
  • Left Hypoglossal Nerve (CN XII)
  • Right Hypoglossal Nerve (CN XII)
10
Which of the following findings is most characteristic of medial medullary syndrome (Dejerine Syndrome)?
  • Ipsilateral facial weakness, contralateral hemiparesis, and ataxia
  • Ipsilateral tongue deviation, contralateral hemiparesis, and contralateral proprioceptive loss
  • Bilateral limb weakness with preserved facial movements
  • Ipsilateral Horner’s syndrome, contralateral pain and temperature loss, and hoarseness
11
A lesion in the right hypoglossal nerve (CN XII) will cause the tongue to:
  • Deviate to the left
  • Move normally but have reduced strength bilaterally
  • Deviate to the right
  • Have no deviation, but show fasciculations
12
This tumor is contains of well differentiated tissues such as dermis, muscles and bones
  • Germinoma
  • Epidermoid
  • Teratoma
13
This is a cyctic tumor arising from the unembryonological remnant in the anterior root of the third ventricle
  • Dermoid Cyst
  • Coloid Cyst
  • Pituatary Adenoma
14
This implies rapid growth for differentiation increased cellularity, mitosis, necrosis and vascular proliferation, but metastasis to extracranial sites rarely occur
  • Malignant Intracranial Tumor
  • Benign Intracranial Tumor
15
This occurs in the within the perinchymal cerebellar or spinal cord
  • Meningioma
  • Haemangioblastoma
  • Ganglioglioma
16
In this tumor medulla blastoma arise in the cerebellar vermis small closely pack cells are often arranged in rose set surrounding abortive axons.
  • Ganglioglioma
  • Peniocytoma
  • Primitive Neuroectodermal Tumors
17
PNET or small shell are malignant tumor of childhood, commonly occuring in what location
  • Supratentorially
  • Infratentorially
18
Other name for shwannoma
  • Neurocytoma
  • Neurinoma
19
This involves the spinal nerve root or peripheral nerve and it is rarely affects cranial nerves and has greater tendedcy undergo malignant change than shwannoma.
  • Neurocytoma
  • Neurofribroma
  • Neurinoma
20
This intecranial tumors permit separation into four grade depending on the degree of malignancy
  • Ependymoma
  • Oligodendroglioma
  • Astrocytoma
21
what is the visual field deficits when the lesion is in the optic nerve
  • Monocular Vision Loss (blindness)
  • Central Scotoma
  • Macular Degeneration
22
When the lesion is in the optic radiation
  • Contralateral Homonymous Hemianopsia/Hemianopia
  • Contralateral Inferior Quadrantinopia
  • Contralateral Superior Quadrantinopia
23
What visual deficit when the lesion is on the optic tract
  • Bitemporal Hemianopsia
  • Macular Degeneration
  • Contralateral Hemianopsia
24
Lesion is in the Optic radiation and originated in the lateral geniculate nucleus
  • Contralateral Inferior Quadrantinopia
  • Contralateral Superior Quadrantinopia
  • Contralateral Homonymous Hemianopia with Macular Sparring
25
It is an excitatatory neurotransmitter produced in the substantia nigra, ventral tegmental area and hypothalamus of the brain
  • dopamine
  • glutamate
  • norepinephrine
26
This inhibitory neurotransmitter is produced in the pineal gland, is located below the corpus callusom and part of the endocrine system.
  • melanin
  • melatonin
  • GABA
27
The neurons that produce these neurotransmitters are located in the perifornical area of the dorsolateral hypothalamus and project to all the areas of the CNS and
spinal cord. Activation of these neurons during wakefulness is produced by
intrinsic depolarization and by glutamatergic activation
  • GABA
  • Hypocretin(Orexin)
  • Nitric Oxide
  • Glutamate
28
is an excitatory neurotransmitter important in cognitive function.
Levels of this neurotransmitter in the hypothalamus and cortex are elevated during wakefulness and during REM sleep.
  • Glutamate
  • Aspertate
  • Acetylcholine
29
These are the neurotransmitters that binds to both muscarinic and nicotinic receptors.
  • Dopamine
  • Serotonin
  • Acetylcholine
30
An Optic chiasm lesion, usually related to pituitary tumor,will result in____________with loss of the temporal or lateral visual field from each eye
  • Contralateral homonymus hemianopsia
  • Bitemporal Hemianopsia
31
is a visual field defect that affects the opposite side of the eye from the side of a brain lesion.
  • contralateral homonymous hemianopsia
  • bitemporal hemianopsia
32
CN III damage that results to inability to raise the eyelid on the affected side
  • Mydriasis
  • Anisocoria
  • Ptosis
33
A CN III palsy would result in a dilated pupil or __________ on the affected side
  • Mydriasis
  • Ptosis
  • Anisocoria
34
A CN III palsy would results in an unequal pupil size or ___________ with the affected pupil wider than the non affected side
  • Mydriasis
  • Ptosis
  • Anisocoria
35
Is a pathological condition related to CN V function and characterized by brief but repeated sharp pain in the distributions of the Trigeminal nerve often accompanied by motor tics of facial muscles ( through CN VII) which occur reflexively
  • Stroke
  • Bell's Palsy
  • Tic Duoluoreux
36
A lesion to CN ____ will result in anaesthesia and loss of general senses of the face and anterior head on the affected side, including the Ipsilateral corneal sensation. Therefore both Ipsilateral and consensual corneal reflex will be lost
  • CN III
  • CN IV
  • CN V
37
paralysis of upper and lower face on the affected side occurs.
  • Bell's palsy
  • stroke
  • tic duoluoreux
38
Failure of sound conduction to the cochlea
  • Semineural Deafness
  • (Pure Word) or Cortical Deafness
  • Conductive Deafness
39
due to failure of action potential procedure or transmission due to disease of the cochlea, cochlear nerve, or cochlear central connections.
  • Conductive deafness
  • Sensorineural deafness
  • Cortical deafness
40
a bilateral or dominant posterior temporal lobe( auditory cortex) lesion produces a failure to understand spoken language despite preserved hearing
  • Cortical deafness
  • Sensorineural deafness
  • Conductive deafness
41
Sensation of ringing,buzzing ,pulsing, hissing, or singing quality.
  • Vertigo
  • Tinnitus
42
These cranial nerve forms the gag reflex
  • CN 9 and 10
  • CN 4, 5 and 7
  • CN 2 and 3
43
The person with an ____________ nerve lesion would exhibit the unique combination of weakness the neck to the opposite side and weakness/paralysis in elevating the scapula in the ipsilateral side.
  • Accessory
  • Glossopharyngeal
  • Trigeminal
44
Lesion to this cranial nerve results in paralysis of the tongue with significant difficulty with speech, chewing and swallowing
  • CN XI(Spinal Accessory)
  • CN XII(Hypoglossal)
  • CN X(Vagus)
45
You directed the pen light on the L eye and the L pupil constricted but the R eye did not constrict, what is the CN affectation and its laterality
  • R CN 3
  • L CN 2
  • R CN 2
  • L CN 3
46
most common primary tumor
  • Astrocytoma
  • Oligodendroglioma
  • Ependymoma
47
Astrocytoma Grade- less common low-grade astrocytomas including the psilocybin type
  • Grade III
  • Grade I
  • Grade IV
  • Grade II
48
Astrocytoma Grade- anaplastic astrocytomas
  • Grade II
  • Grade III
  • Grade IV
  • Grade I
49
Astrocytoma Grade- Diffuse types(fibrillation, protoplasmic and gemistocytic
  • Grade IV
  • Grade I
  • Grade II
  • Grade III
50
Astrocytoma Grade- the most malignant type- glioblastoma occurs most frequently and widely infiltrates surrounding tissues
  • Grade IV
  • Grade II
  • Grade I
  • Grade III
51
Occurs anywhere throughout the ventricular system and spinal canal, but is particularly common in the 4th ventricle and Caudia equina
  • Astrocytoma
  • Oligodendroglioma
  • Ependymoma
52
Rare tumor and uncommon cause of hydrocephalus
  • Ependymoma
  • Choroid Plexus Papilloma
  • Astrocytoma
53
Arises from arachnoid granulations
  • Meningioma
  • Ependymoma
  • Schwannoma
54
AKA neurolimmoma or neurinoma is a slow growing tumor of schwann cells
  • Schwannoma
  • Meningioma
  • Ependymoma
55
Tumor of schwann cells , fibrolasts and perineureal-like cells producing a fusiform expansion through which nerve fibers run.
  • Neurofibroma
  • Schwannoma
56
BA for Primary Somatosensory Cortex
  • 4
  • 5
  • 1 2 and 3
57
BA for primary visual cortex
  • 17
  • 6
  • 22
  • 44, 45
58
BA for primary auditory cortex
  • 22
  • 39, 40
  • 44,45
59
BA for Broca's area/ motor speech programming
  • 37
  • 39,40
  • 44, 45
60
is used to describe a complete absence of the sense of smell.
  • Aphasia
  • Anosmia
  • Agraphia
  • Apraxia
61
Abnormal visual acuity in which the person cannot see clearly at distances
  • Myopia (nearsightedness)
  • Hyperopia(farsightedness)
  • Cataracts
62
Abnormal visual acuity in which the person can see most clearly at distances but can not see things up close.
  • Myopia(nearsighted)
  • Hyperopia(farsighted)
  • Cataracts
63
Abnormal Visual Acuity in which the lens of the eyes becomes cloudy or opaque. Cataracts also allow less light
from the environment to reach the retina
  • Cataract
  • Myopia
  • Hyperopia
64
A patchy or sporadic distribution of visual field loss can occur from the patchy CNS demyelination of
multiple sclerosis.
  • Hemianopsia
  • Macular Degeneration
  • Contralateral Homonomous Hemianopsia
  • Scotoma
65
You directed the pen light on the L eye and it did not constrict however the R eye constricted , what is the nerve affectation and the laterality
  • R CN 2
  • L CN 3
  • R CN 3
  • L CN 2
66
describes an affected eye that is deviated laterally
  • Internal Strabismus
  • Pseudostrabismus
  • External Strabismus
  • Diplopia
67
describes an affected eye that is medially deviated
  • External Strabismus
  • Pseudostrabismus
  • Internal Strabismus
  • Diplopia
68
If the eyes appear to be differently aligned but the reflection of room lights are similarly placed on each cornea.
  • Internal strabismus
  • External strabismus
  • Diplopia
  • Pseudostrabismus
69
inward turning of the eye
  • Esotropia
  • Hypotropia
  • Hypertropia
  • Exotropia
70
Outward turning of the eye
  • Hypertropia
  • Esotropia
  • Exotropia
  • Hypotropia
71
Upward turning of the eye
  • Exotropia
  • Hypotropia
  • Esotropia
  • Hypertropia
72
Location of Weber Syndrome
  • Medial Basal Midbrain
  • Lateral pons
  • Bilat. basal pons
  • Tegmentum of the midbrain
  • Lateral medulla
73
Location of Benedict syndrome
  • Tegmentum of the midbrain
  • Lateral Pons
  • Medial Basal Midbrain
  • Lateral medulla
  • Bilat. basal pons
74
Locked in Syndrome Location
  • Medial Basal Midbrain
  • Lateral Medulla
  • Lateral pons
  • Bilat. Basal Pons
  • Tegmentum of the midbrain
75
Millard-Gubler Syndrome Location
  • Lateral Medulla
  • Tegmentum of the midbrain
  • Medial Basal Midbrain
  • Lateral Pons
  • Bilat. Basal Pons
76
Wallenburg Syndrome Location
  • Bilat. Basal Pons
  • Lateral Medulla
  • Tegmentum of the midbrain
  • Medial Basal Midbrain
  • Lateral Pons
77
What cranial nerve supplied the Lateral Rectus muscles of the Eye
  • CN 3
  • CN 6
  • CN 4
78
What Cranial nerve supplies the superior oblique muscles of the eye
  • Cranial Nerve 6
  • Cranial Nerve 4
  • Cranial Nerve 3
79
What Cranial Nerve supplies the Medial rectus, Inferior Oblique, Superior Rectus, and Inferior Rectus muscles of the eye
  • Cranial 6
  • Cranial 4
  • Cranial Nerve 3
80
an illusion of rotatory movement due to disturbed orientation of the body in space. The sufferer may sense that the environment is moving. Vertigo may result from disease of the labyrinth,
vestibular nerve or their central connections
  • Vitiligo
  • Vertigo
  • Tinnitus
81
Transient attacks of vertigo, associated with a change in head position
  • Meneire's Disease
  • Vestibular Neuritis
  • Benign Paroxysmal Positional Vertigo
82
You noticed the pt. has a difficulty elevating their L eye( look upward) , what muscle is affected?
  • Superior Oblique
  • Inferior Oblique
  • Inferior Rectus
  • Superior Rectus
83
You noticed the pt. L eye is elevated and adducted, what eye muscles are weak?
  • L Superior Rectus
  • L Superior Oblique
  • L inferior Rectus
  • L Inferior Oblique
84
You noticed the pt. eye is medially deviated, what eye muscle is weak?
  • Medial Rectus
  • Lateral Rectus
  • Inferior Oblique
  • Superior Oblique
85
You noticed the pt. eye is laterally deviated , what muscles are weak?
  • Medial Rectus
  • Lateral Rectus
  • Inferior Oblique
  • Superior Oblique
86
Benzodiazepines used to treat insomnia , except:
  • Temazepam
  • Estazolam
  • Flurazepam
  • Zolpidem
  • Triazolam
  • Quazepam
87
Melatonin receptor agonist:
  • Doxepin
  • Zaleplon
  • Ramelteon
88
Tricycle antidepressant
  • Doxepin
  • Souvorexant
  • Eszopicione
89
Orexin receptor agonist:
  • Zoldipem
  • Ramelteon
  • Doxepin
  • Lemborexant
90
promotes wakefulness via excitatory effects on the nuclei of the RAS and inhibitory effects on the sleep-active projection neurons of the
VLPO
  • Norepinephrine
  • Orexin
  • Serotonin
  • Histamine
91
It is predominantly located in the locus ceruleus of the brain stem.These neurons fire during wakefulness, diminish activity during NREM sleep, and are quiet during REM sleep.
  • Serotonin
  • Norepinephrine
  • Glutamate
  • Melatonin
92
Associated with difficulty in initiating and maintaining sleep, characterized by frequent awakening or problems returning to sleep after awakenings, as well as early-morning awakening
with inability to return to sleep.
  • Hypersomnolence
  • Insomnia
  • Narcolepsy
93
Excessive sleepiness with recurrent periods of sleep or lapses into sleep within the day lasting for more than 9 hours per day and has difficulty being fully awake after abrupt awakening.
  • Hypersomnolence
  • Insomnia
  • Narcolepsy
94
Recurrent periods of an irrepressible need to sleep,lapsing into sleep, or
napping occurring within the day.
  • Insomnia
  • Narcolepsy
  • Hypersomnolence
95
Pressure for sleep builds up in our body as our
time awake increases
  • Homeostatic Sleep Drive
  • Circadian Rhythm
96
refers to the internal clock in humans that regulates sleep–wake cycles.
  • Homeostatic Sleep Drive
  • Circadian rhythm
97
Unusual behaviors during sleep, such as sleepwalking,sleep talking, or night terrors
  • Insomnia
  • Parasomnias
  • Hypersomnolence
98
Presents with pauses in breathing during sleep, often accompanied by snoring
  • Parasomnias
  • Sleep apnea
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